Rebekah Bower
Rebekah Bower
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A second trigeminal CGRP receptor: function and expression of the AMY1 receptor
CS Walker, S Eftekhari, RL Bower, A Wilderman, PA Insel, L Edvinsson, ...
Annals of clinical and translational neurology 2 (6), 595-608, 2015
Amylin structure–function relationships and receptor pharmacology: implications for amylin mimetic drug development
RL Bower, DL Hay
British journal of pharmacology 173 (12), 1883-1898, 2016
Molecular studies of CGRP and the CGRP family of peptides in the central nervous system
ER Hendrikse, RL Bower, DL Hay, CS Walker
Cephalalgia 39 (3), 403-419, 2019
Molecular signature for receptor engagement in the metabolic peptide hormone amylin
RL Bower, L Yule, TA Rees, G Deganutti, ER Hendrikse, PWR Harris, ...
ACS Pharmacology & Translational Science 1 (1), 32-49, 2018
Mapping the calcitonin receptor in human brain stem
RL Bower, S Eftekhari, HJ Waldvogel, RLM Faull, J Tajti, L Edvinsson, ...
American Journal of Physiology-Regulatory, Integrative and Comparativeá…, 2016
Amyloidogenicity, cytotoxicity, and receptor activity of bovine amylin: implications for xenobiotic transplantation and the design of nontoxic amylin variants
R Akter, RL Bower, A Abedini, AM Schmidt, DL Hay, DP Raleigh
ACS chemical biology 13 (9), 2747-2757, 2018
Pharmacological characterisation of mouse calcitonin and calcitonin receptor‐like receptors reveals differences compared with human receptors
ML Garelja, RL Bower, MA Brimble, S Chand, PWR Harris, ...
British Journal of Pharmacology 179 (3), 416-434, 2022
Identification of small-molecule positive modulators of calcitonin-like receptor-based receptors
ER Hendrikse, LP Liew, RL Bower, M Bonnet, MA Jamaluddin, N Prodan, ...
ACS Pharmacology & Translational Science 3 (2), 305-320, 2020
Synthesis and amylin receptor activity of glycomimetics of pramlintide using click chemistry
LR Yule, RL Bower, H Kaur, R Kowalczyk, DL Hay, MA Brimble
Organic & Biomolecular Chemistry 14 (23), 5238-5245, 2016
The effect of metformin in EML4-ALK+ lung cancer alone and in combination with crizotinib in cell and rodent models
AR Bland, N Shrestha, RL Bower, RJ Rosengren, JC Ashton
Biochemical Pharmacology 183, 114345, 2021
Cytotoxicity of curcumin derivatives in ALK positive non-small cell lung cancer
AR Bland, RL Bower, M Nimick, BC Hawkins, RJ Rosengren, JC Ashton
European Journal of Pharmacology 865, 172749, 2019
Lipidated Calcitonin gene-related peptide (CGRP) peptide antagonists retain CGRP receptor activity and attenuate CGRP action in vivo
A Jamaluddin, CL Chuang, ET Williams, A Siow, SH Yang, PWR Harris, ...
Frontiers in Pharmacology, 570, 2022
Analysis of amylin consensus sequences suggests that human amylin is not optimized to minimize amyloid formation and provides clues to factors that modulate amyloidogenicity
D Noh, RL Bower, DL Hay, A Zhyvoloup, DP Raleigh
ACS chemical biology 15 (6), 1408-1416, 2020
The Synthesis of (▒)‐Oxyisocyclointegrin
RJ Smith, RL Bower, SA Ferguson, RJ Rosengren, GM Cook, ...
European Journal of Organic Chemistry 2019 (7), 1571-1573, 2019
Synthesis and Biological Evaluation of (−) and (+)‐Spiroleucettadine and Analogues
MP Badart, EM Barnes, AP Cording, SCL Gilmer, ID Billinghurst, ...
ChemMedChem 16 (8), 1308-1315, 2021
Inhibition of Mitogen-Activated Protein Kinase Kinase Alone and in Combination with Anaplastic Lymphoma Kinase (ALK) Inhibition Suppresses Tumor Growth in a Mouse Model of ALKá…
N Shrestha, AR Bland, RL Bower, RJ Rosengren, JC Ashton
Journal of Pharmacology and Experimental Therapeutics 374 (1), 134-140, 2020
Molecular determinants of amylin receptor agonism
R Bower
PhD Thesis-University of Auckland, 2017
Function and expression of two calcitonin gene-related peptide receptors within the sensory trigeminal system
D Hay, S Eftekhari, R Bower, A Wilderman, P Insel, L Edvinsson, ...
CEPHALALGIA 35, 5-6, 2015
From barnyard to bedside: using interspecies variants to inform the rational design of novel analogs of islet amyloid polypeptide
MET Miller, R Akter, A Zhyvoloup, RL Bower, A Abedini, DL Hay, ...
Biophysical Journal 121 (3), 46a, 2022
Repurposing the hypoglycemic agent, metformin, for targeted lung cancer
AR Bland, N Shrestha, RL Bower, RJ Rosengren, JC Ashton
New Zealand Medical Association, 2021
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