| XPD helicase structures and activities: insights into the cancer and aging phenotypes from XPD mutations L Fan, JO Fuss, QJ Cheng, AS Arvai, M Hammel, VA Roberts, PK Cooper, ... Cell 133 (5), 789-800, 2008 | 415 | 2008 |
| Conserved XPB core structure and motifs for DNA unwinding: implications for pathway selection of transcription or excision repair L Fan, AS Arvai, PK Cooper, S Iwai, F Hanaoka, JA Tainer Molecular cell 22 (1), 27-37, 2006 | 180 | 2006 |
| Complex of linker histone H5 with the nucleosome and its implications for chromatin packing L Fan, VA Roberts Proceedings of the National Academy of Sciences 103 (22), 8384-8389, 2006 | 123 | 2006 |
| The accessory subunit of mtDNA polymerase shares structural homology with aminoacyl-tRNA synthetases: implications for a dual role as a primer recognition factor and … L Fan, PC Sanschagrin, LS Kaguni, LA Kuhn Proceedings of the National Academy of Sciences 96 (17), 9527-9532, 1999 | 113 | 1999 |
| The Potential Role of circRNA in Tumor Immunity Regulation and Immunotherapy WM Xu Z, Li P, Fan L Front Immunol., 2018 | 93 | 2018 |
| A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase L Fan, S Kim, CL Farr, KT Schaefer, KM Randolph, JA Tainer, LS Kaguni Journal of molecular biology 358 (5), 1229-1243, 2006 | 86 | 2006 |
| NMR crystallography of a carbanionic intermediate in tryptophan synthase: chemical structure, tautomerization, and reaction specificity BG Caulkins, RP Young, RA Kudla, C Yang, TJ Bittbauer, B Bastin, ... Journal of the American Chemical Society 138 (46), 15214-15226, 2016 | 76 | 2016 |
| A cytoplasmic long noncoding RNA LINC00470 as a new AKT activator to mediate glioblastoma cell autophagy WM Liu C, Zhang Y, She X, Fan L, Li P, Feng J, Fu H, Liu Q, Liu Q, Zhao C ... J Hematol Oncol. 11 (1), 77-87, 2018 | 74* | 2018 |
| Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair JJP Perry, L Fan, JA Tainer Neuroscience 145 (4), 1280-1299, 2007 | 70 | 2007 |
| Human resistin protects against endotoxic shock by blocking LPS-TLR4 interaction. NMG Jang JC, Li J, Gambini L, Batugedara HM, Sati S, Lazar MA, Fan L ... Proc Natl Acad Sci U S A. 114 (48), E10399-E10408, 2017 | 67* | 2017 |
| Protonation states of the tryptophan synthase internal aldimine active site from solid-state NMR spectroscopy: direct observation of the protonated Schiff base linkage to … BG Caulkins, B Bastin, C Yang, TJ Neubauer, RP Young, E Hilario, ... Journal of the American Chemical Society 136 (37), 12824-12827, 2014 | 66 | 2014 |
| Crystal structures of Xanthomonas small heat shock protein provide a structural basis for an active molecular chaperone oligomer E Hilario, FJM Martin, MC Bertolini, L Fan Journal of molecular biology 408 (1), 74-86, 2011 | 64 | 2011 |
| The nuclear transportation routes of membrane-bound transcription factors. WM Liu Y, Li P, Fan L Cell Commun Signal 16 (1), 12-18, 2018 | 63* | 2018 |
| Allostery and substrate channeling in the tryptophan synthase bienzyme complex: evidence for two subunit conformations and four quaternary states D Niks, E Hilario, A Dierkers, H Ngo, D Borchardt, TJ Neubauer, L Fan, ... Biochemistry 52 (37), 6396-6411, 2013 | 62 | 2013 |
| Amino acid substitution at the dimeric interface of human manganese superoxide dismutase AS Hearn, L Fan, JR Lepock, JP Luba, WB Greenleaf, DE Cabelli, ... Journal of Biological Chemistry 279 (7), 5861-5866, 2004 | 42 | 2004 |
| Visualizing the tunnel in tryptophan synthase with crystallography: Insights into a selective filter for accommodating indole and rejecting water E Hilario, BG Caulkins, YMM Huang, W You, CEA Chang, LJ Mueller, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1864 (3), 268-279, 2016 | 40 | 2016 |
| Novel Therapy for Glioblastoma Multiforme by Restoring LRRC4 in Tumor Cells: LRRC4 Inhibits Tumor-Infitrating Regulatory T Cells by Cytokine and Programmed Cell Death 1 … WM Li P, Feng J, Liu Y, Liu Q, Fan L, Liu Q, She X, Liu C, Liu T, Zhao C ... Front Immunol. 8, 1748-1756, 2017 | 39 | 2017 |
| XPB: an unconventional SF2 DNA helicase L Fan, KT DuPrez Progress in Biophysics and Molecular Biology 117 (2-3), 174-181, 2015 | 34 | 2015 |
| Structure of the C-terminal half of human XPB helicase and the impact of the disease-causing mutation XP11BE E Hilario, Y Li, Y Nobumori, X Liu, L Fan Acta Crystallographica Section D: Biological Crystallography 69 (2), 237-246, 2013 | 34 | 2013 |
| Multiple Regions of Subunit Interaction in Drosophila Mitochondrial DNA Polymerase: Three Functional Domains in the Accessory Subunit L Fan, LS Kaguni Biochemistry 40 (15), 4780-4791, 2001 | 29 | 2001 |
