| Stimulation of human and rat islet β-cell proliferation with retention of function by the homeodomain transcription factor Nkx6. 1 JC Schisler, PT Fueger, DA Babu, HE Hohmeier, JS Tessem, D Lu, ... Molecular and cellular biology 28 (10), 3465-3476, 2008 | 130 | 2008 |
| Nkx6. 1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors JS Tessem, LG Moss, LC Chao, M Arlotto, D Lu, MV Jensen, SB Stephens, ... Proceedings of the National Academy of Sciences 111 (14), 5242-5247, 2014 | 103 | 2014 |
| The development of diabetes in E2f1/E2f2 mutant mice reveals important roles for bone marrow-derived cells in preventing islet cell loss FX Li, JW Zhu, JS Tessem, J Beilke, M Varella-Garcia, J Jensen, ... Proceedings of the National Academy of Sciences 100 (22), 12935-12940, 2003 | 101 | 2003 |
| Function of Nr4a orphan nuclear receptors in proliferation, apoptosis and fuel utilization across tissues JA Herring, WS Elison, JS Tessem Cells 8 (11), 1373, 2019 | 97 | 2019 |
| Mechanisms by which cocoa flavanols improve metabolic syndrome and related disorders KM Strat, TJ Rowley IV, AT Smithson, JS Tessem, MW Hulver, D Liu, ... The Journal of nutritional biochemistry 35, 1-21, 2016 | 92 | 2016 |
| Monomeric cocoa catechins enhance β-cell function by increasing mitochondrial respiration TJ Rowley IV, BF Bitner, JD Ray, DR Lathen, AT Smithson, BW Dallon, ... The Journal of nutritional biochemistry 49, 30-41, 2017 | 70 | 2017 |
| Critical roles for macrophages in islet angiogenesis and maintenance during pancreatic degeneration JS Tessem, JN Jensen, H Pelli, XM Dai, XH Zong, ER Stanley, J Jensen, ... Diabetes 57 (6), 1605-1617, 2008 | 61 | 2008 |
| Common gut microbial metabolites of dietary flavonoids exert potent protective activities in β-cells and skeletal muscle cells BF Bitner, JD Ray, KB Kener, JA Herring, JA Tueller, DK Johnson, ... The Journal of nutritional biochemistry 62, 95-107, 2018 | 56 | 2018 |
| Nkx6. 1‐mediated insulin secretion and β‐cell proliferation is dependent on upregulation of c‐Fos JD Ray, KB Kener, BF Bitner, BJ Wright, MS Ballard, EJ Barrett, JT Hill, ... FEBS letters 590 (12), 1791-1803, 2016 | 44 | 2016 |
| β-Cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion MS Reynolds, CR Hancock, JD Ray, KB Kener, C Draney, K Garland, ... American Journal of Physiology-Endocrinology and Metabolism 311 (1), E186-E201, 2016 | 42 | 2016 |
| β-hydroxybutyrate elicits favorable mitochondrial changes in skeletal muscle BA Parker, CM Walton, ST Carr, JL Andrus, ECK Cheung, MJ Duplisea, ... International journal of molecular sciences 19 (8), 2247, 2018 | 41 | 2018 |
| Aurora Kinase A is critical for the Nkx6. 1 mediated β-cell proliferation pathway A Hobson, C Draney, A Stratford, TC Becker, D Lu, M Arlotto, JS Tessem Islets 7 (1), e1027854, 2015 | 32 | 2015 |
| The accumulation and molecular effects of trimethylamine N-oxide on metabolic tissues: It’s not all bad ES Krueger, TS Lloyd, JS Tessem Nutrients 13 (8), 2873, 2021 | 28 | 2021 |
| Acylation of superoxide dismutase 1 (SOD1) at K122 governs SOD1-mediated inhibition of mitochondrial respiration CJ Banks, NW Rodriguez, KR Gashler, RR Pandya, JB Mortenson, ... Molecular and Cellular Biology 37 (20), e00354-17, 2017 | 27 | 2017 |
| Cdk5r1 overexpression induces primary β-cell proliferation C Draney, AE Hobson, SG Grover, BO Jack, JS Tessem Journal of diabetes research 2016, 2016 | 26 | 2016 |
| Good cop, bad cop: the opposing effects of macrophage activation state on maintaining or damaging functional β-cell mass DM Jensen, KV Hendricks, AT Mason, JS Tessem Metabolites 10 (12), 485, 2020 | 22 | 2020 |
| Identification of direct transcriptional targets of NFATC2 that promote β cell proliferation SP Simonett, S Shin, JA Herring, R Bacher, LA Smith, C Dong, ... The Journal of clinical investigation 131 (21), 2021 | 16 | 2021 |
| HDAC1 overexpression enhances β-cell proliferation by down-regulating Cdkn1b/p27 C Draney, MC Austin, AH Leifer, CJ Smith, KB Kener, TJ Aitken, KH Hess, ... Biochemical Journal 475 (24), 3997-4010, 2018 | 14 | 2018 |
| Gut metabolite trimethylamine n-oxide protects INS-1 β-cell and rat islet function under diabetic glucolipotoxic conditions ES Krueger, JL Beales, KB Russon, WS Elison, JR Davis, JM Hansen, ... Biomolecules 11 (12), 1892, 2021 | 13 | 2021 |
| Diet-induced obesity in genetically diverse collaborative cross mouse founder strains reveals diverse phenotype response and amelioration by quercetin treatment in 129S1/SvImJ … LE Griffin, L Essenmacher, KC Racine, L Iglesias-Carres, JS Tessem, ... The Journal of Nutritional Biochemistry 87, 108521, 2021 | 13 | 2021 |
James DeGregoriProfessor of Biochemistry and Molecular Genetics, University of Colorado SOMVerified email at ucdenver.edu
