Flow-induced elongation of von Willebrand factor precedes tension-dependent activation H Fu, Y Jiang, D Yang, F Scheiflinger, WP Wong, TA Springer Nature communications 8 (1), 324, 2017 | 196 | 2017 |
Probing single biomolecules in solution using the anti-Brownian electrokinetic (ABEL) trap Q Wang, RH Goldsmith, Y Jiang, SD Bockenhauer, WE Moerner Accounts of chemical research 45 (11), 1955-1964, 2012 | 97 | 2012 |
Sensing cooperativity in ATP hydrolysis for single multisubunit enzymes in solution Y Jiang, NR Douglas, NR Conley, EJ Miller, J Frydman, WE Moerner Proceedings of the National Academy of Sciences 108 (41), 16962-16967, 2011 | 89 | 2011 |
Super-resolution fluorescence of huntingtin reveals growth of globular species into short fibers and coexistence of distinct aggregates WC Duim, Y Jiang, K Shen, J Frydman, WE Moerner ACS chemical biology 9 (12), 2767-2778, 2014 | 65 | 2014 |
Hardware-based anti-Brownian electrokinetic trap (ABEL trap) for single molecules: Control loop simulations and application to ATP binding stoichiometry in multi-subunit enzymes Y Jiang, Q Wang, AE Cohen, N Douglas, J Frydman, WE Moerner Optical Trapping and Optical Micromanipulation V 7038, 31-42, 2008 | 27 | 2008 |
Electrostatic steering enables flow-activated Von Willebrand factor to bind platelet glycoprotein, revealed by single-molecule stretching and imaging Y Jiang, H Fu, TA Springer, WP Wong Journal of molecular biology 431 (7), 1380-1396, 2019 | 26 | 2019 |
Conformation of von Willebrand factor in shear flow revealed with stroboscopic single-molecule imaging HT Bergal, Y Jiang, D Yang, TA Springer, WP Wong Blood, The Journal of the American Society of Hematology 140 (23), 2490-2499, 2022 | 8 | 2022 |
Single-molecule imaging of von Willebrand factor reveals tension-dependent self-association H Fu, Y Jiang, WP Wong, TA Springer Blood, The Journal of the American Society of Hematology 138 (23), 2425-2434, 2021 | 7 | 2021 |
Stretching DNA to twice the normal length with single-molecule hydrodynamic trapping Y Jiang, T Feldman, JAM Bakx, D Yang, WP Wong Lab on a Chip 20 (10), 1780-1791, 2020 | 7 | 2020 |
Shear flow has minimal role in unfolding of free von Willebrand factor H Bergal, Y Jiang, D Yang, TA Springer, WP Wong Biophysical Journal 121 (3), 283a, 2022 | | 2022 |
Stretching and Activation of Single Protein Molecules by Flow Reveals the Mechanism of von Willebrand Factor Adhesion Y Jiang, H Fu, D Yang, F Scheiflinger, TA Springer, WP Wong Biophysical Journal 114 (3), 18a, 2018 | | 2018 |
Single-Molecule Activation by Flow: Force-Induced Conformational Transitions Regulate the Ligand Binding Affinity of a Large, Polymeric Mechanosensor Protein H Fu, Y Jiang, D Yang, WP Wong, TA Springer Biophysical Journal 110 (3), 348a, 2016 | | 2016 |
Single-Molecule Imaging of Von Willebrand Factor Activation by Flow Y Jiang, H Fu, D Yang, TA Springer, WP Wong Biophysical Journal 106 (2), 194a, 2014 | | 2014 |