CRISPR-Cas9 knockin mice for genome editing and cancer modeling RJ Platt, S Chen, Y Zhou, MJ Yim, L Swiech, HR Kempton, JE Dahlman, ... Cell 159 (2), 440-455, 2014 | 2078 | 2014 |
Treating metastatic cancer with nanotechnology A Schroeder, DA Heller, MM Winslow, JE Dahlman, GW Pratt, R Langer, ... Nature Reviews Cancer 12 (1), 39-50, 2012 | 1287 | 2012 |
Emerging frontiers in drug delivery MW Tibbitt, JE Dahlman, R Langer Journal of the American Chemical Society 138 (3), 704-717, 2016 | 968 | 2016 |
Drug delivery systems for RNA therapeutics K Paunovska, D Loughrey, JE Dahlman Nature Reviews Genetics 23 (5), 265-280, 2022 | 688 | 2022 |
In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight JE Dahlman, C Barnes, OF Khan, A Thiriot, S Jhunjunwala, TE Shaw, ... Nature nanotechnology 9 (8), 648-655, 2014 | 681 | 2014 |
Proliferation and recruitment contribute to myocardial macrophage expansion in chronic heart failure HB Sager, M Hulsmans, KJ Lavine, MB Moreira, T Heidt, G Courties, ... Circulation research 119 (7), 853-864, 2016 | 409 | 2016 |
Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease JE Dahlman, OO Abudayyeh, J Joung, JS Gootenberg, F Zhang, ... Nature biotechnology 33 (11), 1159-1161, 2015 | 309 | 2015 |
Small RNA combination therapy for lung cancer W Xue, JE Dahlman, T Tammela, OF Khan, S Sood, A Dave, W Cai, ... Proceedings of the National Academy of Sciences 111 (34), E3553-E3561, 2014 | 269 | 2014 |
High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing CD Sago, MP Lokugamage, K Paunovska, DA Vanover, CM Monaco, ... Proceedings of the National Academy of Sciences 115 (42), E9944-E9952, 2018 | 266 | 2018 |
Silencing or stimulation? siRNA delivery and the immune system KA Whitehead, JE Dahlman, RS Langer, DG Anderson Annual review of chemical and biomolecular engineering 2 (1), 77-96, 2011 | 262 | 2011 |
Optimization of lipid nanoparticles for the delivery of nebulized therapeutic mRNA to the lungs MP Lokugamage, D Vanover, J Beyersdorf, MZC Hatit, L Rotolo, ... Nature biomedical engineering 5 (9), 1059-1068, 2021 | 261 | 2021 |
Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics JE Dahlman, KJ Kauffman, Y Xing, TE Shaw, FF Mir, CC Dlott, R Langer, ... Proceedings of the National Academy of Sciences 114 (8), 2060-2065, 2017 | 254 | 2017 |
Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis PY Chen, L Qin, G Li, Z Wang, JE Dahlman, J Malagon-Lopez, S Gujja, ... Nature metabolism 1 (9), 912-926, 2019 | 235 | 2019 |
RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction HB Sager, P Dutta, JE Dahlman, M Hulsmans, G Courties, Y Sun, T Heidt, ... Science translational medicine 8 (342), 342ra80-342ra80, 2016 | 198 | 2016 |
A direct comparison of in vitro and in vivo nucleic acid delivery mediated by hundreds of nanoparticles reveals a weak correlation K Paunovska, CD Sago, CM Monaco, WH Hudson, MG Castro, ... Nano letters 18 (3), 2148-2157, 2018 | 196 | 2018 |
Nanoparticles containing oxidized cholesterol deliver mRNA to the liver microenvironment at clinically relevant doses K Paunovska, AJ Da Silva Sanchez, CD Sago, Z Gan, MP Lokugamage, ... Advanced materials 31 (14), 1807748, 2019 | 168 | 2019 |
Challenges in carrier‐mediated intracellular delivery: moving beyond endosomal barriers MP Stewart, A Lorenz, J Dahlman, G Sahay Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 8 (3 …, 2016 | 151 | 2016 |
Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature OF Khan, EW Zaia, S Jhunjhunwala, W Xue, W Cai, DS Yun, CM Barnes, ... Nano letters 15 (5), 3008-3016, 2015 | 138 | 2015 |
Genetic and hypoxic alterations of the micro RNA‐210‐ISCU 1/2 axis promote iron–sulfur deficiency and pulmonary hypertension K White, Y Lu, S Annis, AE Hale, BN Chau, JE Dahlman, C Hemann, ... EMBO molecular medicine 7 (6), 695-713, 2015 | 135 | 2015 |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using particle delivery components J Dahlman, RJ PLATT, DG Anderson, R Langer, F Zhang | 134 | 2015 |