Direct detection of early-stage cancers using circulating tumor DNA J Phallen, M Sausen, V Adleff, A Leal, C Hruban, J White, V Anagnostou, ... Science translational medicine 9 (403), eaan2415, 2017 | 1035 | 2017 |
Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients M Sausen, J Phallen, V Adleff, S Jones, RJ Leary, MT Barrett, ... Nature communications 6 (1), 7686, 2015 | 475 | 2015 |
Personalized genomic analyses for cancer mutation discovery and interpretation S Jones, V Anagnostou, K Lytle, S Parpart-Li, M Nesselbush, DR Riley, ... Science translational medicine 7 (283), 283ra53-283ra53, 2015 | 470 | 2015 |
MicroRNA-184 inhibits neuroblastoma cell survival through targeting the serine/threonine kinase AKT2 NH Foley, IM Bray, A Tivnan, K Bryan, DM Murphy, PG Buckley, J Ryan, ... Molecular cancer 9, 1-11, 2010 | 192 | 2010 |
MiRNA-335 suppresses neuroblastoma cell invasiveness by direct targeting of multiple genes from the non-canonical TGF-β signalling pathway J Lynch, J Fay, M Meehan, K Bryan, KM Watters, DM Murphy, RL Stallings Carcinogenesis 33 (5), 976-985, 2012 | 177 | 2012 |
Widespread dysregulation of MiRNAs by MYCN amplification and chromosomal imbalances in neuroblastoma: association of miRNA expression with survival I Bray, K Bryan, S Prenter, PG Buckley, NH Foley, DM Murphy, L Alcock, ... PloS one 4 (11), e7850, 2009 | 143 | 2009 |
MicroRNA mediates DNA demethylation events triggered by retinoic acid during neuroblastoma cell differentiation S Das, N Foley, K Bryan, KM Watters, I Bray, DM Murphy, PG Buckley, ... Cancer research 70 (20), 7874-7881, 2010 | 132 | 2010 |
Noninvasive detection of microsatellite instability and high tumor mutation burden in cancer patients treated with PD-1 blockade A Georgiadis, JN Durham, LA Keefer, BR Bartlett, M Zielonka, D Murphy, ... Clinical Cancer Research 25 (23), 7024-7034, 2019 | 121 | 2019 |
Global MYCN transcription factor binding analysis in neuroblastoma reveals association with distinct E-box motifs and regions of DNA hypermethylation DM Murphy, PG Buckley, K Bryan, S Das, L Alcock, NH Foley, S Prenter, ... PloS one 4 (12), e8154, 2009 | 92 | 2009 |
NRAS mutations with low allele burden have independent prognostic significance for patients with lower risk myelodysplastic syndromes DM Murphy, R Bejar, K Stevenson, D Neuberg, Y Shi, C Cubrich, ... Leukemia 27 (10), 2077-2081, 2013 | 66 | 2013 |
Dissection of the oncogenic MYCN transcriptional network reveals a large set of clinically relevant cell cycle genes as drivers of neuroblastoma tumorigenesis DM Murphy, PG Buckley, K Bryan, KM Watters, J Koster, P van Sluis, ... Molecular carcinogenesis 50 (6), 403-411, 2011 | 33 | 2011 |
Co-localization of the oncogenic transcription factor MYCN and the DNA methyl binding protein MeCP2 at genomic sites in neuroblastoma DM Murphy, PG Buckley, S Das, KM Watters, K Bryan, RL Stallings PLoS One 6 (6), e21436, 2011 | 29 | 2011 |
MYCN repression of Lifeguard/FAIM2 enhances neuroblastoma aggressiveness L Planells-Ferrer, J Urresti, A Soriano, S Reix, DM Murphy, JC Ferreres, ... Cell death & disease 5 (9), e1401-e1401, 2014 | 23 | 2014 |
A non-invasive liquid biopsy approach for therapeutic stratification of lung cancer patients. H Husain, J Phallen, S Parpart-Li, DM Murphy, V Adleff, SV Angiuoli, ... Journal of Clinical Oncology 33 (15_suppl), e19082-e19082, 2015 | 4 | 2015 |
Circulating tumor DNA (ctDNA) as a prognostic marker for recurrence in resected pancreas cancer. JSZ Wang, M Sausen, S Parpart-Li, DM Murphy, VE Velculescu, LD Wood, ... Journal of Clinical Oncology 33 (15_suppl), 11025-11025, 2015 | 3 | 2015 |
A comprehensive noninvasive approach for the stratification of lung cancer patients for targeted therapies. DM Murphy, SV Angiuoli, B Chesnick, K Galens, S Jones, M Kadan, ... Journal of Clinical Oncology 33 (15_suppl), e22086-e22086, 2015 | 2 | 2015 |
Personalized Genomic Analyses for Cancer Mutation Discovery and Interpretation. V Anagnostou, S Jones, K Lytle, S Parpart-Li, M Nesselbush, V Adleff, ... Journal of Clinical Oncology 33 (15_suppl), 1529-1529, 2015 | 1 | 2015 |
A method for comprehensive genomic analysis of cell-free DNA. S Parpart-Li, SV Angiuoli, B Chesnick, K Galens, S Jones, M Kadan, ... Journal of Clinical Oncology 33 (15_suppl), e22070-e22070, 2015 | 1 | 2015 |
Clinical validation of a cell-free DNA liquid biopsy approach for noninvasive molecular profiling M Nesselbush, S Angiuoli, LA Diaz, A Georgiadis, S Glynn, S Jones, ... Cancer Research 77 (13_Supplement), 4954-4954, 2017 | | 2017 |
Noninvasive detection of MET gene amplification in the circulation of cancer patients M Sausen, SV Angiuoli, B Chesnick, K Galens, S Jones, M Kadan, L Kann, ... Cancer Research 75 (15_Supplement), 5246-5246, 2015 | | 2015 |