Reid J. Leonard
Reid J. Leonard
Potenza Therapeutics
Подтвержден адрес электронной почты в домене potenzatx.com
Functional role of the β subunit of high conductance calcium-activated potassium channels
OB McManus, LMH Helms, L Pallanck, B Ganetzky, R Swanson, ...
Neuron 14 (3), 645-650, 1995
Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor
RJ Leonard, CG Labarca, P Charnet, N Davidson, HA Lester
Science 242 (4885), 1578-1581, 1988
Purification, characterization, and biosynthesis of margatoxin, a component of Centruroides margaritatus venom that selectively inhibits voltage-dependent potassium channels.
M Garcia-Calvo, RJ Leonard, J Novick, SP Stevens, W Schmalhofer, ...
Journal of Biological Chemistry 268 (25), 18866-18874, 1993
High-conductance calcium-activated potassium channels; structure, pharmacology, and function
GJ Kaczorowski, HG Knaus, RJ Leonard, OB McManus, ML Garcia
Journal of bioenergetics and biomembranes 28 (3), 255-267, 1996
Selective blockers of voltage-gated K+ channels depolarize human T lymphocytes: mechanism of the antiproliferative effect of charybdotoxin.
RJ Leonard, ML Garcia, RS Slaughter, JP Reuben
Proceedings of the National Academy of Sciences 89 (21), 10094-10098, 1992
An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor
P Charnet, C Labarca, RJ Leonard, NJ Vogelaar, L Czyzyk, A Gouin, ...
Neuron 4 (1), 87-95, 1990
Acetylcholine raises excitability by inhibiting the fast transient potassium current in cultured hippocampal neurons.
Y Nakajima, S Nakajima, RJ Leonard, K Yamaguchi
Proceedings of the National Academy of Sciences 83 (9), 3022-3026, 1986
Growth hormone secretagogue receptor family members and ligands
RG Smith, R Leonard, ART Bailey, O Palyha, S Feighner, C Tan, ...
Endocrine 14 (1), 9-14, 2001
Modulation of pulsatile GH release through a novel receptor in hypothalamus and pituitary gland.
RG Smith, SS Pong, G Hickey, T Jacks, K Cheng, R Leonard, CJ Cohen, ...
Recent Progress in Hormone Research 51, 261-85; discussion 285, 1996
Synthetic charybdotoxin-iberiotoxin chimeric peptides define toxin binding sites on calcium-activated and voltage-dependent potassium channels
KM Giangiacomo, EE Sugg, M Garcia-Calvo, RJ Leonard, OB McManus, ...
Biochemistry 32 (9), 2363-2370, 1993
Adenosine: a partial agonist of the growth hormone secretagogue receptor
RG Smith, PR Griffin, Y Xu, AGA Smith, K Liu, J Calacay, SD Feighner, ...
Biochemical and biophysical research communications 276 (3), 1306-1313, 2000
Margatoxin Binds to a Homomultimer of KV1.3 Channels in Jurkat Cells. Comparison with KV1.3 Expressed in CHO Cells
LMH Helms, JP Felix, RM Bugianesi, ML Garcia, S Stevens, RJ Leonard, ...
Biochemistry 36 (12), 3737-3744, 1997
Chemical synthesis and structure-function studies of margatoxin, a potent inhibitor of voltage-dependent potassium channel in human T lymphocytes
MA Bednarek, RM Bugianesi, RJ Leonard, JP Felix
Biochemical and biophysical research communications 198 (2), 619-625, 1994
Differential development of two classes of acetylcholine receptors in Xenopus muscle in culture
RJ Leonard, S Nakajima, Y Nakajima, T Takahashi
Science 226 (4670), 55-57, 1984
Expression of Drosophila Shaker potassium channels in mammalian cells infected with recombinant vaccinia virus.
RJ Leonard, A Karschin, S Jayashree-Aiyar, N Davidson, MA Tanouye, ...
Proceedings of the National Academy of Sciences 86 (19), 7629-7633, 1989
Light modulates voltage-dependent potassium channels in Limulus ventral photoreceptors
RJ Leonard, JE Lisman
Science 212 (4500), 1273-1275, 1981
Mechanism of action of GHRP-6 and nonpeptidyl growth hormone secretagogues
RG Smith, K Cheng, SS Pong, R Leonard, CJ Cohen, JP Arena, ...
Growth hormone secretagogues, 147-163, 1996
Scorpion peptide margatoxin with immunosuppressant activity
ML Garcia, GC Koo, RJ Leonard, CCS Lin, RS Slaughter, SP Stevens, ...
US Patent 5,494,895, 1996
Reverse pharmacology of the nicotinic acetylcholine receptor. Mapping the local anesthetic binding site.
RJ Leonard, P Charnet, C Labarca, NJ Vogelaar, L Czyzyk, A Gouin, ...
Annals of the New York Academy of Sciences 625, 588-599, 1991
Stable expression of human Kv1. 3 potassium channels resets the resting membrane potential of cultured mammalian cells.
FP Defarias, SP Stevens, RJ Leonard
Receptors & channels 3 (4), 273-281, 1995
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