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Seung Bum Park
Seung Bum Park
Verified email at nih.gov
Title
Cited by
Cited by
Year
Modeling PNPLA3‐Associated NAFLD Using Human‐Induced Pluripotent Stem Cells
SG Tilson, CM Morell, AS Lenaerts, SB Park, Z Hu, B Jenkins, A Koulman, ...
Hepatology 74 (6), 2998-3017, 2021
432021
Ethanol and reactive species increase basal sequence heterogeneity of hepatitis C virus and produce variants with reduced susceptibility to antivirals
S Seronello, J Montanez, K Presleigh, M Barlow, SB Park, J Choi
PLoS One 6 (11), e27436, 2011
432011
Hepatitis C virus frameshift/alternate reading frame protein suppresses interferon responses mediated by pattern recognition receptor retinoic-acid-inducible gene-I
SB Park, S Seronello, W Mayer, DM Ojcius
Plos one 11 (7), e0158419, 2016
262016
Chlorcyclizine inhibits viral fusion of hepatitis C virus entry by directly targeting HCV envelope glycoprotein 1
Z Hu, A Rolt, X Hu, CD Ma, DJ Le, SB Park, M Houghton, N Southall, ...
Cell chemical biology 27 (7), 780-792. e5, 2020
202020
TM6SF2 promotes lipidation and secretion of hepatitis C virus in infected hepatocytes
A Boyer, SB Park, YS de Boer, Q Li, TJ Liang
Gastroenterology 155 (6), 1923-1935. e8, 2018
152018
SARS-CoV-2 omicron variants harbor spike protein mutations responsible for their attenuated fusogenic phenotype
SB Park, M Khan, SC Chiliveri, X Hu, P Irvin, M Leek, A Grieshaber, Z Hu, ...
Communications biology 6 (1), 556, 2023
132023
Genetically edited hepatic cells expressing the NTCP-S267F variant are resistant to hepatitis B virus infection
T Uchida, SB Park, T Inuzuka, M Zhang, JN Allen, K Chayama, TJ Liang
Molecular Therapy-Methods & Clinical Development 23, 597-605, 2021
122021
A dual conditional CRISPR-Cas9 system to activate gene editing and reduce off-target effects in human stem cells
SB Park, T Uchida, S Tilson, Z Hu, CD Ma, M Leek, M Eichner, SG Hong, ...
Molecular Therapy-Nucleic Acids 28, 656-669, 2022
112022
Targeting the fusion process of SARS-CoV-2 infection by small molecule inhibitors
SB Park, P Irvin, Z Hu, M Khan, X Hu, Q Zeng, C Chen, M Xu, M Leek, ...
MBio 13 (1), e03238-21, 2022
112022
Fluoxazolevir inhibits hepatitis C virus infection in humanized chimeric mice by blocking viral membrane fusion
CD Ma, M Imamura, DC Talley, A Rolt, X Xu, AQ Wang, D Le, T Uchida, ...
Nature microbiology 5 (12), 1532-1541, 2020
102020
Discovery and characterization of a novel HCV inhibitor targeting the late stage of HCV life cycle
SB Park, A Boyer, Z Hu, D Le, TJ Liang
Antiviral Therapy 24 (5), 371-381, 2019
52019
Discovery and optimization of a 4-aminopiperidine scaffold for inhibition of hepatitis C virus assembly
A Rolt, DC Talley, SB Park, Z Hu, A Dulcey, C Ma, P Irvin, M Leek, ...
Journal of medicinal chemistry 64 (13), 9431-9443, 2021
42021
ETHANOL, OXIDATIVE STRESS, AND HCV: DIRECT EFFECTS ON VIRAL REPLICATION AND MUTATION
J Choi, S Seronello, J Montanez, K Presleigh, T Vo, SB Park, M Barlow
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 36, 339A-339A, 2012
2012
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Articles 1–13