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Goptar Irina
Goptar Irina
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Orthologous CRISPR/Cas9 systems for specific and efficient degradation of covalently closed circular DNA of hepatitis B virus
D Kostyushev, S Brezgin, A Kostyusheva, D Zarifyan, I Goptar, ...
Cellular and molecular life sciences 76 (9), 1779-1794, 2019
702019
Suppressing the NHEJ pathway by DNA-PKcs inhibitor NU7026 prevents degradation of HBV cccDNA cleaved by CRISPR/Cas9
D Kostyushev, A Kostyusheva, S Brezgin, D Zarifyan, A Utkina, I Goptar, ...
Scientific reports 9 (1), 1847, 2019
492019
Cysteine digestive peptidases function as post-glutamine cleaving enzymes in tenebrionid stored-product pests
IA Goptar, TA Semashko, SA Danilenko, EN Lysogorskaya, ES Oksenoit, ...
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular …, 2012
432012
Whole genome sequencing of Borrelia miyamotoi isolate Izh-4: reference for a complex bacterial genome
KV Kuleshov, G Margos, V Fingerle, J Koetsveld, IA Goptar, ML Markelov, ...
BMC genomics 21, 1-18, 2020
352020
Digestive peptidases in Tenebrio molitor and possibility of use to treat celiac disease
EN Elpidina, IA Goptar
Entomological Research 37 (3), 139-147, 2007
322007
Dipeptidyl peptidase 4–an important digestive peptidase in Tenebrio molitor larvae
VF Tereshchenkova, IA Goptar, IA Kulemzina, DP Zhuzhikov, ...
Insect biochemistry and molecular biology 76, 38-48, 2016
252016
A digestive prolyl carboxypeptidase in Tenebrio molitor larvae
IA Goptar, DA Shagin, IA Shagina, ES Mudrik, YA Smirnova, ...
Insect Biochemistry and Molecular Biology 43 (6), 501-509, 2013
252013
ATM and ATR expression potentiates HBV replication and contributes to reactivation of HBV infection upon DNA damage
A Kostyusheva, S Brezgin, E Bayurova, I Gordeychuk, M Isaguliants, ...
Viruses 11 (11), 997, 2019
182019
Whole-Genome Sequencing of Six Borrelia miyamotoi Clinical Strains Isolated in Russia
KV Kuleshov, J Koetsveld, IA Goptar, ML Markelov, NM Kolyasnikova, ...
Genome announcements 6 (1), 10.1128/genomea. 01424-17, 2018
172018
Replenishment of hepatitis B virus cccDNA pool is restricted by baseline expression of host restriction factors in vitro
S Brezgin, A Kostyusheva, E Bayurova, I Gordeychuk, M Isaguliants, ...
Microorganisms 7 (11), 533, 2019
142019
Localization of post-proline cleaving peptidases in Tenebrio molitor larval midgut
IA Goptar, IY Filippova, EN Lysogorskaya, ES Oksenoit, KS Vinokurov, ...
Biochimie 90 (3), 508-514, 2008
142008
Prolidase is a critical enzyme for complete gliadin digestion in Tenebrio molitor larvae
VF Tereshchenkova, IA Goptar, DP Zhuzhikov, MA Belozersky, ...
Archives of Insect Biochemistry and Physiology 95 (4), e21395, 2017
122017
Depleting hepatitis B virus relaxed circular DNA is necessary for resolution of infection by CRISPR-Cas9
D Kostyushev, A Kostyusheva, S Brezgin, N Ponomareva, NF Zakirova, ...
Molecular Therapy-Nucleic Acids 31, 482-493, 2023
82023
Clearing of foreign episomal DNA from human cells by CRISPRa-mediated activation of cytidine deaminases
S Brezgin, A Kostyusheva, N Ponomareva, V Volia, I Goptar, A Nikiforova, ...
International journal of molecular sciences 21 (18), 6865, 2020
82020
Properties of post-proline cleaving enzymes from Tenebrio molitor
IA Goptar, IA Koulemzina, IY Filippova, EN Lysogorskaya, ES Oksenoit, ...
Russian Journal of Bioorganic Chemistry 34, 280-285, 2008
82008
Evaluation of the population heterogeneity of TBEV laboratory variants using high-throughput sequencing
AG Litov, AA Deviatkin, IA Goptar, VG Dedkov, AP Gmyl, ML Markelov, ...
Journal of General Virology 99 (2), 240-245, 2018
62018
Characteristic of Neisseria meningitidis serogroup W circulating in the territory of Moscow, using mass parallel sequencing
KO Mironov, VA Zhivotova, SV Matosova, KV Kuleshov, OY Shipulina, ...
Epidemiologiya i vaktsinoprofilaktika (Epidemiology and Vaccinal Prevention …, 2017
62017
Transient and tunable CRISPRa regulation of APOBEC/AID genes for targeting hepatitis B virus
D Kostyushev, S Brezgin, A Kostyusheva, N Ponomareva, E Bayurova, ...
Molecular Therapy-Nucleic Acids 32, 478-493, 2023
52023
First verified case of hereditary transmission of chromosomally integrated Human betaherpesvirus 6B
EV Melekhina, EA Domonova, IA Goptar, OY Shipulina, AV Gorelov
Вопросы практической педиатрии 14 (1), 33-40, 2019
42019
First data on the prevalence of inherited chromosomally integrated Human betaherpesvirus 6A/B in Russia
EA Domonova, OY Silveistrova, IA Goptar, KV Kuleshov, AV Nikiforova, ...
Epidemiology and infectious diseases. Current items 9 (4), 43-50, 2019
32019
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