Selective protection of nuclease-sensitive sites in siRNA prolongs silencing effect AA Volkov, NS Kruglova, MI Meschaninova, AG Venyaminova, ... Oligonucleotides 19 (2), 191-202, 2009 | 106 | 2009 |
Carrier-free cellular uptake and the gene-silencing activity of the lipophilic siRNAs is strongly affected by the length of the linker between siRNA and lipophilic group NS Petrova, IV Chernikov, MI Meschaninova, IIS Dovydenko, ... Nucleic acids research 40 (5), 2330-2344, 2012 | 100 | 2012 |
Cholesterol-containing nuclease-resistant siRNA accumulates in tumors in a carrier-free mode and silences MDR1 gene IV Chernikov, DV Gladkikh, MI Meschaninova, AG Ven'yaminova, ... Molecular Therapy-Nucleic Acids 6, 209-220, 2017 | 75 | 2017 |
Small interfering RNA targeted to IGF-IR delays tumor growth and induces proinflammatory cytokines in a mouse breast cancer model T Durfort, M Tkach, MI Meschaninova, MA Rivas, PV Elizalde, ... PLoS One 7 (1), e29213, 2012 | 51 | 2012 |
Modeling of antigenomic therapy of mitochondrial diseases by mitochondrially addressed RNA targeting a pathogenic point mutation in mitochondrial DNA Y Tonin, AM Heckel, M Vysokikh, I Dovydenko, M Meschaninova, A Rötig, ... Journal of Biological Chemistry 289 (19), 13323-13334, 2014 | 50 | 2014 |
Targeting insulin-like growth factor I with 10–23 DNAzymes: 2′-O-methyl modifications in the catalytic core enhance mRNA cleavage AA Fokina, MI Meschaninova, T Durfort, AG Venyaminova, JC François Biochemistry 51 (11), 2181-2191, 2012 | 50 | 2012 |
Short double-stranded RNA with immunostimulatory activity: sequence dependence TO Kabilova, MI Meschaninova, AG Venyaminova, VP Nikolin, ... Nucleic acid therapeutics 22 (3), 196-204, 2012 | 31 | 2012 |
H-phosphonate synthesis of oligoribonucleotides containing modified bases. I. Photoactivatable derivatives of oligoribonucleotides with perfluoroarylazide groups in … MN Repkova, TM Ivanova, NI Komarova, AG Venyaminova, ... Russian Journal of Bioorganic Chemistry 25 (9), 690-701, 1999 | 31 | 1999 |
Novel convenient approach to the solid-phase synthesis of oligonucleotide conjugates MI Meschaninova, DS Novopashina, OA Semikolenova, VN Silnikov, ... Molecules 24 (23), 4266, 2019 | 27 | 2019 |
2'-O-Methyl–Modified Anti-MDR1 Fork-siRNA Duplexes Exhibiting High Nuclease Resistance and Prolonged Silencing Activity NS Petrova, MI Meschaninova, AG Venyaminova, MA Zenkova, ... Oligonucleotides 20 (6), 297-308, 2010 | 27 | 2010 |
Characterization of chemically modified oligonucleotides targeting a pathogenic mutation in human mitochondrial DNA Y Tonin, AM Heckel, I Dovydenko, M Meschaninova, C Comte, ... Biochimie 100, 192-199, 2014 | 25 | 2014 |
Oligo(2′-O-methylribonucleotides) and their derivatives: III. 5′-Mono- and 5′-bispyrenyl derivatives of oligo(2′-O-methylribonucleotides) and their 3 … DS Novopashina, OS Totskaya, SA Kholodar’, MI Meshchaninova, ... Russian Journal of Bioorganic Chemistry 34, 602-612, 2008 | 19 | 2008 |
Exploring the interactions of short RNAs with the human 40S ribosomal subunit near the mRNA entry site by EPR spectroscopy AA Malygin, OA Krumkacheva, DM Graifer, IO Timofeev, AS Ochkasova, ... Nucleic acids research 47 (22), 11850-11860, 2019 | 18 | 2019 |
Silencing activity of 2′-O-methyl modified anti-MDR1 siRNAs with mismatches in the central part of the duplexes NS Petrova, MI Meschaninova, AG Venyaminova, MA Zenkova, ... FEBS letters 585 (14), 2352-2356, 2011 | 18 | 2011 |
The mRNA codon environment at the P and E sites of human ribosomes deduced from photocrosslinking with pUUUGUU derivatives NA Demeshkina, ES Laletina, MI Meschaninova, MN Repkova, ... Molecular Biology 37, 132-139, 2003 | 18 | 2003 |
Fluorophore Labeling Affects the Cellular Accumulation and Gene Silencing Activity of Cholesterol-Modified siRNAs In Vitro IV Chernikov, DV Gladkikh, MI Meschaninova, UA Karelina, ... Nucleic acid therapeutics 29 (1), 33-43, 2019 | 11 | 2019 |
Arrangement of the sense and stop codons of the template in the A site of the human ribosome as inferred from crosslinking with oligonucleotide derivatives VA Styazhkina, MV Molotkov, NA Demeshkina, KN Bulygin, DM Graifer, ... Molecular Biology 37, 866-873, 2003 | 11 | 2003 |
Characterization of biological peculiarities of the radioprotective activity of double-stranded RNA isolated from Saccharomyces сerevisiae GS Ritter, VP Nikolin, NA Popova, AS Proskurina, PE Kisaretova, ... International Journal of Radiation Biology 96 (9), 1173-1191, 2020 | 10 | 2020 |
The surroundings of mRNA codons in the P and E sites of the human ribosome as inferred from photocrosslinking with pUUUGUUU NA Demeshkina, ES Laletina, MI Meshchaninova, MN Repkova, ... Mol. Biol. 37, 147-155, 2003 | 10 | 2003 |
Knockdown of the ribosomal protein eL29 in mammalian cells leads to significant changes in gene expression at the transcription level AV Gopanenko, AV Kolobova, MI Meschaninova, AG Venyaminova, ... Cells 9 (5), 1228, 2020 | 9 | 2020 |