| Functional interaction of β-catenin with the transcription factor LEF-1 J Behrens, JP Von Kries, M Kühl, L Bruhn, D Wedlich, R Grosschedl, ... Nature 382 (6592), 638-642, 1996 | 3934 | 1996 |
| Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. C van Genderen, RM Okamura, I Farinas, RG Quo, TG Parslow, L Bruhn, ... Genes & development 8 (22), 2691-2703, 1994 | 1210 | 1994 |
| HMG domain proteins: architectural elements in the assembly of nucleoprotein structures R Grosschedl, K Giese, J Pagel Trends in Genetics 10 (3), 94-100, 1994 | 1073 | 1994 |
| Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice AS Tsukamoto, R Grosschedl, RC Guzman, T Parslow, HE Varmus Cell 55 (4), 619-625, 1988 | 932 | 1988 |
| The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures K Giese, J Cox, R Grosschedl Cell 69 (1), 185-195, 1992 | 865 | 1992 |
| Failure of B-cell differentiation in mice lacking the transcription factor EBF H Lin, R Grosschedl Nature 376 (6537), 263-267, 1995 | 854 | 1995 |
| LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected] A Travis, A Amsterdam, C Belanger, R Grosschedl Genes & development 5 (5), 880-894, 1991 | 778 | 1991 |
| Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma J Okosun, C Bödör, J Wang, S Araf, CY Yang, C Pan, S Boller, D Cittaro, ... Nature genetics 46 (2), 176-181, 2014 | 776 | 2014 |
| Regulation of LEF-1/TCF transcription factors by Wnt and other signals Q Eastman, R Grosschedl Current opinion in cell biology 11 (2), 233-240, 1999 | 758 | 1999 |
| Structural basis for DNA bending by the architectural transcription factor LEF-1 JJ Love, X Li, DA Case, K Giese, R Grosschedl, PE Wright Nature 376 (6543), 791-795, 1995 | 749 | 1995 |
| Satb2 regulates callosal projection neuron identity in the developing cerebral cortex EA Alcamo, L Chirivella, M Dautzenberg, G Dobreva, I Fariñas, ... Neuron 57 (3), 364-377, 2008 | 721 | 2008 |
| Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions. K Giese, C Kingsley, JR Kirshner, R Grosschedl Genes & development 9 (8), 995-1008, 1995 | 710 | 1995 |
| PIASy, a nuclear matrix–associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies S Sachdev, L Bruhn, H Sieber, A Pichler, F Melchior, R Grosschedl Genes & development 15 (23), 3088-3103, 2001 | 681 | 2001 |
| Cell-type specificity of iminunoglobulin gene expression is regulated by at least three DNA sequence elements R Grosschedl, DB Whitehead Cell 41 (3), 885-897, 1985 | 635 | 1985 |
| SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation G Dobreva, M Chahrour, M Dautzenberg, L Chirivella, B Kanzler, I Fariñas, ... Cell 125 (5), 971-986, 2006 | 615 | 2006 |
| Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo. R Grosschedl, ML Birnstiel Proceedings of the National Academy of Sciences 77 (3), 1432-1436, 1980 | 609 | 1980 |
| Cell adhesion and the integrin-linked kinase regulate the LEF-1 and β-catenin signaling pathways A Novak, SC Hsu, C Leung-Hagesteijn, G Radeva, J Papkoff, ... Proceedings of the National Academy of Sciences 95 (8), 4374-4379, 1998 | 587 | 1998 |
| Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism T Reya, M O'Riordan, R Okamura, E Devaney, K Willert, R Nusse, ... Immunity 13 (1), 15-24, 2000 | 575 | 2000 |
| Dynamics and interplay of nuclear architecture, genome organization, and gene expression R Schneider, R Grosschedl Genes & development 21 (23), 3027-3043, 2007 | 562 | 2007 |
| Wnt3a−/−-like phenotype and limb deficiency in Lef1−/− Tcf1−/− mice J Galceran, I Farinas, MJ Depew, H Clevers, R Grosschedl Genes & development 13 (6), 709-717, 1999 | 558 | 1999 |
Isabel FariñasFull Professor in Cell Biology, Universidad de ValenciaVerified email at uv.es
