| Live encapsulated porcine islets from a type 1 diabetic patient 9.5 yr after xenotransplantation RB Elliott, L Escobar, PLJ Tan, M Muzina, S Zwain, C Buchanan Xenotransplantation 14 (2), 157-161, 2007 | 478 | 2007 |
| The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019 KB Tran, JJ Lang, K Compton, R Xu, AR Acheson, HJ Henrikson, ... The Lancet 400 (10352), 563-591, 2022 | 389 | 2022 |
| Preptin derived from proinsulin-like growth factor II (proIGF-II) is secreted from pancreatic islet β-cells and enhances insulin secretion CM BUCHANAN, ARJ PHILLIPS, GJS COOPER Biochemical Journal 360 (2), 431-439, 2001 | 200 | 2001 |
| A brief relaxation intervention reduces stress and improves surgical wound healing response: a randomised trial E Broadbent, A Kahokehr, RJ Booth, J Thomas, JA Windsor, ... Brain, behavior, and immunity 26 (2), 212-217, 2012 | 189 | 2012 |
| A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell types S Jamieson, JU Flanagan, S Kolekar, C Buchanan, JD Kendall, WJ Lee, ... Biochemical Journal 438 (1), 53-62, 2011 | 176 | 2011 |
| Preptin, another peptide product of the pancreatic β-cell, is osteogenic in vitro and in vivo J Cornish, KE Callon, U Bava, M Watson, X Xu, JM Lin, VA Chan, AB Grey, ... American Journal of Physiology-Endocrinology and Metabolism 292 (1), E117-E122, 2007 | 131 | 2007 |
| Synthesis and biological evaluation of novel analogues of the pan class I phosphatidylinositol 3-kinase (PI3K) inhibitor 2-(difluoromethyl)-1-[4, 6-di (4-morpholinyl)-1, 3, 5 … GW Rewcastle, SA Gamage, JU Flanagan, R Frederick, WA Denny, ... Journal of medicinal chemistry 54 (20), 7105-7126, 2011 | 118 | 2011 |
| The chaperone proteins HSP70, HSP40/DnaJ and GRP78/BiP suppress misfolding and formation of β-sheet-containing aggregates by human amylin: a potential role for defective … V Chien, JF Aitken, S Zhang, CM Buchanan, A Hickey, T Brittain, ... Biochemical Journal 432 (1), 113-121, 2010 | 60 | 2010 |
| Proteins associated with immunopurified granules from a model pancreatic islet β-cell system: proteomic snapshot of an endocrine secretory granule AJR Hickey, JWI Bradley, GL Skea, MJ Middleditch, CM Buchanan, ... Journal of proteome research 8 (1), 178-186, 2009 | 56 | 2009 |
| The proteome of rodent mesenteric lymph A Mittal, M Middleditch, K Ruggiero, CM Buchanan, M Jullig, B Loveday, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 295 (5 …, 2008 | 44 | 2008 |
| DMXAA (Vadimezan, ASA404) is a multi-kinase inhibitor targeting VEGFR2 in particular CM Buchanan, JH Shih, JW Astin, GW Rewcastle, JU Flanagan, ... Clinical Science 122 (10), 449-465, 2012 | 41 | 2012 |
| Discovery of pyrazolo [1, 5-a] pyridines as p110α-selective PI3 kinase inhibitors JD Kendall, PD O’Connor, AJ Marshall, R Frédérick, ES Marshall, CL Lill, ... Bioorganic & medicinal chemistry 20 (1), 69-85, 2012 | 41 | 2012 |
| Novel pyrazolo [1, 5-a] pyridines as p110α-selective PI3 kinase inhibitors: Exploring the benzenesulfonohydrazide SAR JD Kendall, AC Giddens, KY Tsang, R Frédérick, ES Marshall, R Singh, ... Bioorganic & medicinal chemistry 20 (1), 58-68, 2012 | 40 | 2012 |
| Synthesis of Functionalized Pyrazolo [1, 5-a] pyridines:[3+ 2] Cycloaddition of N-Aminopyridines and α, β-Unsaturated Carbonyl Compounds/Alkenes at Room Temperature C Ravi, S Samanta, DC Mohan, NNK Reddy, S Adimurthy Synthesis 49 (11), 2513-2522, 2017 | 31 | 2017 |
| Enzyme activity effects of N-terminal His-tag attached to catalytic sub-unit of phosphoinositide-3-kinase JMJ Dickson, WJ Lee, PR Shepherd, CM Buchanan Bioscience reports 33 (6), e00079, 2013 | 31 | 2013 |
| Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance KG Mountjoy, A Caron, K Hubbard, A Shome, AC Grey, B Sun, S Bould, ... Molecular metabolism 9, 207-216, 2018 | 26 | 2018 |
| Preptin analogues: chemical synthesis, secondary structure and biological studies CM Buchanan, Z Peng, A Cefre, V Sarojini Chemical Biology & Drug Design 82 (4), 429-437, 2013 | 26 | 2013 |
| Direct visualisation of peptide hormones in cultured pancreatic islet alpha‐and beta‐cells by intact‐cell mass spectrometry CM Buchanan, AS Malik, GJS Cooper Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2007 | 24 | 2007 |
| Synthesis and biological evaluation of novel phosphatidylinositol 3-kinase inhibitors: Solubilized 4-substituted benzimidazole analogs of 2-(difluoromethyl)-1-[4, 6-di (4 … GW Rewcastle, SA Gamage, JU Flanagan, JD Kendall, WA Denny, ... European Journal of Medicinal Chemistry 64, 137-147, 2013 | 23 | 2013 |
| For better or worse: the potential for dose limiting the on-target toxicity of PI 3-kinase inhibitors CM Buchanan, KL Lee, PR Shepherd Biomolecules 9 (9), 402, 2019 | 22 | 2019 |
