| Opioid activation of toll-like receptor 4 contributes to drug reinforcement MR Hutchinson, AL Northcutt, T Hiranita, X Wang, SS Lewis, J Thomas, ... Journal of Neuroscience 32 (33), 11187-11200, 2012 | 304 | 2012 |
| DAT isn’t all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling AL Northcutt, MR Hutchinson, X Wang, MV Baratta, T Hiranita, ... Molecular psychiatry 20 (12), 1525-1537, 2015 | 208 | 2015 |
| Endocannabinoid system modulates relapse to methamphetamine seeking: possible mediation by the arachidonic acid cascade K Anggadiredja, M Nakamichi, T Hiranita, H Tanaka, Y Shoyama, ... Neuropsychopharmacology 29 (8), 1470-1478, 2004 | 143 | 2004 |
| Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain Z Freyberg, MS Sonders, JI Aguilar, T Hiranita, CS Karam, J Flores, ... Nature communications 7 (1), 10652, 2016 | 132 | 2016 |
| Investigation of the adrenergic and opioid binding affinities, metabolic stability, plasma protein binding properties, and functional effects of selected indole-based kratom … S Obeng, SH Kamble, ME Reeves, LF Restrepo, A Patel, M Behnke, ... Journal of medicinal chemistry 63 (1), 433-439, 2019 | 109 | 2019 |
| Suppression of methamphetamine-seeking behavior by nicotinic agonists T Hiranita, Y Nawata, K Sakimura, K Anggadiredja, T Yamamoto Proceedings of the National Academy of Sciences 103 (22), 8523-8527, 2006 | 109 | 2006 |
| Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self-administration in rats: comparisons with monoamine uptake inhibitors T Hiranita, PL Soto, AH Newman, JL Katz Journal of Pharmacology and Experimental Therapeutics 329 (2), 677-686, 2009 | 103 | 2009 |
| Sigma receptor agonists: receptor binding and effects on mesolimbic dopamine neurotransmission assessed by microdialysis L Garcés-Ramírez, JL Green, T Hiranita, TA Kopajtic, M Mereu, ... Biological psychiatry 69 (3), 208-217, 2011 | 97 | 2011 |
| Reinforcing effects of σ-receptor agonists in rats trained to self-administer cocaine T Hiranita, PL Soto, G Tanda, JL Katz Journal of Pharmacology and Experimental Therapeutics 332 (2), 515-524, 2010 | 90 | 2010 |
| The sigma-1 receptor modulates dopamine transporter conformation and cocaine binding and may thereby potentiate cocaine self-administration in rats WC Hong, H Yano, T Hiranita, FT Chin, CR McCurdy, TP Su, SG Amara, ... Journal of Biological Chemistry 292 (27), 11250-11261, 2017 | 87 | 2017 |
| Naltrexone attenuates cue-but not drug-induced methamphetamine seeking: a possible mechanism for the dissociation of primary and secondary reward K Anggadiredja, K Sakimura, T Hiranita, T Yamamoto Brain research 1021 (2), 272-276, 2004 | 79 | 2004 |
| Mice lacking the schizophrenia-associated protein FEZ1 manifest hyperactivity and enhanced responsiveness to psychostimulants N Sakae, N Yamasaki, K Kitaichi, T Fukuda, M Yamada, H Yoshikawa, ... Human molecular genetics 17 (20), 3191-3203, 2008 | 71 | 2008 |
| Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and σ receptors T Hiranita, PL Soto, SJ Kohut, T Kopajtic, J Cao, AH Newman, G Tanda, ... Journal of Pharmacology and Experimental Therapeutics 339 (2), 662-677, 2011 | 70 | 2011 |
| A role for sigma receptors in stimulant self administration and addiction JL Katz, TP Su, T Hiranita, T Hayashi, G Tanda, T Kopajtic, SY Tsai Pharmaceuticals 4 (6), 880-914, 2011 | 69 | 2011 |
| Pharmacological comparison of mitragynine and 7-hydroxymitragynine: in vitro affinity and efficacy for μ-opioid receptor and opioid-like behavioral effects in rats S Obeng, JL Wilkerson, F León, ME Reeves, LF Restrepo, ... Journal of Pharmacology and Experimental Therapeutics 376 (3), 410-427, 2021 | 64 | 2021 |
| A role for sigma receptors in stimulant self-administration and addiction JL Katz, T Hiranita, WC Hong, MO Job, CR McCurdy Sigma Proteins: Evolution of the Concept of Sigma Receptors, 177-218, 2017 | 62 | 2017 |
| Miscibility behavior of dipalmitoylphosphatidylcholine with a single-chain partially fluorinated amphiphile in Langmuir monolayers T Hiranita, S Nakamura, M Kawachi, HM Courrier, TF Vandamme, ... Journal of colloid and interface science 265 (1), 83-92, 2003 | 62 | 2003 |
| Preclinical efficacy of N-substituted benztropine analogs as antagonists of methamphetamine self-administration in rats T Hiranita, SJ Kohut, PL Soto, G Tanda, TA Kopajtic, JL Katz Journal of Pharmacology and Experimental Therapeutics 348 (1), 174-191, 2014 | 55 | 2014 |
| Lack of specific involvement of (+)-naloxone and (+)-naltrexone on the reinforcing and neurochemical effects of cocaine and opioids G Tanda, M Mereu, T Hiranita, JC Quarterman, M Coggiano, JL Katz Neuropsychopharmacology 41 (11), 2772-2781, 2016 | 54 | 2016 |
| Novel approaches, drug candidates, and targets in pain drug discovery S Obeng, T Hiranita, F León, LR McMahon, CR McCurdy Journal of medicinal chemistry 64 (10), 6523-6548, 2021 | 52 | 2021 |
