Follow
Alexander M Sevy
Alexander M Sevy
Verified email at vanderbilt.edu
Title
Cited by
Cited by
Year
Macromolecular modeling and design in Rosetta: recent methods and frameworks
JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ...
Nature methods 17 (7), 665-680, 2020
6462020
High frequency of shared clonotypes in human B cell receptor repertoires
C Soto, RG Bombardi, A Branchizio, N Kose, P Matta, AM Sevy, ...
Nature 566 (7744), 398-402, 2019
2942019
Protocols for molecular modeling with Rosetta3 and RosettaScripts
BJ Bender, A Cisneros III, AM Duran, JA Finn, D Fu, AD Lokits, BK Mueller, ...
Biochemistry 55 (34), 4748-4763, 2016
2032016
Multifunctional pan-ebolavirus antibody recognizes a site of broad vulnerability on the ebolavirus glycoprotein
P Gilchuk, N Kuzmina, PA Ilinykh, K Huang, BM Gunn, A Bryan, ...
Immunity 49 (2), 363-374. e10, 2018
782018
Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein
JJ Mousa, MF Sauer, AM Sevy, JA Finn, JT Bates, G Alvarado, HG King, ...
Proceedings of the National Academy of Sciences 113 (44), E6849-E6858, 2016
482016
Design of protein multi-specificity using an independent sequence search reduces the barrier to low energy sequences
AM Sevy, TM Jacobs, JE Crowe Jr, J Meiler
PLoS computational biology 11 (7), e1004300, 2015
482015
Epitope mapping of inhibitory antibodies targeting the C2 domain of coagulation factor VIII by hydrogen–deuterium exchange mass spectrometry
AM Sevy, JF Healey, W Deng, PC Spiegel, SL Meeks, R Li
Journal of Thrombosis and Haemostasis 11 (12), 2128-2136, 2013
482013
Modeling immunity with Rosetta: methods for antibody and antigen design
CT Schoeder, S Schmitz, J Adolf-Bryfogle, AM Sevy, JA Finn, MF Sauer, ...
Biochemistry 60 (11), 825-846, 2021
392021
Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses
AM Sevy, NC Wu, IM Gilchuk, EH Parrish, S Burger, D Yousif, MBM Nagel, ...
Proceedings of the National Academy of Sciences 116 (5), 1597-1602, 2019
272019
Antibodies: Computer‐aided prediction of structure and design of function
AM Sevy, J Meiler
Antibodies for Infectious Diseases, 173-190, 2015
252015
Computationally designed cyclic peptides derived from an antibody loop increase breadth of binding for influenza variants
AM Sevy, IM Gilchuk, BP Brown, NG Bozhanova, R Nargi, M Jensen, ...
Structure 28 (10), 1114-1123. e4, 2020
242020
Multi-state design of flexible proteins predicts sequences optimal for conformational change
MF Sauer, AM Sevy, JE Crowe Jr, J Meiler
PLOS Computational Biology 16 (2), e1007339, 2020
232020
Discovery of Marburg virus neutralizing antibodies from virus-naïve human antibody repertoires using large-scale structural predictions
NG Bozhanova, AK Sangha, AM Sevy, P Gilchuk, K Huang, RS Nargi, ...
Proceedings of the National Academy of Sciences 117 (49), 31142-31148, 2020
172020
Structure-and sequence-based design of synthetic single-domain antibody libraries
AM Sevy, MT Chen, M Castor, T Sylvia, H Krishnamurthy, A Ishchenko, ...
Protein Engineering, Design and Selection 33, gzaa028, 2020
152020
Integrating linear optimization with structural modeling to increase HIV neutralization breadth
AM Sevy, S Panda, JE Crowe Jr, J Meiler, Y Vorobeychik
PLoS computational biology 14 (2), e1005999, 2018
152018
Identification of structurally related antibodies in antibody sequence databases using rosetta-derived position-specific scoring
JA Finn, J Dong, AM Sevy, E Parrish, I Gilchuk, R Nargi, M Scarlett-Jones, ...
Structure 28 (10), 1124-1130. e5, 2020
102020
Immune repertoire fingerprinting by principal component analysis reveals shared features in subject groups with common exposures
AM Sevy, C Soto, RG Bombardi, J Meiler, JE Crowe
BMC bioinformatics 20, 1-10, 2019
82019
Cooperative Binding Of Anti-Factor VIII Inhibitors and Induced Conformational Change Detected By Hydrogen-Deuterium Exchange Mass Spectrometry
SL Meeks, AM Sevy, JF Healey, W Deng, PC Spiegel, R Li
Blood 122 (21), 1088, 2013
22013
ErrorX: automated error correction for immune repertoire sequencing datasets
AM Sevy
bioRxiv, 2020.02. 17.952408, 2020
12020
Binding proteins and antigen binding fragments thereof that bind abeta
AM Sevy, MT Chen
US Patent App. 18/245,563, 2023
2023
The system can't perform the operation now. Try again later.
Articles 1–20