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Aimee Shen
Aimee Shen
Assistant Professor, Tufts University School of Medicine
Подтвержден адрес электронной почты в домене tufts.edu
Название
Процитировано
Процитировано
Год
A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus
JD Mougous, ME Cuff, S Raunser, A Shen, M Zhou, CA Gifford, ...
Science 312 (5779), 1526-1530, 2006
11272006
Clostridium difficile spore biology: sporulation, germination, and spore structural proteins
D Paredes-Sabja, A Shen, JA Sorg
Trends in microbiology 22 (7), 406-416, 2014
4002014
Global Analysis of the Sporulation Pathway of Clostridium difficile
KA Fimlaid, JP Bond, KC Schutz, EE Putnam, JM Leung, TD Lawley, ...
PLoS genetics 9 (8), e1003660, 2013
1872013
Synthetic riboswitches that induce gene expression in diverse bacterial species
S Topp, CMK Reynoso, JC Seeliger, IS Goldlust, SK Desai, D Murat, ...
Applied and environmental microbiology 76 (23), 7881-7884, 2010
1852010
Clostridium difficile toxins: mediators of inflammation
A Shen
Journal of innate immunity 4 (2), 149-158, 2012
1722012
A bifunctional O-GlcNAc transferase governs flagellar motility through anti-repression
A Shen, HD Kamp, A Gründling, DE Higgins
Genes & Development 20 (23), 3283-3295, 2006
1342006
The MogR transcriptional repressor regulates nonhierarchal expression of flagellar motility genes and virulence in Listeria monocytogenes
A Shen, DE Higgins
PLoS pathogens 2 (4), e30, 2006
1322006
Small molecule-induced allosteric activation of the Vibrio cholerae RTX cysteine protease domain
PJ Lupardus, A Shen, M Bogyo, KC Garcia
science 322 (5899), 265-268, 2008
1302008
The 5′ untranslated region‐mediated enhancement of intracellular listeriolysin O production is required for Listeria monocytogenes pathogenicity
A Shen, DE Higgins
Molecular microbiology 57 (5), 1460-1473, 2005
1242005
A small-molecule antivirulence agent for treating Clostridium difficile infection
KO Bender, M Garland, JA Ferreyra, AJ Hryckowian, MA Child, AW Puri, ...
Science translational medicine 7 (306), 306ra148-306ra148, 2015
1192015
SpoIVA and SipL are Clostridium difficile spore morphogenetic proteins
EE Putnam, AM Nock, TD Lawley, A Shen
Journal of bacteriology 195 (6), 1214-1225, 2013
1112013
Structural and Functional Analysis of the CspB Protease Required for Clostridium Spore Germination
CM Adams, BE Eckenroth, EE Putnam, S Doublié, A Shen
PLoS pathogens 9 (2), e1003165, 2013
1112013
Diverse mechanisms regulate sporulation sigma factor activity in the Firmicutes
KA Fimlaid, A Shen
Current opinion in microbiology 24, 88-95, 2015
1102015
Simplified, enhanced protein purification using an inducible, autoprocessing enzyme tag
A Shen, PJ Lupardus, M Morell, EL Ponder, AM Sadaghiani, KC Garcia, ...
PloS one 4 (12), e8119, 2009
942009
Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins
A Shen, PJ Lupardus, MM Gersch, AW Puri, VE Albrow, KC Garcia, ...
Nature structural & molecular biology 18 (3), 364-371, 2011
902011
Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin
A Shen, PJ Lupardus, VE Albrow, A Guzzetta, JC Powers, KC Garcia, ...
Nature chemical biology 5 (7), 469-478, 2009
862009
Rational design of inhibitors and activity-based probes targeting Clostridium difficile virulence factor TcdB
AW Puri, PJ Lupardus, E Deu, VE Albrow, KC Garcia, M Bogyo, A Shen
Chemistry & biology 17 (11), 1201-1211, 2010
742010
Caspase-1 activity is required to bypass macrophage apoptosis upon Salmonella infection
AW Puri, P Broz, A Shen, DM Monack, M Bogyo
Nature chemical biology 8 (9), 745-747, 2012
702012
Regulation of Clostridium difficile spore germination by the CspA pseudoprotease domain
Y Kevorkian, DJ Shirley, A Shen
Biochimie 122, 243-254, 2016
622016
Characterization of the dynamic germination of individual Clostridium difficile spores using Raman spectroscopy and differential interference contrast microscopy
S Wang, A Shen, P Setlow, Y Li
Journal of bacteriology 197 (14), 2361-2373, 2015
622015
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Статьи 1–20