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Nicholas Denko
Nicholas Denko
professor of radiation oncology ohio state uiversity
Подтвержден адрес электронной почты в домене osumc.edu
Название
Процитировано
Процитировано
Год
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
I Papandreou, RA Cairns, L Fontana, AL Lim, NC Denko
Cell metabolism 3 (3), 187-197, 2006
25462006
Hypoxia, HIF1 and glucose metabolism in the solid tumour
NC Denko
Nature Reviews Cancer 8 (9), 705-713, 2008
19212008
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth
L Romero-Ramirez, H Cao, D Nelson, E Hammond, AH Lee, H Yoshida, ...
Cancer research 64 (17), 5943-5947, 2004
6832004
FoxO3 regulates neural stem cell homeostasis
VM Renault, VA Rafalski, AA Morgan, DAM Salih, JO Brett, AE Webb, ...
Cell stem cell 5 (5), 527-539, 2009
6232009
Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma
I Papandreou, NC Denko, M Olson, H Van Melckebeke, S Lust, A Tam, ...
Blood, The Journal of the American Society of Hematology 117 (4), 1311-1314, 2011
5262011
Candidate genes for the hypoxic tumor phenotype
AC Koong, NC Denko, KM Hudson, C Schindler, L Swiersz, C Koch, ...
Cancer research 60 (4), 883-887, 2000
4452000
Overcoming physiologic barriers to cancer treatment by molecularly targeting the tumor microenvironment
R Cairns, I Papandreou, N Denko
Molecular Cancer Research 4 (2), 61-70, 2006
4292006
Hypoxia links ATR and p53 through replication arrest
EM Hammond, NC Denko, MJ Dorie, RT Abraham, AJ Giaccia
Molecular and cellular biology 22 (6), 1834-1843, 2002
4032002
Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L
I Papandreou, AL Lim, K Laderoute, NC Denko
Cell Death & Differentiation 15 (10), 1572-1581, 2008
4002008
Investigating hypoxic tumor physiology through gene expression patterns
NC Denko, LA Fontana, KM Hudson, PD Sutphin, S Raychaudhuri, ...
Oncogene 22 (37), 5907-5914, 2003
3982003
Hypoxic regulation of glutamine metabolism through HIF1 and SIAH2 supports lipid synthesis that is necessary for tumor growth
RC Sun, NC Denko
Cell metabolism 19 (2), 285-292, 2014
3502014
Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1α
DA Chan, PD Sutphin, NC Denko, AJ Giaccia
Journal of biological chemistry 277 (42), 40112-40117, 2002
3472002
Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1α
DA Chan, PD Sutphin, NC Denko, AJ Giaccia
Journal of biological chemistry 277 (42), 40112-40117, 2002
3472002
Hypoxia induces a novel signature of chromatin modifications and global repression of transcription
AB Johnson, N Denko, MC Barton
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 640 (1 …, 2008
3022008
Hypoxic gene expression and metastasis
QT Le, NC Denko, AJ Giaccia
Cancer and Metastasis Reviews 23, 293-310, 2004
2942004
The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle.
NC Denko, AJ Giaccia, JR Stringer, PJ Stambrook
Proceedings of the National Academy of Sciences 91 (11), 5124-5128, 1994
2741994
Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect
Y Chen, R Cairns, I Papandreou, A Koong, NC Denko
PloS one 4 (9), e7033, 2009
2292009
Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect
Y Chen, R Cairns, I Papandreou, A Koong, NC Denko
PloS one 4 (9), e7033, 2009
2292009
Hypoxic Activation of Nuclear Factor-κB Is Mediated by a Ras and Raf Signaling Pathway and Does Not Involve MAP Kinase (ERK1 or ERK2)
AC Koong, EY Chen, NF Mivechi, NC Denko, P Stambrook, AJ Giaccia
Cancer research 54 (20), 5273-5279, 1994
2101994
Epigenetic regulation of gene expression in cervical cancer cells by the tumor microenvironment
N Denko, C Schindler, A Koong, K Laderoute, C Green, A Giaccia
Clinical Cancer Research 6 (2), 480-487, 2000
2092000
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Статьи 1–20