| Opioid analgesia and opioid-induced adverse effects: a review AK Paul, CM Smith, M Rahmatullah, V Nissapatorn, P Wilairatana, ... Pharmaceuticals 14 (11), 1091, 2021 | 137 | 2021 |
| Bone reinnervation after fracture: a study in the rat J Li, T Ahmad, M Spetea, M Ahmed, A Kreicbergs Journal of Bone and Mineral Research 16 (8), 1505-1510, 2001 | 134 | 2001 |
| In vivo brain GPCR signaling elucidated by phosphoproteomics JJ Liu, K Sharma, L Zangrandi, C Chen, SJ Humphrey, YT Chiu, M Spetea, ... Science 360 (6395), eaao4927, 2018 | 110 | 2018 |
| Peripheral versus central antinociceptive actions of 6-amino acid-substituted derivatives of 14-O-methyloxymorphone in acute and inflammatory pain in the rat S Fürst, P Riba, T Friedmann, J Tímar, M Al-Khrasani, I Obara, W Makuch, ... Journal of Pharmacology and Experimental Therapeutics 312 (2), 609-618, 2005 | 83 | 2005 |
| μ Opioid receptor: novel antagonists and structural modeling T Kaserer, A Lantero, H Schmidhammer, M Spetea, D Schuster Scientific reports 6 (1), 21548, 2016 | 81 | 2016 |
| Local peripheral antinociceptive effects of 14-O-methyloxymorphone derivatives in inflammatory and neuropathic pain in the rat I Obara, W Makuch, M Spetea, J Schütz, H Schmidhammer, R Przewlocki, ... European journal of pharmacology 558 (1-3), 60-67, 2007 | 74 | 2007 |
| Selective κ receptor partial agonist HS666 produces potent antinociception without inducing aversion after icv administration in mice M Spetea, SO Eans, ML Ganno, A Lantero, M Mairegger, L Toll, ... British Journal of Pharmacology 174 (15), 2444-2456, 2017 | 73 | 2017 |
| The μ opioid receptor and ligands acting at the μ opioid receptor, as therapeutics and potential therapeutics M Spetea, M Faheem Asim, G Wolber, H Schmidhammer Current Pharmaceutical Design 19 (42), 7415-7434, 2013 | 70 | 2013 |
| Modulation of basal and stress‐induced amygdaloid substance P release by the potent and selective NK1 receptor antagonist L‐822429 N Singewald, GG Chicchi, CC Thurner, KL Tsao, M Spetea, ... Journal of neurochemistry 106 (6), 2476-2488, 2008 | 67 | 2008 |
| Specific activation of the μ opioid receptor (MOR) by endomorphin 1 and endomorphin 2 K Monory, MC Bourin, M Spetea, C Tömböly, G Tóth, HW Matthes, ... European Journal of Neuroscience 12 (2), 577-584, 2000 | 67 | 2000 |
| In VitroBinding and Signaling Profile of the Novel μ Opioid Receptor Agonist Endomorphin 2 in Rat Brain Membranes M Spetea, K Monory, C Tömböly, G Tóth, E Tzavara, S Benyhe, ... Biochemical and biophysical research communications 250 (3), 720-725, 1998 | 62 | 1998 |
| Synthesis and biological evaluation of 14-alkoxymorphinans. 18. N-Substituted 14-phenylpropyloxymorphinan-6-ones with unanticipated agonist properties: Extending the scope of … E Greiner, M Spetea, R Krassnig, F Schüllner, M Aceto, LS Harris, ... Journal of medicinal chemistry 46 (9), 1758-1763, 2003 | 60 | 2003 |
| Alteration in endogenous opioid systems due to chronic inflammatory pain conditions M Spetea, G Rydelius, I Nylander, M Ahmed, I Bileviciute-Ljungar, ... European journal of pharmacology 435 (2-3), 245-252, 2002 | 57 | 2002 |
| Morphinans and isoquinolines: acetylcholinesterase inhibition, pharmacophore modeling, and interaction with opioid receptors D Schuster, M Spetea, M Music, S Rief, M Fink, J Kirchmair, J Schütz, ... Bioorganic & medicinal chemistry 18 (14), 5071-5080, 2010 | 54 | 2010 |
| Morphinan derivatives the quaternary ammonium salts thereof substituted in position 14, method for production and use thereof H Schmidhammer, M Spetea, J Schutz, E Greiner, F Schullner, B Sailer, ... US Patent App. 10/519,388, 2005 | 53 | 2005 |
| Discovery and pharmacological evaluation of a diphenethylamine derivative (HS665), a highly potent and selective κ opioid receptor agonist M Spetea, IP Berzetei-Gurske, E Guerrieri, H Schmidhammer Journal of medicinal chemistry 55 (22), 10302-10306, 2012 | 51 | 2012 |
| Anti-inflammatory effects of contralateral administration of the κ-opioid agonist U-50,488 H in rats with unilaterally induced adjuvant arthritis I Bileviciute-Ljungar, T Saxne, M Spetea Rheumatology 45 (3), 295-302, 2006 | 48 | 2006 |
| DAMGO and 6β-glycine substituted 14-O-methyloxymorphone but not morphine show peripheral, preemptive antinociception after systemic administration in a mouse visceral pain … M Al-Khrasani, M Spetea, T Friedmann, P Riba, K Király, ... Brain research bulletin 74 (5), 369-375, 2007 | 46 | 2007 |
| Peripherally mediated antinociception of the μ-opioid receptor agonist 2-[(4, 5α-epoxy-3-hydroxy-14β-methoxy-17-methylmorphinan-6β-yl) amino] acetic acid (HS-731) after … I Bileviciute-Ljungar, M Spetea, Y Guo, J Schütz, P Windisch, ... Journal of Pharmacology and Experimental Therapeutics 317 (1), 220-227, 2006 | 44 | 2006 |
| An opioid system in connective tissue: a study of achilles tendon in the rat PW Ackermann, M Spetea, I Nylander, K Ploj, M Ahmed, A Kreicbergs Journal of Histochemistry & Cytochemistry 49 (11), 1387-1395, 2001 | 44 | 2001 |
