| The human cathelicidin antimicrobial peptide LL-37 as a potential treatment for polymicrobial infected wounds AJ Duplantier, ML van Hoek Frontiers in immunology 4, 143, 2013 | 286 | 2013 |
| Biarylcarboxylic Acids and -amides: Inhibition of Phosphodiesterase Type IV versus [3H]Rolipram Binding Activity and Their Relationship to Emetic Behavior in … AJ Duplantier, MS Biggers, RJ Chambers, JB Cheng, K Cooper, ... Journal of medicinal chemistry 39 (1), 120-125, 1996 | 164 | 1996 |
| Discovery, SAR, and Pharmacokinetics of a Novel 3-Hydroxyquinolin-2(1H)-one Series of Potent d-Amino Acid Oxidase (DAAO) Inhibitors AJ Duplantier, SL Becker, MJ Bohanon, KA Borzilleri, BA Chrunyk, ... Journal of medicinal chemistry 52 (11), 3576-3585, 2009 | 130 | 2009 |
| Catechol diethers as selective PDEIV inhibitors AJ Duplantier, JF Eggler, A Marfat, H Masamune US Patent 5,814,651, 1998 | 101 | 1998 |
| Discovery of 4-(5-Methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a Novel α7 Nicotinic Acetylcholine Receptor Agonist for the … CJ O’Donnell, BN Rogers, BS Bronk, DK Bryce, JW Coe, KK Cook, ... Journal of medicinal chemistry 53 (3), 1222-1237, 2010 | 97 | 2010 |
| Nicotinamide derivatives A Marfat, RJ Chambers, JW Watson, JB Cheng, AJ Duplantier, ... US Patent 6,380,218, 2002 | 84 | 2002 |
| Mitigating the impact of antibacterial drug resistance through host-directed therapies: current progress, outlook, and challenges CY Chiang, I Uzoma, RT Moore, M Gilbert, AJ Duplantier, RG Panchal MBio 9 (1), 10.1128/mbio. 01932-17, 2018 | 72 | 2018 |
| Discovering drugs for the treatment of Ebola virus SL Bixler, AJ Duplantier, S Bavari Current Treatment Options in Infectious Diseases 9, 299-317, 2017 | 71 | 2017 |
| Optimization of the physicochemical and pharmacokinetic attributes in a 6-azauracil series of P2X7 receptor antagonists leading to the discovery of the clinical candidate CE … AJ Duplantier, MA Dombroski, C Subramanyam, AM Beaulieu, SP Chang, ... Bioorganic & medicinal chemistry letters 21 (12), 3708-3711, 2011 | 70 | 2011 |
| Triple asymmetric synthesis for fragment assembly: validity of approximate multiplicativity of the three diastereofacial selectivities AJ Duplantier, MH Nantz, JC Roberts, RP Short, P Somfai, S Masamune Tetrahedron letters 30 (52), 7357-7360, 1989 | 67 | 1989 |
| Pulmonary eosinophilia in a murine model of allergic inflammation is attenuated by small molecule α4β1 antagonists E Kudlacz, C Whitney, C Andresen, A Duplantier, G Beckius, L Chupak, ... Journal of Pharmacology and Experimental Therapeutics 301 (2), 747-752, 2002 | 62 | 2002 |
| Triazolo-pyridines anti-inflammatory compounds KF McClure, MA Letavic, MA Dombroski, AJ Duplantier, ER Laird US Patent 6,696,464, 2004 | 60 | 2004 |
| Recent successes in therapeutics for Ebola virus disease: no time for complacency PL Iversen, CD Kane, X Zeng, RG Panchal, TK Warren, SR Radoshitzky, ... The Lancet Infectious diseases 20 (9), e231-e237, 2020 | 52 | 2020 |
| Pimaricin. Stereochemistry and synthesis of its aglycon (pimarolide) methyl ester AJ Duplantier, S Masamune Journal of the American Chemical Society 112 (19), 7079-7081, 1990 | 51 | 1990 |
| Synthesis and in vitro profile of a novel series of catechol benzimidazoles. The discovery of potent, selective phosphodiesterase type IV inhibitors with greatly attenuated … JB Cheng, K Cooper, AJ Duplantier, JF Eggler, KG Kraus, SC Marshall, ... Bioorganic & Medicinal Chemistry Letters 5 (17), 1969-1972, 1995 | 50 | 1995 |
| 7-Oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridines as Novel Inhibitors of Human Eosinophil Phosphodiesterase AJ Duplantier, CJ Andresen, JB Cheng, VL Cohan, C Decker, ... Journal of medicinal chemistry 41 (13), 2268-2277, 1998 | 47 | 1998 |
| 1-[(1-Methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 Positive Allosteric Modulators for the Treatment of Psychosis L Zhang, MA Brodney, J Candler, AC Doran, AJ Duplantier, IV Efremov, ... Journal of medicinal chemistry 54 (6), 1724-1739, 2011 | 43 | 2011 |
| Modulation of NMDA receptor function by inhibition of D-amino acid oxidase in rodent brain CA Strick, C Li, L Scott, B Harvey, M Hajós, SJ Steyn, MA Piotrowski, ... Neuropharmacology 61 (5-6), 1001-1015, 2011 | 42 | 2011 |
| Non-peptidyl inhibitors of VLA-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases AJ Duplantier, LS Chupak, AJ Milici, WF Lau US Patent 6,668,527, 2003 | 41 | 2003 |
| Benzimidazolyl compounds I Efremov, BN Rogers, AJ Duplantier, L Zhang, Q Zhang, NS Maklad, ... US Patent App. 11/780,579, 2008 | 40 | 2008 |
Monique van HoekSchool of Systems Biology, Center for Infectious Disease Research, George Mason UniversityПодтвержден адрес электронной почты в домене gmu.edu
