| A genome-wide association study identifies novel risk loci for type 2 diabetes R Sladek, G Rocheleau, J Rung, C Dina, L Shen, D Serre, P Boutin, ... Nature 445 (7130), 881-885, 2007 | 3803 | 2007 |
| Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus P Vafiadis, ST Bennett, JA Todd, J Nadeau, R Grabs, CG Goodyer, ... Nature genetics 15 (3), 289-292, 1997 | 1043 | 1997 |
| Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations D Meyre, J Delplanque, JC Chèvre, C Lecoeur, S Lobbens, S Gallina, ... Nature genetics 41 (2), 157-159, 2009 | 783 | 2009 |
| Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease DN Cooper, M Krawczak, C Polychronakos, C Tyler-Smith, ... Human genetics 132, 1077-1130, 2013 | 754 | 2013 |
| A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene H Hakonarson, SFA Grant, JP Bradfield, L Marchand, CE Kim, ... Nature 448 (7153), 591-594, 2007 | 653 | 2007 |
| Guidelines for growth hormone and insulin-like growth factor-I treatment in children and adolescents: growth hormone deficiency, idiopathic short stature, and primary insulin … A Grimberg, SA DiVall, C Polychronakos, DB Allen, LE Cohen, JB Quintos, ... Hormone Research in Paediatrics 86 (6), 361-397, 2017 | 607 | 2017 |
| Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia J Rung, S Cauchi, A Albrechtsen, L Shen, G Rocheleau, ... Nature genetics 41 (10), 1110-1115, 2009 | 555 | 2009 |
| Parental genomic imprinting of the human IGF2 gene N Giannoukakis, C Deal, J Paquette, CG Goodyer, C Polychronakos Nature genetics 4 (1), 98-101, 1993 | 532 | 1993 |
| Utility of whole‐exome sequencing for those near the end of the diagnostic odyssey: time to address gaps in care SL Sawyer, T Hartley, DA Dyment, CL Beaulieu, J Schwartzentruber, ... Clinical genetics 89 (3), 275-284, 2016 | 448 | 2016 |
| Rfx6 directs islet formation and insulin production in mice and humans SB Smith, HQ Qu, N Taleb, NY Kishimoto, DW Scheel, Y Lu, AM Patch, ... Nature 463 (7282), 775-780, 2010 | 405 | 2010 |
| A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci JP Bradfield, HQ Qu, K Wang, H Zhang, PM Sleiman, CE Kim, FD Mentch, ... PLoS genetics 7 (9), e1002293, 2011 | 400 | 2011 |
| A common autoimmunity predisposing signal peptide variant of the cytotoxic T-lymphocyte antigen 4 results in inefficient glycosylation of the susceptibility allele S Anjos, A Nguyen, H Ounissi-Benkalha, MC Tessier, C Polychronakos Journal of Biological Chemistry 277 (48), 46478-46486, 2002 | 347 | 2002 |
| Insulin expression levels in the thymus modulate insulin-specific autoreactive T-cell tolerance: the mechanism by which the IDDM2 locus may predispose to diabetes AA Chentoufi, C Polychronakos Diabetes 51 (5), 1383-1390, 2002 | 312 | 2002 |
| Understanding type 1 diabetes through genetics: advances and prospects C Polychronakos, Q Li Nature Reviews Genetics 12 (11), 781-792, 2011 | 309 | 2011 |
| Effect of tamoxifen on serum insulinlike growth factor I levels in stage I breast cancer patients M Pollak, J Costantino, C Polychronakos, SA Blauer, H Guyda, ... JNCI: Journal of the National Cancer Institute 82 (21), 1693-1697, 1990 | 295 | 1990 |
| A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels N Bouatia-Naji, G Rocheleau, L Van Lommel, K Lemaire, F Schuit, ... Science 320 (5879), 1085-1088, 2008 | 294 | 2008 |
| Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases YR Li, J Li, SD Zhao, JP Bradfield, FD Mentch, SM Maggadottir, C Hou, ... Nature medicine 21 (9), 1018-1027, 2015 | 281 | 2015 |
| From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes Z Wei, K Wang, HQ Qu, H Zhang, J Bradfield, C Kim, E Frackleton, C Hou, ... PLoS genetics 5 (10), e1000678, 2009 | 274 | 2009 |
| An imprinted locus associated with transient neonatal diabetes mellitus RJ Gardner, DJG Mackay, AJ Mungall, C Polychronakos, R Siebert, ... Human molecular genetics 9 (4), 589-596, 2000 | 274 | 2000 |
| Functional polymorphism in the parental imprinting of the human IGF2R gene YQ Xu, CG Goodyer, C Deal, C Polychronakos Biochemical and biophysical research communications 197 (2), 747-754, 1993 | 268 | 1993 |
