Recognition of unique carboxyl-terminal motifs by distinct PDZ domains Z Songyang, AS Fanning, C Fu, J Xu, SM Marfatia, AH Chishti, ... Science 275 (5296), 73-77, 1997 | 1799 | 1997 |
Immunology of COVID-19: current state of the science N Vabret, GJ Britton, C Gruber, S Hegde, J Kim, M Kuksin, R Levantovsky, ... Immunity 52 (6), 910-941, 2020 | 1703 | 2020 |
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR ζ chain AC Chan, M Iwashima, CW Turck, A Weiss Cell 71 (4), 649-662, 1992 | 1400 | 1992 |
Therapeutic antibodies for autoimmunity and inflammation AC Chan, PJ Carter Nature reviews immunology 10 (5), 301-316, 2010 | 1165 | 2010 |
Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases M Iwashima, BA Irving, NSC Van Oers, AC Chan, A Weiss Science 263 (5150), 1136-1139, 1994 | 954 | 1994 |
T cell receptor signaling precedes immunological synapse formation KH Lee, AD Holdorf, ML Dustin, AC Chan, PM Allen, AS Shaw Science 295 (5559), 1539-1542, 2002 | 925 | 2002 |
Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype C Kemper, AC Chan, JM Green, KA Brett, KM Murphy, JP Atkinson Nature 421 (6921), 388-392, 2003 | 726 | 2003 |
The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction AC Chan, DM Desai, A Weiss Annual review of immunology 12 (1), 555-592, 1994 | 716 | 1994 |
BLNK: a central linker protein in B cell activation C Fu, CW Turck, T Kurosaki, AC Chan Immunity 9 (1), 93-103, 1998 | 701 | 1998 |
Essential role for ZAP-70 in both positive and negative selection of thymocytes I Negishi, N Motoyama, K Nakayama, K Nakayama, S Senju, ... Nature 376 (6539), 435-438, 1995 | 662 | 1995 |
Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy Q Gong, Q Ou, S Ye, WP Lee, J Cornelius, L Diehl, WY Lin, Z Hu, Y Lu, ... The Journal of Immunology 174 (2), 817-826, 2005 | 631 | 2005 |
Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase ME Elder, D Lin, J Clever, AC Chan, TJ Hope, A Weiss, TG Parslow Science 264 (5165), 1596-1599, 1994 | 606 | 1994 |
ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency AC Chan, TA Kadlecek, ME Elder, AH Filipovich, WL Kuo, M Iwashima, ... Science 264 (5165), 1599-1601, 1994 | 575 | 1994 |
A specificity map for the PDZ domain family R Tonikian, Y Zhang, SL Sazinsky, B Currell, JH Yeh, B Reva, HA Held, ... PLoS biology 6 (9), e239, 2008 | 564 | 2008 |
The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein. AC Chan, BA Irving, JD Fraser, A Weiss Proceedings of the National Academy of Sciences 88 (20), 9166-9170, 1991 | 558 | 1991 |
A biosynthetic pathway for anandamide J Liu, L Wang, J Harvey-White, D Osei-Hyiaman, R Razdan, Q Gong, ... Proceedings of the National Academy of Sciences 103 (36), 13345-13350, 2006 | 553 | 2006 |
Activation of ZAP‐70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function. AC Chan, M Dalton, R Johnson, GH Kong, T Wang, R Thoma, T Kurosaki The EMBO journal 14 (11), 2499-2508, 1995 | 484 | 1995 |
Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function JB Wardenburg, C Fu, JK Jackman, H Flotow, SE Wilkinson, DH Williams, ... Journal of Biological Chemistry 271 (33), 19641-19644, 1996 | 483 | 1996 |
PEST domain-enriched tyrosine phosphatase (PEP) regulation of effector/memory T cells K Hasegawa, F Martin, G Huang, D Tumas, L Diehl, AC Chan Science 303 (5658), 685-689, 2004 | 472 | 2004 |
Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data AR Abbas, D Baldwin, Y Ma, W Ouyang, A Gurney, F Martin, S Fong, ... Genes & Immunity 6 (4), 319-331, 2005 | 470 | 2005 |