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Timothy J. Merkel
Timothy J. Merkel
University of North Carolina at Chapel Hill and Northwestern University
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Year
Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence
AB Chinen, CM Guan, JR Ferrer, SN Barnaby, TJ Merkel, CA Mirkin
Chemical reviews 115 (19), 10530-10574, 2015
10212015
Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles
TJ Merkel, SW Jones, KP Herlihy, FR Kersey, AR Shields, M Napier, ...
Proceedings of the National Academy of Sciences 108 (2), 586-591, 2011
6112011
Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastoma
SA Jensen, ES Day, CH Ko, LA Hurley, JP Luciano, FM Kouri, TJ Merkel, ...
Science translational medicine 5 (209), 209ra152-209ra152, 2013
5882013
Immunomodulatory spherical nucleic acids
AF Radovic-Moreno, N Chernyak, CC Mader, S Nallagatla, RS Kang, ...
Proceedings of the National Academy of Sciences 112 (13), 3892-3897, 2015
2792015
Scalable, shape-specific, top-down fabrication methods for the synthesis of engineered colloidal particles
TJ Merkel, KP Herlihy, J Nunes, RM Orgel, JP Rolland, JM DeSimone
Langmuir 26 (16), 13086-13096, 2010
2782010
miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma
FM Kouri, LA Hurley, WL Daniel, ES Day, Y Hua, L Hao, CY Peng, ...
Genes & development 29 (7), 732-745, 2015
2242015
One-step syntheses of photocurable polyesters based on a renewable resource
DG Barrett, TJ Merkel, JC Luft, MN Yousaf
Macromolecules 43 (23), 9660-9667, 2010
1492010
The effect of particle size on the biodistribution of low-modulus hydrogel PRINT particles
TJ Merkel, K Chen, SW Jones, AA Pandya, S Tian, ME Napier, ...
Journal of controlled release 162 (1), 37-44, 2012
1232012
Biocompatible infinite‐coordination‐polymer nanoparticle–nucleic‐acid conjugates for antisense gene regulation
CM Calabrese, TJ Merkel, WE Briley, PS Randeria, SP Narayan, ...
Angewandte Chemie 127 (2), 486-490, 2015
1022015
Low modulus biomimetic microgel particles with high loading of hemoglobin
K Chen, TJ Merkel, A Pandya, ME Napier, JC Luft, W Daniel, S Sheiko, ...
Biomacromolecules 13 (9), 2748-2759, 2012
932012
Effect of aspect ratio and deformability on nanoparticle extravasation through nanopores
FR Kersey, TJ Merkel, JL Perry, ME Napier, JM DeSimone
Langmuir 28 (23), 8773-8781, 2012
832012
Amphiphilic co-networks with moisture-induced surface segregation for high-performance nonfouling coatings
Y Wang, JA Finlay, DE Betts, TJ Merkel, JC Luft, ME Callow, JA Callow, ...
Langmuir 27 (17), 10365-10369, 2011
792011
Dual bioluminescence and near-infrared fluorescence monitoring to evaluate spherical nucleic acid nanoconjugate activity in vivo
TL Sita, FM Kouri, LA Hurley, TJ Merkel, A Chalastanis, JL May, ST Ghelfi, ...
Proceedings of the National Academy of Sciences 114 (16), 4129-4134, 2017
552017
Generation of a library of particles having controlled sizes and shapes via the mechanical elongation of master templates
Y Wang, TJ Merkel, K Chen, CA Fromen, DE Betts, JM DeSimone
Langmuir 27 (2), 524-528, 2011
522011
Dodging drug-resistant cancer with diamonds
TJ Merkel, JM DeSimone
Science translational medicine 3 (73), 73ps8-73ps8, 2011
502011
Tunneling characteristics of Au–alkanedithiol–Au junctions formed via nanotransfer printing (nTP)
JR Niskala, WC Rice, RC Bruce, TJ Merkel, F Tsui, W You
Journal of the American Chemical Society 134 (29), 12072-12082, 2012
452012
Relationships between poly (ethylene glycol) modifications on RNA–spherical nucleic acid conjugates and cellular uptake and circulation time
AB Chinen, JR Ferrer, TJ Merkel, CA Mirkin
Bioconjugate chemistry 27 (11), 2715-2721, 2016
332016
Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastoma
SA Jensen, ES Day, CH Ko, LA Hurley, JP Luciano, FM Kouri, TJ Merkel, ...
Spherical nucleic acids, 1625-1648, 2020
22020
Soft lithography-based hydrogel particles and the effect of shape and size on biodistribution
K Herlihy, T Merkel, H An, W Lin, J DeSimone
Nanotechnology 2009: Life Sciences, Medicine, Diagnostics, Bio Materials and …, 2009
22009
Self-manageable abnormal scar treatment with spherical nucleic acid (sna) technology
CA Mirkin, AJ Sprangers, S Zhu, AJ Ponedal, TJ Merkel, SP Narayan
US Patent App. 17/054,441, 2021
12021
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