| Structure of the human cytomegalovirus protease catalytic domain reveals a novel serine protease fold and catalytic triad P Chen, H Tsuge, RJ Almassy, CL Gribskov, S Katoh, DL Vanderpool, ... Cell 86 (5), 835-843, 1996 | 194 | 1996 |
| Crystal structure and site-directed mutagenesis of enzymatic components from Clostridium perfringens iota-toxin H Tsuge, M Nagahama, H Nishimura, J Hisatsune, Y Sakaguchi, ... Journal of molecular biology 325 (3), 471-483, 2003 | 138 | 2003 |
| Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo N Katunuma, E Murata, H Kakegawa, A Matsui, H Tsuzuki, H Tsuge, ... FEBS letters 458 (1), 6-10, 1999 | 138 | 1999 |
| Structural basis of actin recognition and arginine ADP-ribosylation by Clostridium perfringens ι-toxin H Tsuge, M Nagahama, M Oda, S Iwamoto, H Utsunomiya, VE Marquez, ... Proceedings of the National Academy of Sciences 105 (21), 7399-7404, 2008 | 134 | 2008 |
| Inhibition mechanism of cathepsin L-specific inhibitors based on the crystal structure of papain–CLIK148 complex H Tsuge, T Nishimura, Y Tada, T Asao, D Turk, V Turk, N Katunuma Biochemical and Biophysical Research Communications 266 (2), 411-416, 1999 | 132 | 1999 |
| Crystal structure of human D‐amino acid oxidase: context‐dependent variability of the backbone conformation of the VAAGL hydrophobic stretch located at the si‐face of the … T Kawazoe, H Tsuge, MS Pilone, K Fukui Protein science 15 (12), 2708-2717, 2006 | 128 | 2006 |
| Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue T Kuzuhara, D Kise, H Yoshida, T Horita, Y Murazaki, A Nishimura, ... Journal of Biological Chemistry 284 (11), 6855-6860, 2009 | 119 | 2009 |
| Identification of 16 novel mutations in the argininosuccinate synthetase gene and genotype–phenotype correlation in 38 classical citrullinemia patients HZ Gao, K Kobayashi, A Tabata, H Tsuge, M Iijima, T Yasuda, ... Human mutation 22 (1), 24-34, 2003 | 110 | 2003 |
| Structural basis of the sphingomyelin phosphodiesterase activity in neutral sphingomyelinase from Bacillus cereus H Ago, M Oda, M Takahashi, H Tsuge, S Ochi, N Katunuma, M Miyano, ... Journal of Biological Chemistry 281 (23), 16157-16167, 2006 | 104 | 2006 |
| The catalytic mechanism of dye‐decolorizing peroxidase DyP may require the swinging movement of an aspartic acid residue T Yoshida, H Tsuge, H Konno, T Hisabori, Y Sugano The FEBS journal 278 (13), 2387-2394, 2011 | 94 | 2011 |
| Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex T Tsurumura, Y Tsumori, H Qiu, M Oda, J Sakurai, M Nagahama, H Tsuge Proceedings of the National Academy of Sciences 110 (11), 4267-4272, 2013 | 93 | 2013 |
| Clostridium perfringens iota-toxin: structure and function J Sakurai, M Nagahama, M Oda, H Tsuge, K Kobayashi Toxins 1 (2), 208-228, 2009 | 90 | 2009 |
| Sequential Aldol Condensation Catalyzed by Hyperthermophilic 2-Deoxy-d-Ribose-5-Phosphate Aldolase H Sakuraba, K Yoneda, K Yoshihara, K Satoh, R Kawakami, Y Uto, ... Applied and environmental microbiology 73 (22), 7427-7434, 2007 | 87 | 2007 |
| Human D‐amino acid oxidase: an update and review T Kawazoe, HK Park, S Iwana, H Tsuge, K Fukui The Chemical Record 7 (5), 305-315, 2007 | 82 | 2007 |
| Structural basis of D-DOPA oxidation by D-amino acid oxidase: alternative pathway for dopamine biosynthesis T Kawazoe, H Tsuge, T Imagawa, K Aki, S Kuramitsu, K Fukui Biochemical and biophysical research communications 355 (2), 385-391, 2007 | 80 | 2007 |
| The calcium-binding property of equine lysozyme K Nitta, H Tsuge, S Sugai, K Shimazaki FEBS letters 223 (2), 405-408, 1987 | 80 | 1987 |
| Nucleolin as cell surface receptor for tumor necrosis factor-α inducing protein: a carcinogenic factor of Helicobacter pylori T Watanabe, H Tsuge, T Imagawa, D Kise, K Hirano, M Beppu, ... Journal of cancer research and clinical oncology 136, 911-921, 2010 | 78 | 2010 |
| Calcium-binding lysozymes K Nitta, H TSUGE, K SHIMAZAKI, S SUGAI Walter de Gruyter, Berlin/New York 369 (2), 671-676, 1988 | 69 | 1988 |
| Role of sphingomyelinase in infectious diseases caused by Bacillus cereus M Oda, M Hashimoto, M Takahashi, Y Ohmae, S Seike, R Kato, A Fujita, ... PloS one 7 (6), e38054, 2012 | 66 | 2012 |
| Expression and secretion of Mirabilis antiviral protein in Escherichia coli and its inhibition of in vitro eukaryotic and prokaryotic protein synthesis. N Habuka, K Akiyama, H Tsuge, M Miyano, T Matsumoto, M Noma Journal of Biological Chemistry 265 (19), 10988-10992, 1990 | 64 | 1990 |
