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Sergey Brezgin
Sergey Brezgin
First Moscow State Medical University, Moscow, Russia
Verified email at staff.sechenov.ru
Title
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Cited by
Year
Dead Cas systems: types, principles, and applications
S Brezgin, A Kostyusheva, D Kostyushev, V Chulanov
International journal of molecular sciences 20 (23), 6041, 2019
982019
CRISPR-Cas systems for diagnosing infectious diseases
A Kostyusheva, S Brezgin, Y Babin, I Vasilyeva, D Glebe, D Kostyushev, ...
Methods 203, 431-446, 2022
732022
Orthologous CRISPR/Cas9 systems for specific and efficient degradation of covalently closed circular DNA of hepatitis B virus
D Kostyushev, S Brezgin, A Kostyusheva, D Zarifyan, I Goptar, ...
Cellular and molecular life sciences 76 (9), 1779-1794, 2019
652019
Suppressing the NHEJ pathway by DNA-PKcs inhibitor NU7026 prevents degradation of HBV cccDNA cleaved by CRISPR/Cas9
D Kostyushev, A Kostyusheva, S Brezgin, D Zarifyan, A Utkina, I Goptar, ...
Scientific reports 9 (1), 1847, 2019
462019
Gene editing by extracellular vesicles
D Kostyushev, A Kostyusheva, S Brezgin, V Smirnov, E Volchkova, ...
International Journal of Molecular Sciences 21 (19), 7362, 2020
342020
Host-cell interactions in HBV infection and pathogenesis: the emerging role of m6A modification
A Kostyusheva, S Brezgin, D Glebe, D Kostyushev, V Chulanov
Emerging Microbes & Infections 10 (1), 2264-2275, 2021
322021
Small molecular inhibitors of DNA double strand break repair pathways increase the ANTI-HBV activity of CRISPR/Cas9
AP Kostyusheva, DS Kostyushev, SA Brezgin, DN Zarifyan, EV Volchkova, ...
Molecular Biology 53, 274-285, 2019
192019
Biomimetic approaches for targeting tumor-promoting inflammation
A Parodi, D Kostyushev, S Brezgin, A Kostyusheva, T Borodina, R Akasov, ...
Seminars in Cancer Biology 86, 555-567, 2022
172022
ATM and ATR expression potentiates HBV replication and contributes to reactivation of HBV infection upon DNA damage
A Kostyusheva, S Brezgin, E Bayurova, I Gordeychuk, M Isaguliants, ...
Viruses 11 (11), 997, 2019
172019
Clinical implications of hepatitis B virus RNA and covalently closed circular DNA in monitoring patients with chronic hepatitis B today with a gaze into the future: the field …
A Kostyusheva, D Kostyushev, S Brezgin, E Volchkova, V Chulanov
Genes 9 (10), 483, 2018
172018
Replenishment of hepatitis B virus cccDNA pool is restricted by baseline expression of host restriction factors in vitro
S Brezgin, A Kostyusheva, E Bayurova, I Gordeychuk, M Isaguliants, ...
Microorganisms 7 (11), 533, 2019
122019
Immunity and viral infections: modulating antiviral response via CRISPR–Cas systems
S Brezgin, A Kostyusheva, E Bayurova, E Volchkova, V Gegechkori, ...
Viruses 13 (7), 1373, 2021
112021
Technological aspects of manufacturing and analytical control of biological nanoparticles
S Brezgin, A Parodi, A Kostyusheva, N Ponomareva, A Lukashev, ...
Biotechnology Advances 64, 108122, 2023
82023
Overexpression of DNA-methyltransferases in persistency of cccDNA pool in chronic hepatitis B
DS Kostyushev, AP Zueva, SA Brezgin, AD Lipatnikov, VN Simirskii, ...
Terapevticheskii arkhiv 89 (11), 21-26, 2017
82017
Depleting hepatitis B virus relaxed circular DNA is necessary for resolution of infection by CRISPR-Cas9
D Kostyushev, A Kostyusheva, S Brezgin, N Ponomareva, NF Zakirova, ...
Molecular Therapy-Nucleic Acids 31, 482-493, 2023
72023
CRISPR screening: Molecular tools for studying virus–host interactions
V Chulanov, A Kostyusheva, S Brezgin, N Ponomareva, V Gegechkori, ...
Viruses 13 (11), 2258, 2021
72021
Clearing of foreign episomal DNA from human cells by CRISPRa-mediated activation of cytidine deaminases
S Brezgin, A Kostyusheva, N Ponomareva, V Volia, I Goptar, A Nikiforova, ...
International journal of molecular sciences 21 (18), 6865, 2020
72020
Previous hepatitis B viral infection–an underestimated cause of pancreatic cancer
S Batskikh, S Morozov, A Dorofeev, Z Borunova, D Kostyushev, S Brezgin, ...
World Journal of Gastroenterology 28 (33), 4812, 2022
52022
Hepatitis C can be cured: will hepatitis B become next?
VP Chulanov, AP Zueva, DS Kostyushev, SA Brezgin, EV Volchkova, ...
Terapevticheskii arkhiv 89 (11), 4-13, 2017
52017
CRISPR/Cas and hepatitis B therapy: technological advances and practical barriers
D Kostyushev, A Kostyusheva, N Ponomareva, S Brezgin, V Chulanov
nucleic acid therapeutics 32 (1), 14-28, 2022
42022
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