Orthologous CRISPR/Cas9 systems for specific and efficient degradation of covalently closed circular DNA of hepatitis B virus D Kostyushev, S Brezgin, A Kostyusheva, D Zarifyan, I Goptar, ... Cellular and molecular life sciences 76 (9), 1779-1794, 2019 | 70 | 2019 |
Suppressing the NHEJ pathway by DNA-PKcs inhibitor NU7026 prevents degradation of HBV cccDNA cleaved by CRISPR/Cas9 D Kostyushev, A Kostyusheva, S Brezgin, D Zarifyan, A Utkina, I Goptar, ... Scientific reports 9 (1), 1847, 2019 | 49 | 2019 |
Cysteine digestive peptidases function as post-glutamine cleaving enzymes in tenebrionid stored-product pests IA Goptar, TA Semashko, SA Danilenko, EN Lysogorskaya, ES Oksenoit, ... Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular …, 2012 | 43 | 2012 |
Whole genome sequencing of Borrelia miyamotoi isolate Izh-4: reference for a complex bacterial genome KV Kuleshov, G Margos, V Fingerle, J Koetsveld, IA Goptar, ML Markelov, ... BMC genomics 21, 1-18, 2020 | 35 | 2020 |
Digestive peptidases in Tenebrio molitor and possibility of use to treat celiac disease EN Elpidina, IA Goptar Entomological Research 37 (3), 139-147, 2007 | 32 | 2007 |
Dipeptidyl peptidase 4–an important digestive peptidase in Tenebrio molitor larvae VF Tereshchenkova, IA Goptar, IA Kulemzina, DP Zhuzhikov, ... Insect biochemistry and molecular biology 76, 38-48, 2016 | 25 | 2016 |
A digestive prolyl carboxypeptidase in Tenebrio molitor larvae IA Goptar, DA Shagin, IA Shagina, ES Mudrik, YA Smirnova, ... Insect Biochemistry and Molecular Biology 43 (6), 501-509, 2013 | 25 | 2013 |
ATM and ATR expression potentiates HBV replication and contributes to reactivation of HBV infection upon DNA damage A Kostyusheva, S Brezgin, E Bayurova, I Gordeychuk, M Isaguliants, ... Viruses 11 (11), 997, 2019 | 18 | 2019 |
Whole-Genome Sequencing of Six Borrelia miyamotoi Clinical Strains Isolated in Russia KV Kuleshov, J Koetsveld, IA Goptar, ML Markelov, NM Kolyasnikova, ... Genome announcements 6 (1), 10.1128/genomea. 01424-17, 2018 | 17 | 2018 |
Replenishment of hepatitis B virus cccDNA pool is restricted by baseline expression of host restriction factors in vitro S Brezgin, A Kostyusheva, E Bayurova, I Gordeychuk, M Isaguliants, ... Microorganisms 7 (11), 533, 2019 | 14 | 2019 |
Localization of post-proline cleaving peptidases in Tenebrio molitor larval midgut IA Goptar, IY Filippova, EN Lysogorskaya, ES Oksenoit, KS Vinokurov, ... Biochimie 90 (3), 508-514, 2008 | 14 | 2008 |
Prolidase is a critical enzyme for complete gliadin digestion in Tenebrio molitor larvae VF Tereshchenkova, IA Goptar, DP Zhuzhikov, MA Belozersky, ... Archives of Insect Biochemistry and Physiology 95 (4), e21395, 2017 | 12 | 2017 |
Depleting hepatitis B virus relaxed circular DNA is necessary for resolution of infection by CRISPR-Cas9 D Kostyushev, A Kostyusheva, S Brezgin, N Ponomareva, NF Zakirova, ... Molecular Therapy-Nucleic Acids 31, 482-493, 2023 | 8 | 2023 |
Clearing of foreign episomal DNA from human cells by CRISPRa-mediated activation of cytidine deaminases S Brezgin, A Kostyusheva, N Ponomareva, V Volia, I Goptar, A Nikiforova, ... International journal of molecular sciences 21 (18), 6865, 2020 | 8 | 2020 |
Properties of post-proline cleaving enzymes from Tenebrio molitor IA Goptar, IA Koulemzina, IY Filippova, EN Lysogorskaya, ES Oksenoit, ... Russian Journal of Bioorganic Chemistry 34, 280-285, 2008 | 8 | 2008 |
Evaluation of the population heterogeneity of TBEV laboratory variants using high-throughput sequencing AG Litov, AA Deviatkin, IA Goptar, VG Dedkov, AP Gmyl, ML Markelov, ... Journal of General Virology 99 (2), 240-245, 2018 | 6 | 2018 |
Characteristic of Neisseria meningitidis serogroup W circulating in the territory of Moscow, using mass parallel sequencing KO Mironov, VA Zhivotova, SV Matosova, KV Kuleshov, OY Shipulina, ... Epidemiologiya i vaktsinoprofilaktika (Epidemiology and Vaccinal Prevention …, 2017 | 6 | 2017 |
Transient and tunable CRISPRa regulation of APOBEC/AID genes for targeting hepatitis B virus D Kostyushev, S Brezgin, A Kostyusheva, N Ponomareva, E Bayurova, ... Molecular Therapy-Nucleic Acids 32, 478-493, 2023 | 5 | 2023 |
First verified case of hereditary transmission of chromosomally integrated Human betaherpesvirus 6B EV Melekhina, EA Domonova, IA Goptar, OY Shipulina, AV Gorelov Вопросы практической педиатрии 14 (1), 33-40, 2019 | 4 | 2019 |
First data on the prevalence of inherited chromosomally integrated Human betaherpesvirus 6A/B in Russia EA Domonova, OY Silveistrova, IA Goptar, KV Kuleshov, AV Nikiforova, ... Epidemiology and infectious diseases. Current items 9 (4), 43-50, 2019 | 3 | 2019 |