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Yan Jiang
Yan Jiang
Research Associate at PCMM, Children's Hospital Boston, and BCMP, Harvard Medical School
Подтвержден адрес электронной почты в домене childrens.harvard.edu
Название
Процитировано
Процитировано
Год
Flow-induced elongation of von Willebrand factor precedes tension-dependent activation
H Fu, Y Jiang, D Yang, F Scheiflinger, WP Wong, TA Springer
Nature communications 8 (1), 324, 2017
1962017
Probing single biomolecules in solution using the anti-Brownian electrokinetic (ABEL) trap
Q Wang, RH Goldsmith, Y Jiang, SD Bockenhauer, WE Moerner
Accounts of chemical research 45 (11), 1955-1964, 2012
972012
Sensing cooperativity in ATP hydrolysis for single multisubunit enzymes in solution
Y Jiang, NR Douglas, NR Conley, EJ Miller, J Frydman, WE Moerner
Proceedings of the National Academy of Sciences 108 (41), 16962-16967, 2011
892011
Super-resolution fluorescence of huntingtin reveals growth of globular species into short fibers and coexistence of distinct aggregates
WC Duim, Y Jiang, K Shen, J Frydman, WE Moerner
ACS chemical biology 9 (12), 2767-2778, 2014
652014
Hardware-based anti-Brownian electrokinetic trap (ABEL trap) for single molecules: Control loop simulations and application to ATP binding stoichiometry in multi-subunit enzymes
Y Jiang, Q Wang, AE Cohen, N Douglas, J Frydman, WE Moerner
Optical Trapping and Optical Micromanipulation V 7038, 31-42, 2008
272008
Electrostatic steering enables flow-activated Von Willebrand factor to bind platelet glycoprotein, revealed by single-molecule stretching and imaging
Y Jiang, H Fu, TA Springer, WP Wong
Journal of molecular biology 431 (7), 1380-1396, 2019
262019
Conformation of von Willebrand factor in shear flow revealed with stroboscopic single-molecule imaging
HT Bergal, Y Jiang, D Yang, TA Springer, WP Wong
Blood, The Journal of the American Society of Hematology 140 (23), 2490-2499, 2022
82022
Single-molecule imaging of von Willebrand factor reveals tension-dependent self-association
H Fu, Y Jiang, WP Wong, TA Springer
Blood, The Journal of the American Society of Hematology 138 (23), 2425-2434, 2021
72021
Stretching DNA to twice the normal length with single-molecule hydrodynamic trapping
Y Jiang, T Feldman, JAM Bakx, D Yang, WP Wong
Lab on a Chip 20 (10), 1780-1791, 2020
72020
Shear flow has minimal role in unfolding of free von Willebrand factor
H Bergal, Y Jiang, D Yang, TA Springer, WP Wong
Biophysical Journal 121 (3), 283a, 2022
2022
Stretching and Activation of Single Protein Molecules by Flow Reveals the Mechanism of von Willebrand Factor Adhesion
Y Jiang, H Fu, D Yang, F Scheiflinger, TA Springer, WP Wong
Biophysical Journal 114 (3), 18a, 2018
2018
Single-Molecule Activation by Flow: Force-Induced Conformational Transitions Regulate the Ligand Binding Affinity of a Large, Polymeric Mechanosensor Protein
H Fu, Y Jiang, D Yang, WP Wong, TA Springer
Biophysical Journal 110 (3), 348a, 2016
2016
Single-Molecule Imaging of Von Willebrand Factor Activation by Flow
Y Jiang, H Fu, D Yang, TA Springer, WP Wong
Biophysical Journal 106 (2), 194a, 2014
2014
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Статьи 1–13