NAFLD preclinical models: more than a handful, less of a concern? Y Oligschlaeger, R Shiri-Sverdlov Biomedicines 8 (2), 28, 2020 | 94 | 2020 |
Inflammatory bowel disease: a stressed “gut/feeling” Y Oligschlaeger, T Yadati, T Houben, CM Condello Oliván, ... Cells 8 (7), 659, 2019 | 91 | 2019 |
Paternal lifestyle as a potential source of germline mutations transmitted to offspring JO Linschooten, N Verhofstad, K Gutzkow, AK Olsen, C Yauk, ... The FASEB Journal 27 (7), 2873, 2013 | 70 | 2013 |
The recruitment of AMP-activated protein kinase to glycogen is regulated by autophosphorylation Y Oligschlaeger, M Miglianico, D Chanda, R Scholz, RF Thali, R Tuerk, ... Journal of Biological Chemistry 290 (18), 11715-11728, 2015 | 56 | 2015 |
Cathepsin D regulates lipid metabolism in murine steatohepatitis T Houben, Y Oligschlaeger, T Hendrikx, AV Bitorina, SMA Walenbergh, ... Scientific reports 7 (1), 3494, 2017 | 52 | 2017 |
Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention SMA Walenbergh, T Houben, SS Rensen, V Bieghs, T Hendrikx, ... Scientific reports 6 (1), 38278, 2016 | 42 | 2016 |
Low profile high value target: the role of OxLDL in cancer AV Bitorina, Y Oligschlaeger, R Shiri-Sverdlov, J Theys Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 38 | 2019 |
The cellular apoptosis susceptibility CAS/CSE1L gene protects ovarian cancer cells from death by suppressing RASSF1C A Lorenzato, C Martino, N Dani, Y Oligschläger, AM Ferrero, N Biglia, ... The FASEB Journal 26 (6), 2446-2456, 2012 | 34 | 2012 |
2-Arachidonoylglycerol ameliorates inflammatory stress-induced insulin resistance in cardiomyocytes D Chanda, Y Oligschlaeger, I Geraets, Y Liu, X Zhu, J Li, M Nabben, ... Journal of Biological Chemistry 292 (17), 7105-7114, 2017 | 31 | 2017 |
Blood-derived macrophages prone to accumulate lysosomal lipids trigger oxLDL-dependent murine hepatic inflammation T Houben, Y Oligschlaeger, AV Bitorina, T Hendrikx, SMA Walenbergh, ... Scientific reports 7 (1), 12550, 2017 | 25 | 2017 |
Inhibiting extracellular cathepsin D reduces hepatic steatosis in Sprague–Dawley rats P Khurana, T Yadati, S Goyal, A Dolas, T Houben, Y Oligschlaeger, ... Biomolecules 9 (5), 171, 2019 | 22 | 2019 |
MSP is a negative regulator of inflammation and lipogenesis in ex vivo models of non-alcoholic steatohepatitis D Chanda, J Li, Y Oligschlaeger, MLJ Jeurissen, T Houben, ... Experimental & molecular medicine 48 (9), e258-e258, 2016 | 22 | 2016 |
Plasma cathepsin D activity rather than levels correlates with metabolic parameters of type 2 diabetes in male individuals L Ding, T Houben, Y Oligschlaeger, AV Bitorina, BJ Verwer, ... Frontiers in Endocrinology 11, 575070, 2020 | 21 | 2020 |
Nonalcoholic fatty liver disease L Ding, Y Oligschlaeger, R Shiri-Sverdlov, T Houben Prevention and Treatment of Atherosclerosis: Improving State-of-the-Art …, 2020 | 21 | 2020 |
Prevention of oxLDL uptake leads to decreased atherosclerosis in hematopoietic NPC1-deficient Ldlr−/− mice MLJ Jeurissen, SMA Walenbergh, T Houben, MJJ Gijbels, J Li, T Hendrikx, ... Atherosclerosis 255, 59-65, 2016 | 20 | 2016 |
Macrophage stimulating protein enhances hepatic inflammation in a NASH model J Li, D Chanda, PJ van Gorp, MLJ Jeurissen, T Houben, ... PLoS One 11 (9), e0163843, 2016 | 18 | 2016 |
Plasma cathepsin D activity is negatively associated with hepatic insulin sensitivity in overweight and obese humans L Ding, GH Goossens, Y Oligschlaeger, T Houben, EE Blaak, ... Diabetologia 63, 374-384, 2020 | 17 | 2020 |
Inhibition of extracellular cathepsin D reduces hepatic lipid accumulation and leads to mild changes in inflammationin NASH mice T Yadati, T Houben, A Bitorina, Y Oligschlaeger, MJ Gijbels, R Mohren, ... Frontiers in immunology 12, 675535, 2021 | 13 | 2021 |
Pneumococcal immunization reduces neurological and hepatic symptoms in a mouse model for Niemann-Pick type C1 disease T Houben, I Magro dos Reis, Y Oligschlaeger, H Steinbusch, MJJ Gijbels, ... Frontiers in immunology 9, 3089, 2019 | 12 | 2019 |
Sex‐opposed inflammatory effects of 27‐hydroxycholesterol are mediated via differences in estrogen signaling T Houben, AV Bitorina, Y Oligschlaeger, MLJ Jeurissen, S Rensen, ... The Journal of Pathology 251 (4), 429-439, 2020 | 11 | 2020 |