| Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding EC Twomey, Z Ji, TE Wales, NO Bodnar, SB Ficarro, JA Marto, JR Engen, ... Science 365 (6452), eaax1033, 2019 | 260 | 2019 |
| Channel opening and gating mechanism in AMPA-subtype glutamate receptors EC Twomey, MV Yelshanskaya, RA Grassucci, J Frank, AI Sobolevsky Nature 549 (7670), 60-65, 2017 | 222 | 2017 |
| Opening of the human epithelial calcium channel TRPV6 LL McGoldrick, AK Singh, K Saotome, MV Yelshanskaya, EC Twomey, ... Nature 553 (7687), 233-237, 2018 | 188 | 2018 |
| Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy EC Twomey, MV Yelshanskaya, RA Grassucci, J Frank, AI Sobolevsky Science 353 (6924), 83-86, 2016 | 132 | 2016 |
| Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes EC Twomey, MV Yelshanskaya, J Grassucci, R.A., Frank, AI Sobolevsky Neuron 94 (3), 569-580, 2017 | 110 | 2017 |
| Structural mechanisms of gating in ionotropic glutamate receptors EC Twomey, AI Sobolevsky Biochemistry 57 (3), 267–276, 2018 | 108 | 2018 |
| Mechanisms of channel block in calcium-permeable AMPA receptors EC Twomey, MV Yelshanskaya, AA Vassilevski, AI Sobolevsky Neuron 99 (5), 956-968. e4, 2018 | 103 | 2018 |
| Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6 AK Singh, LL McGoldrick, EC Twomey, AI Sobolevsky Science Advances 4 (8), eaau6088, 2018 | 92 | 2018 |
| Structural and functional insights into transmembrane AMPA receptor regulatory protein complexes EC Twomey, MV Yelshanskaya, AI Sobolevsky Journal of General Physiology 151 (12), 1347-1356, 2019 | 30 | 2019 |
| High-definition NMR structure of PED/PEA-15 death effector domain reveals details of key polar side chain interactions EC Twomey, Y Wei Biochemical and Biophysical Research Communications 424 (1), 141-146, 2012 | 14 | 2012 |
| Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Science 365, eaax1033 EC Twomey, Z Ji, TE Wales, NO Bodnar, SB Ficarro, JA Marto, JR Engen, ... | 12 | 2019 |
| Profound conformational changes of PED/PEA-15 in ERK2 complex revealed by NMR backbone dynamics EC Twomey, DF Cordasco, Y Wei Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1824 (12), 1382-1393, 2012 | 10 | 2012 |
| Substantial conformational change mediated by charge-triad residues of the death effector domain in protein-protein interactions EC Twomey, DF Cordasco, SD Kozuch, Y Wei PLoS One 8 (12), e83421, 2013 | 7 | 2013 |
| NMR spectroscopic characterization of death domain superfamily proteins: Structures, dynamics and interactions Y Wei, EC Twomey Nuclear Magnetic Resonance (NMR): Theory, Applications and Technology, 83-110, 2014 | 2 | 2014 |
| Structure of Transmembrane AMPA Receptor Regulatory Protein Subunit γ2 WD Hale, AM Romero, RL Huganir, EC Twomey Biorxiv, 2023.11. 28.569079, 2023 | 1 | 2023 |
| Allosteric Competition and Inhibition in AMPA Receptors WD Hale, AM Romero, CU Gonzalez, V Jayaraman, AY Lau, RL Huganir, ... Biorxiv, 2023.11. 28.569057, 2023 | 1 | 2023 |
| Mechanism of glutamate receptor block by acylpolyamines EC Twomey, MV Yelshanskaya, AI Sobolevsky, AA Vassilevski Toxicon 159, S7, 2019 | 1 | 2019 |
| How we sense glutamate: Allosteric regulation of AMPA receptors EC Twomey Biophysical Journal 123 (3), 531a, 2024 | | 2024 |
| Inhibition of AMPA-subtype ionotropic glutamate receptors WD Hale, AM Romero, L Dillard, AY Lau, R Huganir, EC Twomey Biophysical Journal 123 (3), 161a, 2024 | | 2024 |
| C-SPAM: an open-source time-resolved specimen vitrification device with light-activated molecules A Montaño Romero, C Bonin, EC Twomey IUCrJ 11 (1), 2024 | | 2024 |
Alexander SobolevskyAssociate Professor of Biochemistry and Molecular Biophysics, Columbia UniversityVerified email at cumc.columbia.edu
