Aishwarya Prakash
Aishwarya Prakash
Assistant Professor, Mitchell Cancer Institute
Подтвержден адрес электронной почты в домене - Главная страница
The Fpg/Nei family of DNA glycosylases: substrates, structures, and search for damage
A Prakash, S Doublié, SS Wallace
Progress in molecular biology and translational science 110, 71-91, 2012
Base excision repair in the mitochondria
A Prakash, S Doublié
Journal of cellular biochemistry 116 (8), 1490-1499, 2015
Human Replication Protein A− Rad52− Single-Stranded DNA Complex: Stoichiometry and Evidence for Strand Transfer Regulation by Phosphorylation
X Deng, A Prakash, K Dhar, GS Baia, C Kolar, GG Oakley, GEO Borgstahl
Biochemistry 48 (28), 6633-6643, 2009
DNA damage related crosstalk between the nucleus and mitochondria
M Saki, A Prakash
Free Radical Biology and Medicine 107, 216-227, 2017
Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: activity, structure, and the effect of editing
A Prakash, BL Carroll, JB Sweasy, SS Wallace, S Doublié
DNA repair 14, 17-26, 2014
Replication protein A (RPA) hampers the processive action of APOBEC3G cytosine deaminase on single-stranded DNA
AG Lada, ISR Waisertreiger, CE Grabow, A Prakash, GEO Borgstahl, ...
PLoS One 6 (9), 2011
Identification of the DNA-binding domains of human replication protein A that recognize G-quadruplex DNA
A Prakash, A Natarajan, LA Marky, MM Ouellette, GEO Borgstahl
Journal of nucleic acids 2011, 2011
The structure and function of replication protein A in DNA replication
A Prakash, GEO Borgstahl
The Eukaryotic Replisome: A Guide to Protein Structure and Function, 171-196, 2012
A germline polymorphism of thymine DNA glycosylase induces genomic instability and cellular transformation
A Sjolund, AA Nemec, N Paquet, A Prakash, P Sung, S Doublié, ...
PLoS genetics 10 (11), 2014
Stabilization of a G-quadruplex from unfolding by replication protein a using potassium and the porphyrin TMPyP4
A Prakash, F Kieken, LA Marky, GEO Borgstahl
Journal of nucleic acids 2011, 2011
Structural investigation of a viral ortholog of human NEIL2/3 DNA glycosylases
A Prakash, BE Eckenroth, AM Averill, K Imamura, SS Wallace, S Doublié
DNA repair 12 (12), 1062-1071, 2013
The changing landscape of Lynch syndrome due to PMS2 mutations
J Blount, A Prakash
Clinical genetics 94 (1), 61-69, 2018
The antitumor drug LB-100 is a catalytic inhibitor of protein phosphatase 2A (PPP2CA) and 5 (PPP5C) coordinating with the active-site catalytic metals in PPP5C
BM D'Arcy, MR Swingle, CM Papke, KA Abney, ES Bouska, A Prakash, ...
Molecular cancer therapeutics 18 (3), 556-566, 2019
The C-terminal tail of the NEIL1 DNA glycosylase interacts with the human mitochondrial single-stranded DNA binding protein
N Sharma, S Chakravarthy, MJ Longley, WC Copeland, A Prakash
DNA repair 65, 11-19, 2018
The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation
HA Galick, CG Marsden, S Kathe, JA Dragon, L Volk, AA Nemec, ...
Oncotarget 8 (49), 85883, 2017
Destabilization of the PCNA trimer mediated by its interaction with the NEIL1 DNA glycosylase
A Prakash, K Moharana, SS Wallace, S Doublié
Nucleic acids research 45 (5), 2897-2909, 2017
Phosphorylation sites identified in the NEIL1 DNA glycosylase are potential targets for the JNK1 kinase
A Prakash, VB Cao, S Doublie
PloS one 11 (8), 2016
Mitochondrial DNA: epigenetics and environment
N Sharma, MS Pasala, A Prakash
Environmental and molecular mutagenesis 60 (8), 668-682, 2019
Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress
Q Fang, J Andrews, N Sharma, A Wilk, J Clark, J Slyskova, CA Koczor, ...
Nucleic acids research 47 (12), 6269-6286, 2019
Biochemical and structural characterization of two variants of uncertain significance in the PMS2 gene
BM D'Arcy, J Blount, A Prakash
Human mutation 40 (4), 458-471, 2019
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