| One in a Million: Flow Cytometric Sorting of Single Cell-Lysate Assays in Monodisperse Picolitre Double Emulsion Droplets for Directed Evolution A Zinchenko, SRA Devenish, B Kintses, PY Colin, M Fischlechner, ... Analytical chemistry 86 (5), 2526-2533, 2014 | 233 | 2014 |
| Microfluidic droplets: new integrated workflows for biological experiments B Kintses, LD van Vliet, SRA Devenish, F Hollfelder Current opinion in chemical biology 14 (5), 548-555, 2010 | 215 | 2010 |
| Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies S Linse, T Scheidt, K Bernfur, M Vendruscolo, CM Dobson, SIA Cohen, ... Nature Structural & Molecular Biology 27 (12), 1125-1133, 2020 | 134 | 2020 |
| A Fully Unsupervised Compartment-on-Demand Platform for Precise Nanoliter Assays of Time-Dependent Steady-State Enzyme Kinetics and Inhibition F Gielen, L van Vliet, BT Koprowski, SRA Devenish, M Fischlechner, ... Analytical chemistry 85 (9), 4761-4769, 2013 | 104 | 2013 |
| Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis G Kefala, GL Evans, MDW Griffin, SRA Devenish, FG Pearce, MA Perugini, ... Biochemical Journal 411 (2), 351-360, 2008 | 86 | 2008 |
| Inhibiting dihydrodipicolinate synthase across species: Towards specificity for pathogens? V Mitsakos, RCJ Dobson, FG Pearce, SR Devenish, GL Evans, ... Bioorganic & medicinal chemistry letters 18 (2), 842-844, 2008 | 58 | 2008 |
| Accessing unexplored regions of sequence space in directed enzyme evolution via insertion/deletion mutagenesis S Emond, M Petek, EJ Kay, B Heames, SRA Devenish, N Tokuriki, ... Nature communications 11 (1), 3469, 2020 | 57 | 2020 |
| Role of arginine 138 in the catalysis and regulation of Escherichia coli dihydrodipicolinate synthase RCJ Dobson, SRA Devenish, LA Turner, VR Clifford, FG Pearce, ... Biochemistry 44 (39), 13007-13013, 2005 | 56 | 2005 |
| A single mutation in the core domain of the lac repressor reduces leakiness P Gatti-Lafranconi, WP Dijkman, SRA Devenish, F Hollfelder Microb. Cell Fact 12 (67.10), 1186, 2013 | 50 | 2013 |
| On-chip label-free protein analysis with downstream electrodes for direct removal of electrolysis products KL Saar, Y Zhang, T Müller, CP Kumar, S Devenish, A Lynn, U Łapińska, ... Lab on a Chip 18 (1), 162-170, 2018 | 49 | 2018 |
| Dual side-reactions limit the utility of a key polymer therapeutic precursor SRA Devenish, JB Hill, JW Blunt, JC Morris, MHG Munro Tetrahedron letters 47 (17), 2875-2878, 2006 | 45 | 2006 |
| How essential is the ‘essential’active-site lysine in dihydrodipicolinate synthase? TPS da Costa, AC Muscroft-Taylor, RCJ Dobson, SRA Devenish, ... Biochimie 92 (7), 837-845, 2010 | 43 | 2010 |
| A simple method to evaluate the biochemical compatibility of oil/surfactant mixtures for experiments in microdroplets M Kaltenbach, SRA Devenish, F Hollfelder Lab on a Chip 12 (20), 4185-4192, 2012 | 41 | 2012 |
| Conserved main‐chain peptide distortions: A proposed role for Ile203 in catalysis by dihydrodipicolinate synthase RCJ Dobson, MDW Griffin, SRA Devenish, FG Pearce, CA Hutton, ... Protein Science 17 (12), 2080-2090, 2008 | 41 | 2008 |
| Cloning and characterisation of dihydrodipicolinate synthase from the pathogen Neisseria meningitidis SRA Devenish, FHA Huisman, EJ Parker, AT Hadfield, JA Gerrard Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1794 (8), 1168-1174, 2009 | 39 | 2009 |
| NMR studies uncover alternate substrates for dihydrodipicolinate synthase and suggest that dihydrodipicolinate reductase is also a dehydratase SRA Devenish, JW Blunt, JA Gerrard Journal of medicinal chemistry 53 (12), 4808-4812, 2010 | 35 | 2010 |
| Characterisation of dihydrodipicolinate synthase (DHDPS) from Bacillus anthracis LJ Domigan, SW Scally, MJ Fogg, CA Hutton, MA Perugini, RCJ Dobson, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1794 (10), 1510-1516, 2009 | 35 | 2009 |
| The role of quaternary structure in (β/α) 8-barrel proteins: evolutionary happenstance or a higher level of structure-function relationships? SRA Devenish, JA Gerrard Organic & biomolecular chemistry 7 (5), 833-839, 2009 | 33 | 2009 |
| Antibody affinity governs the inhibition of SARS-CoV-2 spike/ACE2 binding in patient serum S Fiedler, MA Piziorska, V Denninger, AS Morgunov, A Ilsley, AY Malik, ... ACS infectious diseases 7 (8), 2362-2369, 2021 | 31 | 2021 |
| The high-resolution structure of dihydrodipicolinate synthase from Escherichia coli bound to its first substrate, pyruvate SRA Devenish, JA Gerrard, GB Jameson, RCJ Dobson Acta Crystallographica Section F: Structural Biology and Crystallization …, 2008 | 30 | 2008 |
