Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor JC Rodríguez-Manzaneque, TF Lane, MA Ortega, RO Hynes, J Lawler, ... Proceedings of the National Academy of Sciences 98 (22), 12485-12490, 2001 | 565 | 2001 |
Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4 JD Sandy, J Westling, RD Kenagy, ML Iruela-Arispe, C Verscharen, ... Journal of Biological Chemistry 276 (16), 13372-13378, 2001 | 522 | 2001 |
ADAMTS1 cleaves aggrecan at multiple sites and is differentially inhibited by metalloproteinase inhibitors JC Rodrı́guez-Manzaneque, J Westling, SNM Thai, A Luque, V Knauper, ... Biochemical and biophysical research communications 293 (1), 501-508, 2002 | 290 | 2002 |
Characterization of METH-1/ADAMTS1 processing reveals two distinct active forms JC Rodrı́guez-Manzaneque, AB Milchanowski, EK Dufour, R Leduc, ... Journal of Biological Chemistry 275 (43), 33471-33479, 2000 | 192 | 2000 |
Progesterone regulates proliferation of endothelial cells F Vázquez, JC Rodrı́guez-Manzaneque, JP Lydon, DP Edwards, ... Journal of Biological Chemistry 274 (4), 2185-2192, 1999 | 180 | 1999 |
Tumor angiogenesis and vascular patterning: a mathematical model RDM Travasso, E Corvera Poiré, M Castro, JC Rodrguez-Manzaneque, ... PloS one 6 (5), e19989, 2011 | 164 | 2011 |
PARP-1 regulates metastatic melanoma through modulation of vimentin-induced malignant transformation MI Rodríguez, A Peralta-Leal, F O'Valle, JM Rodriguez-Vargas, ... PLoS genetics 9 (6), e1003531, 2013 | 155 | 2013 |
Tumour angiogenesis is reduced in the Tc1 mouse model of Down’s syndrome LE Reynolds, AR Watson, M Baker, TA Jones, G D’Amico, SD Robinson, ... Nature 465 (7299), 813-817, 2010 | 154 | 2010 |
Perinatal hypothyroidism impairs the normal transition of GLUT4 and GLUT1 glucose transporters from fetal to neonatal levels in heart and brown adipose tissue. Evidence for … A Castelló, JC Rodríguez-Manzaneque, M Camps, A Perez-Castillo, ... Journal of biological chemistry 269 (8), 5905-5912, 1994 | 141 | 1994 |
Endometrial endothelial cells express estrogen and progesterone receptors and exhibit a tissue specific response to angiogenic growth factors ML IRUELA‐ARISPE, JC RODRIGUEZ‐MANZANEQUE, ... Microcirculation 6 (2), 127-140, 1999 | 133 | 1999 |
Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1 NV Lee, JC Rodriguez-Manzaneque, SNM Thai, WO Twal, A Luque, ... Journal of Biological Chemistry 280 (41), 34796-34804, 2005 | 118 | 2005 |
The cleavage of semaphorin 3C induced by ADAMTS1 promotes cell migration C Esselens, J Malapeira, N Colomé, C Casal, JC Rodríguez-Manzaneque, ... Journal of biological chemistry 285 (4), 2463-2473, 2010 | 112 | 2010 |
Cleavage of syndecan-4 by ADAMTS1 provokes defects in adhesion JC Rodríguez-Manzaneque, D Carpizo, M del Carmen Plaza-Calonge, ... The international journal of biochemistry & cell biology 41 (4), 800-810, 2009 | 99 | 2009 |
ADAMTS1 interacts with, cleaves, and modifies the extracellular location of the matrix inhibitor tissue factor pathway inhibitor-2 AX Torres-Collado, W Kisiel, ML Iruela-Arispe, ... Journal of Biological Chemistry 281 (26), 17827-17837, 2006 | 78 | 2006 |
The force at the tip-modelling tension and proliferation in sprouting angiogenesis P Santos-Oliveira, A Correia, T Rodrigues, TM Ribeiro-Rodrigues, ... PLoS computational biology 11 (8), e1004436, 2015 | 71 | 2015 |
Identification of substrates of the extracellular protease ADAMTS1 by DIGE proteomic analysis F Canals, N Colomé, C Ferrer, MC Plaza‐Calonge, ... Proteomics 6 (S1), S28-S35, 2006 | 71 | 2006 |
ADAMTS proteases in vascular biology JC Rodríguez-Manzaneque, R Fernández-Rodríguez, ... Matrix Biology 44, 38-45, 2015 | 63 | 2015 |
A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification C Bueno, R Montes, GJ Melen, V Ramos-Mejia, PJ Real, V Ayllón, ... Cell research 22 (6), 986-1002, 2012 | 61 | 2012 |
ADAMTS1 contributes to the acquisition of an endothelial-like phenotype in plastic tumor cells C Casal, AX Torres-Collado, M del Carmen Plaza-Calonge, ... Cancer research 70 (11), 4676-4686, 2010 | 56 | 2010 |
Changes in tyrosine hydroxylase gene expression in mesencephalic catecholaminergic neurons of immature and adult male rats perinatally exposed to cannabinoids A Bonnin, R De Miguel, JC Rodriguez-Manzaneque, JJ Fernandez-Ruiz, ... Developmental brain research 81 (1), 147-150, 1994 | 50 | 1994 |