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Henk van Ooijen
Henk van Ooijen
Senior scientist, Philips Research
Verified email at philips.com
Title
Cited by
Cited by
Year
Selection of personalized patient therapy through the use of knowledge-based computational models that identify tumor-driving signal transduction pathways
W Verhaegh, H van Ooijen, MA Inda, P Hatzis, R Versteeg, M Smid, ...
Cancer research 74 (11), 2936-2945, 2014
1092014
Assessment of functional phosphatidylinositol 3-kinase pathway activity in cancer tissue using forkhead box-O target gene expression in a knowledge-based computational model
H Van Ooijen, M Hornsveld, C Dam-de Veen, R Velter, M Dou, ...
The American journal of pathology 188 (9), 1956-1972, 2018
562018
Enabling precision medicine by unravelling disease pathophysiology: quantifying signal transduction pathway activity across cell and tissue types
A Van De Stolpe, L Holtzer, H van Ooijen, MA Inda, W Verhaegh
Scientific reports 9 (1), 1603, 2019
522019
ER and PI3K pathway activity in primary ER positive breast cancer is associated with progression-free survival of metastatic patients under first-line tamoxifen
A M. Sieuwerts, M A. Inda, M Smid, H van Ooijen, A van de Stolpe, ...
Cancers 12 (4), 802, 2020
222020
A molecular test for quantifying functional Notch signaling pathway activity in human cancer
K Canté-Barrett, L Holtzer, H van Ooijen, R Hagelaar, V Cordo’, ...
Cancers 12 (11), 3142, 2020
142020
Abstract P5-11-06: does hormone expression by IHC predict ER pathway activity? An analysis in a metastatic breast cancer patient cohort
SR Yang, A Van De Stolpe, A Van Brussel, H Van Ooijen, A Galimzianova, ...
Cancer Research 79 (4_Supplement), P5-11-06-P5-11-06, 2019
42019
Method of visualizing a bridge therapy process
HJ Van Ooijen, R Van Den Ham, B Bakker
US Patent 9,788,798, 2017
32017
Prognosis within different breast cancer subtypes using functional activity of signaling pathways
H Van Ooijen, MA Inda, R Hoffmann, P van de Wiel, A van de Stolpe, ...
Cancer Research 75 (15_Supplement), 5291-5291, 2015
32015
Does Hormone Expression by IHC predict ER Pathway Activity? An Analysis in A Metastatic Breast Cancer Patient Cohort.
SR Yang, A van Brussel, A van de Stolpe, H van Ooijen, A Galimzianova, ...
medicine 134 (7), e48-72, 2010
32010
Development of a Notch pathway assay and quantification of functional Notch pathway activity in T-cell acute lymphoblastic leukemia
K Canté-Barrett, L Holtzer, H van Ooijen, R Hagelaar, V Cordo, ...
bioRxiv, 2020.07. 10.183731, 2020
22020
Signal transduction pathway activity during neoadjuvant treatment in esophageal adenocarcinomas
A Creemers, SL Meijer, M Stoffels, GKJ Hooijer, L Holtzer, H van Ooijen, ...
Annals of Oncology 29, viii211, 2018
22018
Estrogen receptor pathway activity in endometrial carcinomas and its relation to tumor grade and recurrence
LJ Van der Putten, A van Brussel, WJ van Weelden
Proceedings of the American Association for Cancer Research Annual Meeting …, 2018
22018
FOXO transcriptional activity is associated with response to chemoradiation in EAC
A Creemers, AP van der Zalm, A van de Stolpe, L Holtzer, M Stoffels, ...
Journal of Translational Medicine 20 (1), 183, 2022
12022
Abstract P5-02-08: androgen receptor pathway activity and the ratio between androgen and estrogen receptor pathway activity in breast cancer subtypes
A van de Stolpe, Y Wesseling-Rozendaal, MA de Inda, H van Ooijen, ...
Cancer Research 80 (4_Supplement), P5-02-08-P5-02-08, 2020
12020
Androgen receptor pathway activity and the ratio between androgen and estrogen receptor pathway activity in breast cancer subtypes
A van de Stolpe, Y Wesseling-Rozendaal, MA de Inda, H van Ooijen, ...
CANCER RESEARCH 80 (4), 2020
12020
A Test to Quantify NOTCH Pathway Activity in T Cell Acute Lymphoblastic Leukemia Patients
K Cante-Barrett, L Holtzer, H van Ooijen, R Hagelaar, W Verhaegh, ...
Blood 134, 4661, 2019
12019
Assessing functional Androgen Receptor (AR) pathway activity using a computational model
A Van Brussel, MA Inda, E Den Biezen, D van Strijp, J Wrobel, ...
Annals of Oncology 28, v593, 2017
12017
Effects of flow and diffusion on blood coagulation in platelet poor plasma
D Magnabosco, H van Ooijen, B Bakker, R van den Ham, L Formaggia
12013
Development of a qPCR based ER signaling pathway activity test predictive for response to endocrine therapy in ER IHC positive breast cancer patients
A Pierik, M Akse, H van Zon, A van Brussel, MA Inda, ...
European Journal of Cancer 138, S88-S89, 2020
2020
Development of quantitative multi-platform tests for easy readout of AR, ER, PI3K and MAPK pathway activity to unravel pathophysiology across cancer and tissue types
M Akse, H van Ooijen, A Pierik, S van den Bosch, H van Zon, L Holtzer, ...
Cancer Research 80 (16_Supplement), 4261-4261, 2020
2020
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