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Andrew Karaplis
Andrew Karaplis
Verified email at mcgill.ca
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Year
PTH/PTHrP receptor in early development and Indian hedgehog—regulated bone growth
B Lanske, AC Karaplis, K Lee, A Luz, A Vortkamp, A Pirro, M Karperien, ...
Science 273 (5275), 663-666, 1996
14951996
Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene.
AC Karaplis, A Luz, J Glowacki, RT Bronson, VL Tybulewicz, ...
Genes & development 8 (3), 277-289, 1994
13101994
Romosozumab or alendronate for fracture prevention in women with osteoporosis
KG Saag, J Petersen, ML Brandi, AC Karaplis, M Lorentzon, T Thomas, ...
New England Journal of Medicine 377 (15), 1417-1427, 2017
11272017
Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition
Z Chen, AC Karaplis, SL Ackerman, IP Pogribny, S Melnyk, ...
Human molecular genetics 10 (5), 433-444, 2001
7712001
Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities
L Beck, AC Karaplis, N Amizuka, AS Hewson, H Ozawa, HS Tenenhouse
Proceedings of the National Academy of Sciences 95 (9), 5372-5377, 1998
6631998
Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation.
N Amizuka, H Warshawsky, JE Henderson, D Goltzman, AC Karaplis
The Journal of cell biology 126 (6), 1611-1623, 1994
5611994
Nucleolar localization of parathyroid hormone-related peptide enhances survival of chondrocytes under conditions that promote apoptotic cell death
JE Henderson, N Amizuka, H Warshawsky, D Biasotto, BMK Lanske, ...
Molecular and cellular biology, 1995
3871995
Transgenic mice overexpressing human fibroblast growth factor 23 (R176Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders
X Bai, D Miao, J Li, D Goltzman, AC Karaplis
Endocrinology 145 (11), 5269-5279, 2004
3832004
Parathyroid hormone-related peptide (PTHrP) regulates fetal–placental calcium transport through a receptor distinct from the PTH/PTHrP receptor
CS Kovacs, B Lanske, JL Hunzelman, J Guo, AC Karaplis, ...
Proceedings of the National Academy of Sciences 93 (26), 15233-15238, 1996
3501996
Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development
K Lee, B Lanske, AC Karaplis, JD Deeds, H Kohno, RA Nissenson, ...
Endocrinology 137 (11), 5109-5118, 1996
3461996
Osteoblast-derived PTHrP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1–34
D Miao, B He, Y Jiang, T Kobayashi, MA Sorocéanu, J Zhao, H Su, ...
The Journal of clinical investigation 115 (9), 2402-2411, 2005
3332005
Parathyroid hormone is essential for normal fetal bone formation
D Miao, B He, AC Karaplis, D Goltzman
The Journal of clinical investigation 109 (9), 1173-1182, 2002
3272002
Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development
JJ Wysolmerski, WM Philbrick, ME Dunbar, B Lanske, H Kronenberg, ...
Development 125 (7), 1285-1294, 1998
3141998
Parathyroid hormone-related protein is required for tooth eruption
WM Philbrick, BE Dreyer, IA Nakchbandi, AC Karaplis
Proceedings of the National Academy of Sciences 95 (20), 11846-11851, 1998
3101998
The autosomal dominant hypophosphatemic rickets R176Q mutation in fibroblast growth factor 23 resists proteolytic cleavage and enhances in vivo biological potency
XY Bai, D Miao, D Goltzman, AC Karaplis
Journal of Biological Chemistry 278 (11), 9843-9849, 2003
2972003
Haploinsufficiency of parathyroid hormone-related peptide (PTHrP) results in abnormal postnatal bone development
N Amizuka, AC Karaplis, JE Henderson, H Warshawsky, ML Lipman, ...
Developmental biology 175 (1), 166-176, 1996
2651996
Rosiglitazone impacts negatively on bone by promoting osteoblast/osteocyte apoptosis
MA Sorocéanu, D Miao, XY Bai, H Su, D Goltzman, AC Karaplis
Journal of Endocrinology 183 (1), 203-216, 2004
2562004
Bisphosphonates for treatment of osteoporosis: expected benefits, potential harms, and drug holidays
JP Brown, S Morin, W Leslie, A Papaioannou, AM Cheung, KS Davison, ...
Canadian Family Physician 60 (4), 324-333, 2014
2452014
The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone
CH Kos, AC Karaplis, JB Peng, MA Hediger, D Goltzman, KS Mohammad, ...
The Journal of clinical investigation 111 (7), 1021-1028, 2003
2392003
Identical complementary deoxyribonucleic acids encode a human renal and bone parathyroid hormone (PTH)/PTH-related peptide receptor
E Schipani, H Karga, AC Karaplis, JT Potts Jr, HM Kronenberg, GV Segre, ...
Endocrinology 132 (5), 2157-2165, 1993
2361993
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