| Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13181* | 2021 |
| Molecular ordering of the caspase activation cascade initiated by the cytotoxic T lymphocyte/natural killer (CTL/NK) protease granzyme B C Adrain, BM Murphy, SJ Martin Journal of Biological Chemistry 280 (6), 4663-4673, 2005 | 232 | 2005 |
| The Apoptosome Pathway to Caspase Activation in Primary Human Neutrophils Exhibits Dramatically Reduced Requirements for Cytochrome c BM Murphy, AJ O'Neill, C Adrain, RWG Watson, SJ Martin The Journal of experimental medicine 197 (5), 625-632, 2003 | 148 | 2003 |
| Smac/Diablo antagonizes ubiquitin ligase activity of inhibitor of apoptosis proteins EM Creagh, BM Murphy, PJ Duriez, CS Duckett, SJ Martin Journal of Biological Chemistry 279 (26), 26906-26914, 2004 | 123 | 2004 |
| Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway CG Concannon, BF Koehler, C Reimertz, BM Murphy, C Bonner, ... Oncogene 26 (12), 1681-1692, 2007 | 120 | 2007 |
| Partial cleavage of RasGAP by caspases is required for cell survival in mild stress conditions JY Yang, D Michod, J Walicki, BM Murphy, S Kasibhatla, SJ Martin, ... Molecular and cellular biology 24 (23), 10425-10436, 2004 | 107 | 2004 |
| Targeting the anti-apoptotic Bcl-2 family members for the treatment of cancer B Weyhenmeyer, AC Murphy, JHM Prehn, BM Murphy Experimental oncology, 2012 | 104 | 2012 |
| Modulators of neuronal cell death in epilepsy DC Henshall, BM Murphy Current opinion in pharmacology 8 (1), 75-81, 2008 | 86 | 2008 |
| Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma T Engel, BM Murphy, S Hatazaki, EM Jimenez-Mateos, CG Concannon, ... The FASEB Journal 24 (3), 853, 2010 | 69 | 2010 |
| Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance … S Thompson, AN Pearson, MD Ashley, V Jessick, BM Murphy, P Gafken, ... Journal of Biological Chemistry 286 (22), 19331-19339, 2011 | 66 | 2011 |
| Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach ÁC Murphy, B Weyhenmeyer, J Schmid, SM Kilbride, M Rehm, HJ Huber, ... Cell death & disease 4 (5), e629-e629, 2013 | 62 | 2013 |
| Evidence of tumor necrosis factor receptor 1 signaling in human temporal lobe epilepsy A Yamamoto, CK Schindler, BM Murphy, C Bellver-Estelles, NK So, ... Experimental neurology 202 (2), 410-420, 2006 | 61 | 2006 |
| Bcl-w protects hippocampus during experimental status epilepticus B Murphy, M Dunleavy, S Shinoda, C Schindler, R Meller, ... The American journal of pathology 171 (4), 1258-1268, 2007 | 60 | 2007 |
| Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis ÁC Murphy, B Weyhenmeyer, J Noonan, SM Kilbride, S Schimansky, ... Apoptosis 19, 629-642, 2014 | 54 | 2014 |
| Contrasting patterns of Bim induction and neuroprotection in Bim-deficient mice between hippocampus and neocortex after status epilepticus BM Murphy, T Engel, A Paucard, S Hatazaki, G Mouri, K Tanaka, LP Tuffy, ... Cell Death & Differentiation 17 (3), 459-468, 2010 | 51 | 2010 |
| Elevated p53 and lower MDM2 expression in hippocampus from patients with intractable temporal lobe epilepsy T Engel, BM Murphy, CK Schindler, DC Henshall Epilepsy research 77 (2-3), 151-156, 2007 | 44 | 2007 |
| Depletion of 14‐3‐3 zeta elicits endoplasmic reticulum stress and cell death, and increases vulnerability to kainate‐induced injury in mouse hippocampal cultures N Murphy, HP Bonner, MW Ward, BM Murphy, JHM Prehn, DC Henshall Journal of neurochemistry 106 (2), 978-988, 2008 | 43 | 2008 |
| New hints towards a precision medicine strategy for IDH wild-type glioblastoma K White, K Connor, J Clerkin, BM Murphy, M Salvucci, AC O'Farrell, ... Annals of Oncology 31 (12), 1679-1692, 2020 | 42 | 2020 |
| Interchain proteolysis, in the absence of a dimerization stimulus, can initiate apoptosis-associated caspase-8 activation BM Murphy, EM Creagh, SJ Martin Journal of Biological Chemistry 279 (35), 36916-36922, 2004 | 40 | 2004 |
| Cyclin-dependent kinase inhibitors in brain cancer: Current state and future directions V Juric, B Murphy Cancer Drug Resistance 3 (1), 48, 2020 | 37 | 2020 |
Jochen H M PrehnRoyal College of Surgeons in Ireland University of Medicine and Health SciencesVerified email at rcsi.ie
