Flavia Squeglia
Flavia Squeglia
Institute of Biostructure and Bioimaging (IBB) of the Italian National Research
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A structural view of SARS-CoV-2 RNA replication machinery: RNA synthesis, proofreading and final capping
M Romano, A Ruggiero, F Squeglia, G Maga, R Berisio
Cells 9 (5), 1267, 2020
Chitin-induced activation of immune signaling by the rice receptor CEBiP relies on a unique sandwich-type dimerization
M Hayafune, R Berisio, R Marchetti, A Silipo, M Kayama, Y Desaki, ...
Proceedings of the National Academy of Sciences 111 (3), E404-E413, 2014
Chemical basis of peptidoglycan discrimination by PrkC, a key kinase involved in bacterial resuscitation from dormancy
F Squeglia, R Marchetti, A Ruggiero, R Lanzetta, D Marasco, J Dworkin, ...
Journal of the American Chemical Society 133 (51), 20676-20679, 2011
Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation
A Ruggiero, D Marasco, F Squeglia, S Soldini, E Pedone, C Pedone, ...
Structure 18 (9), 1184-1190, 2010
Capsule-Targeting Depolymerase, Derived from Klebsiella KP36 Phage, as a Tool for the Development of Anti-Virulent Strategy
G Majkowska-Skrobek, A Łątka, R Berisio, B Maciejewska, F Squeglia, ...
Viruses 8 (12), 324, 2016
Phage-borne depolymerases decrease Klebsiella pneumoniae resistance to innate defense mechanisms
G Majkowska-Skrobek, A Latka, R Berisio, F Squeglia, B Maciejewska, ...
Frontiers in Microbiology 9, 419180, 2018
Bacterial cell division regulation by Ser/Thr kinases: a structural perspective
A Ruggiero, P De Simone, G Smaldone, F Squeglia, R Berisio
Current Protein and Peptide Science 13 (8), 756-766, 2012
X-ray structural studies of the entire extracellular region of the serine/threonine kinase PrkC from Staphylococcus aureus
A Ruggiero, F Squeglia, D Marasco, R Marchetti, A Molinaro, R Berisio
Biochemical Journal 435 (1), 33-41, 2011
Collagen‐like proteins of pathogenic streptococci
S Lukomski, BA Bachert, F Squeglia, R Berisio
Molecular microbiology 103 (6), 919-930, 2017
Chemistry of Peptidoglycan in Mycobacterium tuberculosis Life Cycle: An off‐the‐wall Balance of Synthesis and Degradation
F Squeglia, A Ruggiero, R Berisio
Chemistry–A European Journal 24 (11), 2533-2546, 2018
Carbohydrate recognition by RpfB from Mycobacterium tuberculosis unveiled by crystallographic and molecular dynamics analyses
F Squeglia, M Romano, A Ruggiero, L Vitagliano, A De Simone, R Berisio
Biophysical journal 104 (11), 2530-2539, 2013
Structural and functional studies of a Klebsiella phage capsule depolymerase tailspike: mechanistic insights into capsular degradation
F Squeglia, B Maciejewska, A Łątka, A Ruggiero, Y Briers, Z Drulis-Kawa, ...
Structure 28 (6), 613-624. e4, 2020
Molecular determinants of inactivation of the resuscitation promoting factor B from Mycobacterium tuberculosis
A Ruggiero, J Marchant, F Squeglia, V Makarov, A De Simone, R Berisio
Journal of Biomolecular Structure and Dynamics 31 (2), 195-205, 2013
The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group A Streptococcus shows significant similarity to immunomodulatory …
F Squeglia, B Bachert, A De Simone, S Lukomski, R Berisio
Journal of Biological Chemistry 289 (8), 5122-5133, 2014
Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis
L Calvanese, L Falcigno, C Maglione, D Marasco, A Ruggiero, F Squeglia, ...
Biopolymers 101 (7), 712-719, 2014
The structure of Resuscitation promoting factor B from M. tuberculosis reveals unexpected ubiquitin-like domains
A Ruggiero, F Squeglia, M Romano, L Vitagliano, A De Simone, R Berisio
Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (2), 445-451, 2016
Host DDX helicases as possible SARS-CoV-2 proviral factors: a structural overview of their hijacking through multiple viral proteins
F Squeglia, M Romano, A Ruggiero, G Maga, R Berisio
Frontiers in chemistry 8, 602162, 2020
Collagen degradation in tuberculosis pathogenesis: the biochemical consequences of hosting an undesired guest
F Squeglia, A Ruggiero, R Berisio
Biochemical Journal 475 (19), 3123-3140, 2018
A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics
F Squeglia, A Ruggiero, A De Simone, R Berisio
Protein Science 27 (2), 369-380, 2018
Mutational and structural study of RipA, a key enzyme in Mycobacterium tuberculosis cell division: evidence for the L-to-D inversion of configuration of the catalytic cysteine
F Squeglia, A Ruggiero, M Romano, L Vitagliano, R Berisio
Acta Crystallographica Section D: Biological Crystallography 70 (9), 2295-2300, 2014
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