Light-triggered, self-immolative nucleic acid-drug nanostructures X Tan, BB Li, X Lu, F Jia, C Santori, P Menon, H Li, B Zhang, JJ Zhao, ... Journal of the American Chemical Society 137 (19), 6112-6115, 2015 | 201 | 2015 |
Blurring the role of oligonucleotides: spherical nucleic acids as a drug delivery vehicle X Tan, X Lu, F Jia, X Liu, Y Sun, JK Logan, K Zhang Journal of the American Chemical Society 138 (34), 10834-10837, 2016 | 154 | 2016 |
Biofilm‐inspired encapsulation of probiotics for the treatment of complex infections Z Li, AM Behrens, N Ginat, SY Tzeng, X Lu, S Sivan, R Langer, ... Advanced Materials 30 (51), 1803925, 2018 | 147 | 2018 |
Engineered PLGA microparticles for long-term, pulsatile release of STING agonist for cancer immunotherapy X Lu, L Miao, W Gao, Z Chen, KJ McHugh, Y Sun, Z Tochka, S Tomasic, ... Science translational medicine 12 (556), eaaz6606, 2020 | 134 | 2020 |
Molecular spherical nucleic acids H Li, B Zhang, X Lu, X Tan, F Jia, Y Xiao, Z Cheng, Y Li, DO Silva, ... Proceedings of the National Academy of Sciences 115 (17), 4340-4344, 2018 | 114 | 2018 |
Providing oligonucleotides with steric selectivity by brush-polymer-assisted compaction X Lu, TH Tran, F Jia, X Tan, S Davis, S Krishnan, MM Amiji, K Zhang Journal of the American Chemical Society 137 (39), 12466-12469, 2015 | 95 | 2015 |
Polycondensation of polymer brushes via DNA hybridization X Lu, E Watts, F Jia, X Tan, K Zhang Journal of the American Chemical Society 136 (29), 10214-10217, 2014 | 62 | 2014 |
Bottlebrush-architectured poly (ethylene glycol) as an efficient vector for RNA interference in vivo D Wang, et al., X Lu*, K Zhang* Science advances 5 (2), eaav9322, 2019 | 60 | 2019 |
Effective antisense gene regulation via noncationic, polyethylene glycol brushes X Lu, F Jia, X Tan, D Wang, X Cao, J Zheng, K Zhang Journal of the American Chemical Society 138 (29), 9097-9100, 2016 | 55 | 2016 |
Modeling, design, and machine learning-based framework for optimal injectability of microparticle-based drug formulations M Sarmadi, AM Behrens, KJ McHugh, HTM Contreras, ZL Tochka, X Lu, ... Science advances 6 (28), eabb6594, 2020 | 50 | 2020 |
PEGylation of therapeutic oligonucletides: From linear to highly branched PEG architectures X Lu, K Zhang Nano research 11, 5519-5534, 2018 | 50 | 2018 |
Effect of PEG architecture on the hybridization thermodynamics and protein accessibility of PEGylated oligonucleotides F Jia, X Lu, X Tan, D Wang, X Cao, K Zhang Angewandte Chemie 129 (5), 1259-1263, 2017 | 50 | 2017 |
Depth-profiling the nuclease stability and the gene silencing efficacy of brush-architectured poly (ethylene glycol)–DNA conjugates F Jia, X Lu, D Wang, X Cao, X Tan, H Lu, K Zhang Journal of the American Chemical Society 139 (31), 10605-10608, 2017 | 47 | 2017 |
Two‐Pronged Intracellular Co‐Delivery of Antigen and Adjuvant for Synergistic Cancer Immunotherapy J Meng, P Zhang, Q Chen, Z Wang, Y Gu, J Ma, W Li, C Yang, Y Qiao, ... Advanced Materials 34 (21), 2202168, 2022 | 45 | 2022 |
Facile synthesis of nucleic acid–polymer amphiphiles and their self-assembly F Jia, X Lu, X Tan, K Zhang Chemical communications 51 (37), 7843-7846, 2015 | 34 | 2015 |
Polymeric PD-L1 blockade nanoparticles for cancer photothermal-immunotherapy Y Yu, J Li, B Song, Z Ma, Y Zhang, H Sun, X Wei, Y Bai, X Lu, P Zhang, ... Biomaterials 280, 121312, 2022 | 32 | 2022 |
Precision tuning of DNA-and poly (ethylene glycol)-based nanoparticles via coassembly for effective antisense gene regulation D Wang, X Lu, F Jia, X Tan, X Sun, X Cao, F Wai, C Zhang, K Zhang Chemistry of materials: a publication of the American Chemical Society 29 …, 2017 | 31 | 2017 |
Porphyrin-assisted docking of a thermophage portal protein into lipid bilayers: nanopore engineering and characterization B Cressiot, SJ Greive, W Si, TC Pascoa, M Mojtabavi, M Chechik, ... ACS nano 11 (12), 11931-11945, 2017 | 28 | 2017 |
Spherical nucleic acids for topical treatment of hyperpigmentation Y Fang, X Lu, D Wang, J Cai, Y Wang, P Chen, M Ren, H Lu, J Union, ... Journal of the American Chemical Society 143 (3), 1296-1300, 2021 | 26 | 2021 |
Modulating the Cellular Immune Response of Oligonucleotides by Brush Polymer‐Assisted Compaction X Cao#, X Lu#, D Wang, F Jia, X Tan, M Corley, X Chen, K Zhang Small 13 (43), 1701432, 2017 | 26 | 2017 |