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Thanh N Nguyen
Thanh N Nguyen
Verified email at wehi.edu.au
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Year
Atg8 family LC3/GABARAP proteins are crucial for autophagosome–lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation
TN Nguyen, BS Padman, J Usher, V Oorschot, G Ramm, M Lazarou
Journal of Cell Biology 215 (6), 857-874, 2016
5872016
Deciphering the molecular signals of PINK1/Parkin mitophagy
TN Nguyen, BS Padman, M Lazarou
Trends in cell biology 26 (10), 733-744, 2016
5562016
LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy
BS Padman, TN Nguyen, L Uoselis, M Skulsuppaisarn, LK Nguyen, ...
Nature communications 10 (1), 408, 2019
1872019
Bax targets mitochondria by distinct mechanisms before or during apoptotic cell death: a requirement for VDAC2 or Bak for efficient Bax apoptotic function
SB Ma, TN Nguyen, I Tan, R Ninnis, S Iyer, DA Stroud, M Menard, ...
Cell Death & Differentiation 21 (12), 1925-1935, 2014
1272014
Gene knockout using transcription activator-like effector nucleases (TALENs) reveals that human NDUFA9 protein is essential for stabilizing the junction between membrane and …
DA Stroud, LE Formosa, XW Wijeyeratne, TN Nguyen, MT Ryan
Journal of Biological Chemistry 288 (3), 1685-1690, 2013
972013
The porin VDAC2 is the mitochondrial platform for Bax retrotranslocation
J Lauterwasser, F Todt, RM Zerbes, TN Nguyen, W Craigen, M Lazarou, ...
Scientific reports 6 (1), 32994, 2016
842016
A human apolipoprotein L with detergent-like activity kills intracellular pathogens
RG Gaudet, S Zhu, A Halder, BH Kim, CJ Bradfield, S Huang, D Xu, ...
Science 373 (6552), eabf8113, 2021
582021
ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system
TN Nguyen, BS Padman, S Zellner, G Khuu, L Uoselis, WK Lam, ...
Molecular cell 81 (9), 2013-2030. e9, 2021
542021
Autophagosome formation and cargo sequestration in the absence of LC3/GABARAPs
BS Padman, TN Nguyen, M Lazarou
Autophagy 13 (4), 772-774, 2017
412017
Unconventional initiation of PINK1/Parkin mitophagy by Optineurin
TN Nguyen, J Sawa-Makarska, G Khuu, WK Lam, E Adriaenssens, ...
Molecular cell 83 (10), 1693-1709. e9, 2023
252023
Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation
X Ren, TN Nguyen, WK Lam, CZ Buffalo, M Lazarou, AL Yokom, ...
Science advances 9 (7), eadg2997, 2023
212023
Mitochondrial degradation: Mitophagy and beyond
L Uoselis, TN Nguyen, M Lazarou
Molecular cell, 2023
192023
Insights on autophagosome–lysosome tethering from structural and biochemical characterization of human autophagy factor EPG5
MLCKY Sung-Eun Nam, Yiu Wing Sunny Cheung, Thanh Ngoc Nguyen, Michael Gong ...
Communications Biology, 2021
162021
ATG8ylation of proteins: A way to cope with cell stress?
JM Carosi, TN Nguyen, M Lazarou, S Kumar, TJ Sargeant
Journal of Cell Biology 220 (11), 2021
112021
A unifying model for the role of the ATG8 system in autophagy
TN Nguyen, M Lazarou
Journal of Cell Science 135 (11), jcs258997, 2022
102022
ATG4s: above and beyond the Atg8-family protein lipidation system
TN Nguyen, BS Padman, M Lazarou
Autophagy 17 (9), 2648-2650, 2021
32021
Plant mitophagy: Beware of Friendly or you might get eaten
TN Nguyen, M Lazarou
Current Biology 31 (9), R457-R458, 2021
32021
Rebellious autophagy proteins bypass ATG8 lipidation, taking their own path to autophagic degradation
TN Nguyen, M Lazarou
The EMBO Journal 39 (24), e106990, 2020
32020
Exposure of the inner mitochondrial membrane triggers apoptotic mitophagy
TL Saunders, SP Windley, G Gervinskas, KR Balka, C Rowe, R Lane, ...
Cell Death & Differentiation, 1-13, 2024
2024
Interaction of PINK1 with nucleotides and kinetin
ZY Gan, S Callegari, TN Nguyen, NS Kirk, A Leis, M Lazarou, G Dewson, ...
Science Advances 10 (3), eadj7408, 2024
2024
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