Comprehensive study of the drug delivery properties of poly (l-lactide)-poly (ethylene glycol) nanoparticles in rats and tumor-bearing mice V Shalgunov, D Zaytseva-Zotova, A Zintchenko, T Levada, Y Shilov, ... Journal of Controlled Release 261, 31-42, 2017 | 72 | 2017 |
Modulation of F0F1‐ATP synthase activity by cyclophilin D regulates matrix adenine nucleotide levels C Chinopoulos, C Konràd, G Kiss, E Metelkin, B Töröcsik, SF Zhang, ... The FEBS journal 278 (7), 1112-1125, 2011 | 72 | 2011 |
Mathematical modeling of mitochondrial adenine nucleotide translocase E Metelkin, I Goryanin, O Demin Biophysical Journal 90 (2), 423-432, 2006 | 61 | 2006 |
Modeling of ATP–ADP steady‐state exchange rate mediated by the adenine nucleotide translocase in isolated mitochondria E Metelkin, O Demin, Z Kovács, C Chinopoulos The FEBS journal 276 (23), 6942-6955, 2009 | 58 | 2009 |
DBSolve Optimum: a software package for kinetic modeling which allows dynamic visualization of simulation results NM Gizzatkulov, II Goryanin, EA Metelkin, EA Mogilevskaya, KV Peskov, ... BMC systems biology 4, 1-11, 2010 | 54 | 2010 |
A systems pharmacology perspective on the clinical development of fatty acid amide hydrolase inhibitors for pain N Benson, E Metelkin, O Demin, GL Li, D Nichols, PH Van Der Graaf CPT: pharmacometrics & systems pharmacology 3 (1), 1-7, 2014 | 28 | 2014 |
Systems pharmacology models can be used to understand complex pharmacokinetic‐pharmacodynamic behavior: an example using 5‐lipoxygenase inhibitors O Demin, T Karelina, D Svetlichniy, E Metelkin, G Speshilov, O Demin Jr, ... CPT: Pharmacometrics & Systems Pharmacology 2 (9), 1-9, 2013 | 26 | 2013 |
Kinetic modeling as a tool to integrate multilevel dynamic experimental data E Mogilevskaya, N Bagrova, T Plyusnina, N Gizzatkulov, E Metelkin, ... Protein Networks and Pathway Analysis, 197-218, 2009 | 24 | 2009 |
Confidence intervals by constrained optimization—An algorithm and software package for practical identifiability analysis in systems biology I Borisov, E Metelkin PLOS Computational Biology 16 (12), e1008495, 2020 | 16 | 2020 |
Kinetic modelling of the E. coli metabolism OV Demin, TY Plyusnina, GV Lebedeva, EA Zobova, EA Metelkin, ... Systems Biology: Definitions and Perspectives, 31-67, 2005 | 12 | 2005 |
Cellular kinetic modeling of the microbial metabolism II Goryanin, GV Lebedeva, EA Mogilevskaya, EA Metelkin, OV Demin Microbial Proteomics: Functional Biology of Whole Organisms, 437-488, 2006 | 10 | 2006 |
Comparison of asymptotic confidence sets for regression in small samples D Kolobkov, O Demin, E Metelkin Journal of Biopharmaceutical Statistics 26 (4), 742-757, 2016 | 4 | 2016 |
Kinetic Modeling of E. coli Enzymes: Integration of in vitro Experimental Data EA Mogilevskaya, KV Peskov, EA Metelkin, GV Lebedeva, TY Plyusnina, ... Systems Biology and Biotechnology of Escherichia coli, 177-207, 2009 | 3 | 2009 |
A kinetic model of Escherichia coli β-galactosidase EA Metelkin, GV Lebedeva, II Goryanin, OV Demin Biophysics 54, 156-162, 2009 | 2 | 2009 |
A kinetic model of beta-galactosidase of Escherichia coli EA Metelkin, GV Lebedeva, II Gorianin, OV Demin Biofizika 54 (2), 226-234, 2009 | 1 | 2009 |
PBPK MODELING FOR THERAPEUTIC NANOPARTICLES LOADED WITH DRUG: DISTRIBUTION AND RELEASE. E Metelkin, O Demin CLINICAL PHARMACOLOGY & THERAPEUTICS 103, S11-S12, 2018 | | 2018 |
MECHANISTIC MODELING OF CELL DYNAMICS: NEUTROPHILS SURVIVAL IN THE PRESENCE OF PRO-INFLAMMATORY CYTOKINES E Metelkin CLINICAL PHARMACOLOGY & THERAPEUTICS 101 (S 1), S78-S79, 2017 | | 2017 |
MECHANISTIC MODELING OF CELL DYNAMICS: EFFECT OF COSTIMULATORY AND CO-INHIBITORY SURFACE MOLECULES ON PROCESSES ASSOCIATED WITH CELL-TO-CELL INTERACTIONS O Demin Jr, E Metelkin, O Demin CLINICAL PHARMACOLOGY & THERAPEUTICS 101 (S 1), S62-S62, 2017 | | 2017 |
MECHANISTIC MODEL OF NEUTROPHIL CELL DYNAMICS AND ACTIVATION TO INFORM SYSTEMS PHARMACOLOGY MODELING OF THE IMMUNE RESPONSE. G Lebedeva, S Smirnov, E Metelkin, O Demin CLINICAL PHARMACOLOGY & THERAPEUTICS 101 (S 1), S72-S72, 2017 | | 2017 |
MECHANISTIC MODEL OF MAST CELL LIFE CYCLE, ACTIVATION AND RELEASE OF BIOACTIVE MOLECULES DESIGNED TO SUPPORT SYSTEMS PHARMACOLOGY MODELING OF THE IMMUNE RESPONSE. G Lebedeva, S Smirnov, E Metelkin, O Demin CLINICAL PHARMACOLOGY & THERAPEUTICS 101 (S 1), S72-S72, 2017 | | 2017 |