Follow
david irwin
david irwin
Assistant professor, University Colorado Denver
Verified email at ucdenver.edu
Title
Cited by
Cited by
Year
Phase II trial of the histone deacetylase inhibitor pivaloyloxymethyl butyrate (Pivanex, AN-9) in advanced non-small cell lung cancer
T Reid, F Valone, W Lipera, D Irwin, W Paroly, R Natale, S Sreedharan, ...
Lung cancer 45 (3), 381-386, 2004
1802004
Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism
MA Cavasin, K Demos-Davies, TR Horn, LA Walker, DD Lemon, ...
Circulation research 110 (5), 739-748, 2012
1692012
Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension
DD Lemon, TR Horn, MA Cavasin, MY Jeong, KW Haubold, CS Long, ...
Journal of molecular and cellular cardiology 51 (1), 41-50, 2011
1212011
Upregulation of phase II enzymes through phytochemical activation of Nrf2 protects cardiomyocytes against oxidant stress
DJ Reuland, S Khademi, CJ Castle, DC Irwin, JM McCord, BF Miller, ...
Free Radical Biology and Medicine 56, 102-111, 2013
1072013
A potential role for reactive oxygen species and the HIF-1α–VEGF pathway in hypoxia-induced pulmonary vascular leak
DC Irwin, JM McCord, E Nozik-Grayck, G Beckly, B Foreman, T Sullivan, ...
Free Radical Biology and Medicine 47 (1), 55-61, 2009
962009
Neonatal lung side population cells demonstrate endothelial potential and are altered in response to hyperoxia-induced lung simplification
D Irwin, K Helm, N Campbell, M Imamura, K Fagan, J Harral, M Carr, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 293 (4 …, 2007
912007
TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma-and hypoxia-induced pulmonary hypertension
R Kumar, C Mickael, B Kassa, L Gebreab, JC Robinson, DE Koyanagi, ...
Nature communications 8 (1), 1-13, 2017
852017
Nrf2 activation: a potential strategy for the prevention of acute mountain sickness
C Lisk, J McCord, S Bose, T Sullivan, Z Loomis, E Nozik-Grayck, ...
Free Radical Biology and Medicine 63, 264-273, 2013
732013
Haptoglobin preserves vascular nitric oxide signaling during hemolysis
CA Schaer, JW Deuel, D Schildknecht, L Mahmoudi, I Garcia-Rubio, ...
American journal of respiratory and critical care medicine 193 (10), 1111-1122, 2016
692016
Direct ANP inhibition of hypoxia-induced inflammatory pathways in pulmonary microvascular and macrovascular endothelial monolayers
DC Irwin, MC Tissot van Patot, A Tucker, R Bowen
American Journal of Physiology-Lung Cellular and Molecular Physiology 288 (5 …, 2005
582005
Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension
JD West, ED Austin, C Gaskill, S Marriott, R Baskir, G Bilousova, JC Jean, ...
American Journal of Physiology-Cell Physiology 307 (5), C415-C430, 2014
572014
Free hemoglobin induction of pulmonary vascular disease: evidence for an inflammatory mechanism
PW Buehler, JH Baek, C Lisk, I Connor, T Sullivan, D Kominsky, S Majka, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 303 (4 …, 2012
542012
Hemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated …
DC Irwin, JH Baek, K Hassell, R Nuss, P Eigenberger, C Lisk, Z Loomis, ...
Free Radical Biology and Medicine 82, 50-62, 2015
532015
Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension
B Wojciak-Stothard, VB Abdul-Salam, KH Lao, H Tsang, DC Irwin, C Lisk, ...
Circulation 129 (17), 1770-1780, 2014
492014
Sympathetic inhibition attenuates hypoxia induced insulin resistance in healthy adult humans
GL Peltonen, RL Scalzo, MM Schweder, DG Larson, GJ Luckasen, D Irwin, ...
The Journal of Physiology 590 (11), 2801-2809, 2012
492012
Mice deficient in galectin-1 exhibit attenuated physiological responses to chronic hypoxia-induced pulmonary hypertension
D Case, D Irwin, C Ivester, J Harral, K Morris, M Imamura, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (1 …, 2007
492007
Selective depletion of vascular EC-SOD augments chronic hypoxic pulmonary hypertension
E Nozik-Grayck, C Woods, JM Taylor, RKP Benninger, RD Johnson, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 307 …, 2014
472014
Outdoor learning in Aotearoa New Zealand: Voices past, present, and future
M Cosgriff, M Legge, M Brown, M Boyes, R Zink, D Irwin
Journal of Adventure Education & Outdoor Learning 12 (3), 221-235, 2012
422012
The splenic syndrome in individuals with sickle cell trait
J Goodman, K Hassell, D Irwin, EH Witkowski, R Nuss
High altitude medicine & biology 15 (4), 468-471, 2014
392014
Acute hypobaric hypoxia (5486 m) induces greater pulmonary HIF-1 activation in hilltop compared to madison rats
BJ Engebretsen, D Irwin, ME Valdez, MK O'Donovan, A Tucker, ...
High Altitude Medicine & Biology 8 (4), 312-321, 2007
382007
The system can't perform the operation now. Try again later.
Articles 1–20