| Radiation and PD-(L) 1 treatment combinations: immune response and dose optimization via a predictive systems model Y Kosinsky, SJ Dovedi, K Peskov, V Voronova, L Chu, H Tomkinson, ... Journal for immunotherapy of cancer 6, 1-15, 2018 | 91 | 2018 |
| The Distinct Functional Properties of the Nucleotide-binding Domain of ATP7B, the Human Copper-transporting ATPase*: ANALYSIS OF THE WILSON DISEASE MUTATIONS E1064A, H1069Q … CT Morgan, R Tsivkovskii, YA Kosinsky, RG Efremov, S Lutsenko Journal of Biological Chemistry 279 (35), 36363-36371, 2004 | 80 | 2004 |
| Agent based modeling of human gut microbiome interactions and perturbations T Shashkova, A Popenko, A Tyakht, K Peskov, Y Kosinsky, L Bogolubsky, ... PLoS One 11 (2), e0148386, 2016 | 54 | 2016 |
| Quantitative systems pharmacology: an exemplar model‐building workflow with applications in cardiovascular, metabolic, and oncology drug development G Helmlinger, V Sokolov, K Peskov, KM Hallow, Y Kosinsky, V Voronova, ... CPT: pharmacometrics & systems pharmacology 8 (6), 380-395, 2019 | 47 | 2019 |
| Quantitative mechanistic modeling in support of pharmacological therapeutics development in immuno-oncology K Peskov, I Azarov, L Chu, V Voronova, Y Kosinsky, G Helmlinger Frontiers in immunology 10, 450826, 2019 | 34 | 2019 |
| Complementarity of hydrophobic properties in ATP‐protein binding: A new criterion to rank docking solutions TV Pyrkov, YA Kosinsky, AS Arseniev, JP Priestle, E Jacoby, RG Efremov Proteins: Structure, Function, and Bioinformatics 66 (2), 388-398, 2007 | 34 | 2007 |
| Dose dependence of treatment-related adverse events for immune checkpoint inhibitor therapies: a model-based meta-analysis B Shulgin, Y Kosinsky, A Omelchenko, L Chu, G Mugundu, S Aksenov, ... Oncoimmunology 9 (1), 1748982, 2020 | 30 | 2020 |
| Molecular modelling of the nucleotide-binding domain of Wilson's disease protein: location of the ATP-binding site, domain dynamics and potential effects of the major disease … RG Efremov, YA Kosinsky, DE Nolde, R Tsivkovskii, AS Arseniev, ... Biochemical Journal 382 (1), 293-305, 2004 | 30 | 2004 |
| Kinetic modelling of NSAID action on COX-1: focus on in vitro/in vivo aspects and drug combinations A Goltsov, A Maryashkin, M Swat, Y Kosinsky, I Humphery-Smith, ... european journal of pharmaceutical sciences 36 (1), 122-136, 2009 | 26 | 2009 |
| Role of T cell-to-dendritic cell chemoattraction in T cell priming initiation in the lymph node: an agent-based modeling study I Azarov, K Peskov, G Helmlinger, Y Kosinsky Frontiers in immunology 10, 443009, 2019 | 17 | 2019 |
| A Generic Mechanism for Enhanced Cytokine Signaling via Cytokine-Neutralizing Antibodies B Shulgin, G Helmlinger, Y Kosinsky PloS one 11 (2), e0149154, 2016 | 15 | 2016 |
| Docking of ATP to Ca-ATPase: considering protein domain motions TV Pyrkov, YA Kosinsky, AS Arseniev, JP Priestle, E Jacoby, RG Efremov Journal of chemical information and modeling 47 (3), 1171-1181, 2007 | 11 | 2007 |
| Development of the force field parameters for phosphoimidazole and phosphohistidine YA Kosinsky, PE Volynsky, P Lagant, G Vergoten, EI Suzuki, AS Arseniev, ... Journal of computational chemistry 25 (11), 1313-1321, 2004 | 11 | 2004 |
| Evaluation of Combination Strategies for the A2AR Inhibitor AZD4635 Across Tumor Microenvironment Conditions via a Systems Pharmacology Model V Voronova, K Peskov, Y Kosinsky, G Helmlinger, L Chu, A Borodovsky, ... Frontiers in Immunology 12, 617316, 2021 | 10 | 2021 |
| Semi-Mechanistic pharmacokinetic-pharmacodynamic model of Camostat mesylate-predicted efficacy against SARS-CoV-2 in COVID-19 Y Kosinsky, K Peskov, DR Stanski, D Wetmore, J Vinetz Microbiology Spectrum 10 (2), e02167-21, 2022 | 5 | 2022 |
| Cycle network model of prostaglandin H synthase-1 A Goltsov, M Swat, K Peskov, Y Kosinsky Pharmaceuticals 13 (10), 265, 2020 | 3 | 2020 |
| Fusion peptide interaction with lipid bilayer: modeling with Monte Carlo simulation and continuum electrostatics calculation YA Kosinsky, PV Dubovskii, DE Nolde, AS Arseniev, RG Efremov Molecular Simulation 24 (4-6), 341-349, 2000 | 3 | 2000 |
| Elaborating on anti CTLA-4 mechanisms of action using an agent-based modeling approach I Azarov, G Helmlinger, Y Kosinsky, K Peskov Frontiers in Applied Mathematics and Statistics 8, 993581, 2022 | 2 | 2022 |
| Linking tumor microenvironment properties in murine syngeneic tumors with resistance to immune checkpoint inhibitors: Insights from a quantitative systems approach G Helmlinger, I Azarov, Y Kosinsky, V Voronova, L Chu, S Mosely, ... Cancer Research 79 (13_Supplement), 1082-1082, 2019 | 2 | 2019 |
| Quantitative modeling as a systematic approach for drug combination evaluation in immuno-oncology (IO) G Helmlinger, Y Kosinsky, L Chu, K Peskov, V Voronova, A Borodovsky, ... Cancer Research 78 (13_Supplement), 2098-2098, 2018 | 2 | 2018 |
