Quinolone-3-diarylethers: a new class of antimalarial drug A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ... Science translational medicine 5 (177), 177ra37-177ra37, 2013 | 248 | 2013 |
The Transmembrane Isoform of Plasmodium falciparum MAEBL Is Essential for the Invasion of Anopheles Salivary Glands FE Saenz, B Balu, J Smith, SR Mendonca, JH Adams PloS one 3 (5), e2287, 2008 | 61 | 2008 |
Malaria epidemiology in low-endemicity areas of the northern coast of Ecuador: high prevalence of asymptomatic infections FE Sáenz, A Arévalo-Cortés, G Valenzuela, AF Vallejo, A Castellanos, ... Malaria journal 16, 1-10, 2017 | 51 | 2017 |
Orally Bioavailable 6-Chloro-7-methoxy-4(1H)-quinolones Efficacious against Multiple Stages of Plasmodium RM Cross, DL Flanigan, A Monastyrskyi, AN LaCrue, FE Sáenz, ... Journal of Medicinal Chemistry 57 (21), 8860-8879, 2014 | 42 | 2014 |
4(1H)-Quinolones with Liver Stage Activity against Plasmodium berghei AN LaCrue, FE Sáenz, RM Cross, KO Udenze, A Monastyrskyi, S Stein, ... Antimicrobial agents and chemotherapy 57 (1), 417-424, 2013 | 42 | 2013 |
Novel 4-Aminoquinoline Analogs Highly Active against the Blood and Sexual Stages of Plasmodium In Vivo and In Vitro FE Sáenz, T Mutka, K Udenze, AMJ Oduola, DE Kyle Antimicrobial agents and chemotherapy 56 (9), 4685-4692, 2012 | 41 | 2012 |
Clonal population expansion in an outbreak of Plasmodium falciparum on the northwest coast of Ecuador FE Sáenz, LC Morton, SA Okoth, G Valenzuela, CA Vera-Arias, ... Malaria journal 14, 1-10, 2015 | 38 | 2015 |
4-(1H)-Quinolones and 1,2,3,4-Tetrahydroacridin-9(10H)-Ones Prevent the Transmission of Plasmodium falciparum to Anopheles freeborni FE Sáenz, AN LaCrue, RM Cross, JR Maignan, KO Udenze, R Manetsch, ... Antimicrobial agents and chemotherapy 57 (12), 6187-6195, 2013 | 27 | 2013 |
High-throughput Plasmodium falciparum hrp2 and hrp3 gene deletion typing by digital PCR to monitor malaria rapid diagnostic test efficacy CA Vera-Arias, A Holzschuh, CO Oduma, K Badu, M Abdul-Hakim, ... Elife 11, e72083, 2022 | 26 | 2022 |
The relative role of climate variation and control interventions on malaria elimination efforts in El Oro, Ecuador: a modeling study IK Fletcher, AM Stewart-Ibarra, R Sippy, G Carrasco-Escobar, M Silva, ... Frontiers in Environmental Science 8, 135, 2020 | 20 | 2020 |
Diverse origin of Plasmodium falciparum in northwest Ecuador CA Vera-Arias, LE Castro, J Gómez-Obando, FE Sáenz Malaria journal 18, 1-11, 2019 | 19 | 2019 |
Quinolone-3-diarylethers: a new class of antimalarial drug. Sci Transl Med 5: 177ra37 A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ... | 19 | 2013 |
Anopheline and human drivers of malaria risk in northern coastal, Ecuador: a pilot study JA Martin, AL Hendershot, IA Saá Portilla, DJ English, M Woodruff, ... Malaria Journal 19, 1-11, 2020 | 18 | 2020 |
Evidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model PP Henrich, C O'Brien, FE Sáenz, S Cremers, DE Kyle, DA Fidock Antimicrobial agents and chemotherapy 58 (1), 183-195, 2014 | 17 | 2014 |
Targeted disruption of maebl in Plasmodium falciparum J Fu, FE Sáenz, MB Reed, B Balu, N Singh, PL Blair, AF Cowman, ... Molecular and biochemical parasitology 141 (1), 113, 2005 | 16 | 2005 |
Lamina-associated polypeptide 2 (LAP2) expression in fish and amphibians. EM Del-Pino, FE Saenz, OD Perez, FD Brown, ME Avila, VA Barragan, ... International Journal of Developmental Biology 46 (2), 227-234, 2002 | 13 | 2002 |
Resolving drug selection and migration in an inbred South American Plasmodium falciparum population with identity-by-descent analysis M Carrasquilla, AM Early, AR Taylor, A Knudson Ospina, DF Echeverry, ... PLoS pathogens 18 (12), e1010993, 2022 | 11 | 2022 |
Clinical malaria incidence following an outbreak in Ecuador was predominantly associated with Plasmodium falciparum with recombinant variant antigen gene … S Ruybal-Pesántez, FE Sáenz, S Deed, EK Johnson, DB Larremore, ... MedRxiv, 2021.04. 12.21255093, 2021 | 10 | 2021 |
Genotypes and phenotypes of resistance in Ecuadorian Plasmodium falciparum G Valenzuela, LE Castro, J Valencia-Zamora, CA Vera-Arias, P Rohrbach, ... Malaria Journal 18, 1-13, 2019 | 10 | 2019 |
Molecular epidemiology of continued Plasmodium falciparum disease transmission after an outbreak in Ecuador S Ruybal-Pesántez, FE Sáenz, SL Deed, EK Johnson, DB Larremore, ... Frontiers in Tropical Diseases 4, 1085862, 2023 | 5 | 2023 |