A Perspective–can copper complexes be developed as a novel class of therapeutics? M Wehbe, AWY Leung, MJ Abrams, C Orvig, MB Bally Dalton Transactions 46 (33), 10758-10773, 2017 | 177 | 2017 |
Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma L Wang-Bishop, M Wehbe, D Shae, J James, BC Hacker, K Garland, ... Journal for immunotherapy of cancer 8 (1), 2020 | 129 | 2020 |
Co-delivery of peptide neoantigens and stimulator of interferon genes agonists enhances response to cancer vaccines D Shae, JJ Baljon, M Wehbe, PP Christov, KW Becker, A Kumar, ... ACS nano 14 (8), 9904-9916, 2020 | 126 | 2020 |
Aptamers selected to postoperative lung adenocarcinoma detect circulating tumor cells in human blood GS Zamay, OS Kolovskaya, TN Zamay, YE Glazyrin, AV Krat, O Zubkova, ... Molecular Therapy 23 (9), 1486-1496, 2015 | 116 | 2015 |
Development of bacteriostatic DNA aptamers for salmonella OS Kolovskaya, AG Savitskaya, TN Zamay, IT Reshetneva, GS Zamay, ... Journal of medicinal chemistry 56 (4), 1564-1572, 2013 | 106 | 2013 |
Nanoparticle delivery improves the pharmacokinetic properties of cyclic dinucleotide STING agonists to open a therapeutic window for intravenous administration M Wehbe, L Wang-Bishop, KW Becker, D Shae, JJ Baljon, X He, ... Journal of Controlled Release 330, 1118-1129, 2021 | 81 | 2021 |
Development and optimization of an injectable formulation of copper diethyldithiocarbamate, an active anticancer agent M Wehbe, M Anantha, M Shi, AW Leung, WH Dragowska, L Sanche, ... International journal of nanomedicine, 4129-4146, 2017 | 61 | 2017 |
DNA-Aptamer Targeting Vimentin for Tumor Therapy In Vivo TN Zamay, OS Kolovskaya, YE Glazyrin, GS Zamay, SA Kuznetsova, ... nucleic acid therapeutics 24 (2), 160-170, 2014 | 60 | 2014 |
Nanoscale reaction vessels designed for synthesis of copper-drug complexes suitable for preclinical development M Wehbe, M Anantha, I Backstrom, A Leung, K Chen, A Malhotra, ... PloS one 11 (4), e0153416, 2016 | 55 | 2016 |
A simple passive equilibration method for loading carboplatin into pre-formed liposomes incubated with ethanol as a temperature dependent permeability enhancer M Wehbe, A Malhotra, M Anantha, J Roosendaal, AWY Leung, D Plackett, ... Journal of Controlled Release 252, 50-61, 2017 | 51 | 2017 |
Liposomal formulations of carboplatin injected by convection-enhanced delivery increases the median survival time of F98 glioma bearing rats M Shi, M Anantha, M Wehbe, MB Bally, D Fortin, LO Roy, G Charest, ... Journal of Nanobiotechnology 16, 1-12, 2018 | 45 | 2018 |
Copper (II) complexes of bidentate ligands exhibit potent anti-cancer activity regardless of platinum sensitivity status M Wehbe, C Lo, AWY Leung, WH Dragowska, GM Ryan, MB Bally Investigational new drugs 35 (6), 682-690, 2017 | 36 | 2017 |
Characterization of a liposomal copper (II)-quercetin formulation suitable for parenteral use KTJ Chen, M Anantha, AWY Leung, JA Kulkarni, GGC Militao, M Wehbe, ... Drug delivery and translational Research 10, 202-215, 2020 | 34 | 2020 |
STING-activating nanoparticles normalize the vascular-immune interface to potentiate cancer immunotherapy L Wang-Bishop, BR Kimmel, VM Ngwa, MZ Madden, JJ Baljon, ... Science immunology 8 (83), eadd1153, 2023 | 33 | 2023 |
Development of a copper-clioquinol formulation suitable for intravenous use M Wehbe, AK Malhotra, M Anantha, C Lo, WH Dragowska, N Dos Santos, ... Drug Delivery and Translational Research 8, 239-251, 2018 | 33 | 2018 |
At the bench: Engineering the next generation of cancer vaccines D Shae, JJ Baljon, M Wehbe, KW Becker, TL Sheehy, JT Wilson Journal of Leucocyte Biology 108 (4), 1435-1453, 2020 | 30 | 2020 |
Concomitant chemoradiation therapy with gold nanoparticles and platinum drugs co-encapsulated in liposomes G Charest, T Tippayamontri, M Shi, M Wehbe, M Anantha, M Bally, ... International Journal of Molecular Sciences 21 (14), 4848, 2020 | 29 | 2020 |
Switchable aptamers for biosensing and bioseparation of viruses (SwAps-V) M Wehbe, M Labib, D Muharemagic, AS Zamay, MV Berezovski Biosensors and Bioelectronics 67, 280-286, 2015 | 28 | 2015 |
The efficiency of cytosolic drug delivery using pH-responsive endosomolytic polymers does not correlate with activation of the NLRP3 inflammasome JJ Baljon, A Dandy, L Wang-Bishop, M Wehbe, ME Jacobson, JT Wilson Biomaterials science 7 (5), 1888-1897, 2019 | 24 | 2019 |
Viral quantitative capillary electrophoresis for counting and quality control of RNA viruses A Azizi, GG Mironov, D Muharemagic, M Wehbe, JC Bell, MV Berezovski Analytical chemistry 84 (21), 9585-9591, 2012 | 24 | 2012 |