A comprehensive, CRISPR-based functional analysis of essential genes in bacteria JM Peters, A Colavin, H Shi, TL Czarny, MH Larson, S Wong, JS Hawkins, ... Cell 165 (6), 1493-1506, 2016 | 723 | 2016 |
Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase MA Farha, TL Czarny, CL Myers, LJ Worrall, S French, DG Conrady, ... Proceedings of the National Academy of Sciences 112 (35), 11048-11053, 2015 | 112 | 2015 |
Antibiotics as probes of biological complexity SB Falconer, TL Czarny, ED Brown Nature chemical biology 7 (7), 415-423, 2011 | 78 | 2011 |
Discovery of an antivirulence compound that reverses β-lactam resistance in MRSA OM El-Halfawy, TL Czarny, RS Flannagan, J Day, JC Bozelli, RC Kuiack, ... Nature chemical biology 16 (2), 143-149, 2020 | 73 | 2020 |
Discovery of Novel Cell Wall-Active Compounds Using PywaC, a Sensitive Reporter of Cell Wall Stress, in the Model Gram-Positive Bacterium Bacillus subtilis TL Czarny, AL Perri, S French, ED Brown Antimicrobial agents and chemotherapy 58 (6), 3261-3269, 2014 | 52 | 2014 |
Laminar flow effects during laser-induced oxidative labeling for protein structural studies by mass spectrometry L Konermann, BB Stocks, T Czarny Analytical chemistry 82 (15), 6667-6674, 2010 | 28 | 2010 |
A small-molecule screening platform for the discovery of inhibitors of undecaprenyl diphosphate synthase TL Czarny, ED Brown ACS Infectious Diseases 2 (7), 489-499, 2016 | 21 | 2016 |
Membrane activity profiling of small molecule B. subtilis growth inhibitors utilizing novel duel-dye fluorescence assay S McAuley, A Huynh, TL Czarny, ED Brown, JR Nodwell MedChemComm 9 (3), 554-561, 2018 | 18 | 2018 |
Armeniaspirols inhibit the AAA+ proteases ClpXP and ClpYQ leading to cell division arrest in Gram-positive bacteria P Labana, MH Dornan, M Lafrenière, TL Czarny, ED Brown, JP Pezacki, ... Cell Chemical Biology 28 (12), 1703-1715. e11, 2021 | 12 | 2021 |
485 Marta E, Shiver AL, Whitehead EH, Weissman JS, Brown ED, Qi LS, Huang KC, Gross CA. 486 2016. A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in 487 … JM Peters, A Colavin, H Shi, TL Czarny, MH Larson, S Wong, JS Hawkins, ... Cell 165, 1493-1506, 0 | 11 | |
Effect of antagonists of adrenergic and cholinergic receptors on ion transport in the isolated rabbit caecum wall DI Kosik-Bogacka, B Banach, T Tyrakowski, T Czarny, L Jodko Polish journal of pharmacology 56 (3), 319-326, 2004 | 2 | 2004 |
Armeniaspirols inhibit the ATP-dependent proteases ClpYQ and ClpXP in Gram-positive bacteria, dysregulating the divisome P Labana, MH Dornan, M Lafrenière, TL Czarny, ED Brown, JP Pezacki, ... bioRxiv, 685669, 2019 | | 2019 |
UNCONVENTIONAL HIGH-THROUGHPUT SCREENING TECHNIQUES FOR THE DISCOVERY OF CELL WALL ANTIBIOTICS T Czarny | | 2016 |
Discovery of an antivirulence compound that reverses β-lactam resistance in MRSA M Omar, TL Czarny, RS Flannagan, J Day, JC Bozelli Jr, RC Kuiack, ... | | |