Fast, sensitive and accurate integration of single-cell data with Harmony I Korsunsky, N Millard, J Fan, K Slowikowski, F Zhang, K Wei, ... Nature methods 16 (12), 1289-1296, 2019 | 5565 | 2019 |
Distinct fibroblast subsets drive inflammation and damage in arthritis AP Croft, J Campos, K Jansen, JD Turner, J Marshall, M Attar, L Savary, ... Nature 570 (7760), 246-251, 2019 | 785 | 2019 |
Notch signalling drives synovial fibroblast identity and arthritis pathology K Wei, I Korsunsky, JL Marshall, A Gao, GFM Watts, T Major, AP Croft, ... Nature 582 (7811), 259-264, 2020 | 391 | 2020 |
BioNetGen 2.2: advances in rule-based modeling LA Harris, JS Hogg, JJ Tapia, JAP Sekar, S Gupta, I Korsunsky, A Arora, ... Bioinformatics 32 (21), 3366-3368, 2016 | 253 | 2016 |
IL-1-driven stromal–neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies M Friedrich, M Pohin, MA Jackson, I Korsunsky, SJ Bullers, ... Nature Medicine 27 (11), 1970-1981, 2021 | 201 | 2021 |
Efficient and precise single-cell reference atlas mapping with Symphony JB Kang, A Nathan, K Weinand, F Zhang, N Millard, L Rumker, DB Moody, ... Nature communications 12 (1), 5890, 2021 | 168 | 2021 |
Mixed-effects association of single cells identifies an expanded effector CD4+ T cell subset in rheumatoid arthritis CY Fonseka, DA Rao, NC Teslovich, I Korsunsky, SK Hannes, ... Science translational medicine 10 (463), eaaq0305, 2018 | 165 | 2018 |
IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation F Zhang, JR Mears, L Shakib, JI Beynor, S Shanaj, I Korsunsky, A Nathan, ... Genome Medicine 13, 1-17, 2021 | 163 | 2021 |
Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions M Gutierrez-Arcelus, N Teslovich, AR Mola, RB Polidoro, A Nathan, H Kim, ... Nature communications 10 (1), 687, 2019 | 163 | 2019 |
Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases I Korsunsky, K Wei, M Pohin, EY Kim, F Barone, T Major, E Taylor, ... Med 3 (7), 481-518. e14, 2022 | 156 | 2022 |
CAPRI: efficient inference of cancer progression models from cross-sectional data D Ramazzotti, G Caravagna, L Olde Loohuis, A Graudenzi, I Korsunsky, ... Bioinformatics 31 (18), 3016-3026, 2015 | 105 | 2015 |
Presto scales Wilcoxon and auROC analyses to millions of observations I Korsunsky, A Nathan, N Millard, S Raychaudhuri BioRxiv, 653253, 2019 | 97 | 2019 |
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Co-varying neighborhood analysis identifies cell populations associated with phenotypes of interest from single-cell transcriptomics YA Reshef, L Rumker, JB Kang, A Nathan, I Korsunsky, S Asgari, ... Nature biotechnology 40 (3), 355-363, 2022 | 53 | 2022 |
Persons with chronic spinal cord injury have decreased natural killer cell and increased toll-like receptor/inflammatory gene expression P Herman, A Stein, K Gibbs, I Korsunsky, P Gregersen, O Bloom Journal of neurotrauma 35 (15), 1819-1829, 2018 | 50 | 2018 |
Human lung cancer harbors spatially organized stem-immunity hubs associated with response to immunotherapy JH Chen, LT Nieman, M Spurrell, V Jorgji, L Elmelech, P Richieri, KH Xu, ... Nature Immunology 25 (4), 644-658, 2024 | 42 | 2024 |
IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 and other diseases with tissue inflammation F Zhang, JR Mears, L Shakib, JI Beynor, S Shanaj, I Korsunsky, A Nathan, ... BioRxiv, 2020 | 40 | 2020 |
Novel method for high-throughput full-length IGHV-DJ sequencing of the immune repertoire from bulk B-cells with single-cell resolution S Vergani, I Korsunsky, AN Mazzarello, G Ferrer, N Chiorazzi, D Bagnara Frontiers in immunology 8, 1157, 2017 | 39 | 2017 |
Molecular signatures in systemic lupus erythematosus: distinction between disease flare and infection M Mackay, M Oswald, J Sanchez-Guerrero, J Lichauco, C Aranow, ... Lupus science & medicine 3 (1), e000159, 2016 | 37 | 2016 |
Cellular deconstruction of inflamed synovium defines diverse inflammatory phenotypes in rheumatoid arthritis F Zhang, AH Jonsson, A Nathan, K Wei, N Millard, Q Xiao, ... BioRxiv, 2022.02. 25.481990, 2022 | 36 | 2022 |