Organoid models of human and mouse ductal pancreatic cancer SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ... Cell 160 (1), 324-338, 2015 | 2080 | 2015 |
Sambamba: fast processing of NGS alignment formats A Tarasov, AJ Vilella, E Cuppen, IJ Nijman, P Prins Bioinformatics 31 (12), 2032-2034, 2015 | 1856 | 2015 |
A living biobank of breast cancer organoids captures disease heterogeneity N Sachs, J De Ligt, O Kopper, E Gogola, G Bounova, F Weeber, ... Cell 172 (1), 373-386. e10, 2018 | 1694 | 2018 |
Tissue-specific mutation accumulation in human adult stem cells during life F Blokzijl, J De Ligt, M Jager, V Sasselli, S Roerink, N Sasaki, M Huch, ... Nature 538 (7624), 260-264, 2016 | 935 | 2016 |
Whole-genome sequence variation, population structure and demographic history of the Dutch population Nature genetics 46 (8), 818-825, 2014 | 731 | 2014 |
A systematic genome-wide analysis of zebrafish protein-coding gene function RNW Kettleborough, EM Busch-Nentwich, SA Harvey, CM Dooley, ... Nature 496 (7446), 494-497, 2013 | 727 | 2013 |
A medium-density genetic linkage map of the bovine genome W Barendse, D Vaiman, SJ Kemp, Y Sugimoto, SM Armitage, JL Williams, ... Mammalian Genome 8, 21-28, 1997 | 494 | 1997 |
Llama heavy-chain V regions consist of at least four distinct subfamilies revealing novel sequence features MM Harmsen, RC Ruuls, IJ Nijman, TA Niewold, LGJ Frenken, B de Geus Molecular immunology 37 (10), 579-590, 2000 | 294 | 2000 |
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells P Hatzis, LG van der Flier, MA van Driel, V Guryev, F Nielsen, S Denissov, ... Molecular and cellular biology, 2008 | 289 | 2008 |
Pyrosequencing-based comparative genome analysis of the nosocomial pathogen Enterococcus faecium and identification of a large transferable pathogenicity … W van Schaik, J Top, DR Riley, J Boekhorst, JEP Vrijenhoek, ... BMC genomics 11, 1-18, 2010 | 253 | 2010 |
Dominant missense mutations in ABCC9 cause Cantú syndrome M Harakalova, JJT Van Harssel, PA Terhal, S Van Lieshout, K Duran, ... Nature genetics 44 (7), 793-796, 2012 | 218 | 2012 |
Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer WP Kloosterman, M Hoogstraat, O Paling, M Tavakoli-Yaraki, I Renkens, ... Genome biology 12, 1-11, 2011 | 211 | 2011 |
Maternal and paternal lineages in cross-breeding bovine species. Has wisent a hybrid origin? ELC Verkaar, IJ Nijman, M Beeke, E Hanekamp, JA Lenstra Molecular biology and evolution 21 (7), 1165-1170, 2004 | 208 | 2004 |
Hybridization of banteng (Bos javanicus) and zebu (Bos indicus) revealed by mitochondrial DNA, satellite DNA, AFLP and microsatellites IJ Nijman, M Otsen, ELC Verkaar, C De Ruijter, E Hanekamp, JW Ochieng, ... Heredity 90 (1), 10-16, 2003 | 203 | 2003 |
Effectiveness of whole-exome sequencing and costs of the traditional diagnostic trajectory in children with intellectual disability GR Monroe, GW Frederix, S Savelberg, TI De Vries, KJ Duran, ... Genetics in Medicine 18 (9), 949-956, 2016 | 195 | 2016 |
Targeted next-generation sequencing: a novel diagnostic tool for primary immunodeficiencies IJ Nijman, JM van Montfrans, M Hoogstraat, ML Boes, L van de Corput, ... Journal of Allergy and Clinical Immunology 133 (2), 529-534. e1, 2014 | 192 | 2014 |
Loss of syntaxin 3 causes variant microvillus inclusion disease CL Wiegerinck, AR Janecke, K Schneeberger, GF Vogel, ... Gastroenterology 147 (1), 65-68. e10, 2014 | 187 | 2014 |
Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment JS Vermaat, IJ Nijman, MJ Koudijs, FL Gerritse, SJ Scherer, M Mokry, ... Clinical cancer research 18 (3), 688-699, 2012 | 179 | 2012 |
Phylogeny of bovine species based on AFLP fingerprinting JB Buntjer, M Otsen, IJ Nijman, MTR Kuiper, JA Lenstra Heredity 88 (1), 46-51, 2002 | 163 | 2002 |
Molecular characterisation of the Theileria buffeli/orientalis group MJ Gubbels, Y Hong, M van der Weide, B Qi, IJ Nijman, L Guangyuan, ... International Journal for Parasitology 30 (8), 943-952, 2000 | 163 | 2000 |