| Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins. KM Pan, M Baldwin, J Nguyen, M Gasset, ANA Serban, D Groth, ... Proceedings of the National Academy of Sciences 90 (23), 10962-10966, 1993 | 3165 | 1993 |
| Eight prion strains have PrPSc molecules with different conformations J Safar, H Wille, V Itri, D Groth, H Serban, M Torchia, FE Cohen, ... Nature medicine 4 (10), 1157-1165, 1998 | 1527 | 1998 |
| An evolutionary trace method defines binding surfaces common to protein families O Lichtarge, HR Bourne, FE Cohen Journal of molecular biology 257 (2), 342-358, 1996 | 1484 | 1996 |
| Synthetic mammalian prions G Legname, IV Baskakov, HOB Nguyen, D Riesner, FE Cohen, ... Science 305 (5684), 673-676, 2004 | 1300 | 2004 |
| Prion protein biology SB Prusiner, MR Scott, SJ DeArmond, FE Cohen cell 93 (3), 337-348, 1998 | 1279 | 1998 |
| Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein GC Telling, M Scott, J Mastrianni, R Gabizon, M Torchia, FE Cohen, ... Cell 83 (1), 79-90, 1995 | 1124 | 1995 |
| Bayesian statistical analysis of protein side‐chain rotamer preferences RL Dunbrack Jr, FE Cohen Protein science 6 (8), 1661-1681, 1997 | 1054 | 1997 |
| Therapeutic approaches to protein-misfolding diseases FE Cohen, JW Kelly Nature 426 (6968), 905-909, 2003 | 1018 | 2003 |
| Improvements in protein secondary structure prediction by an enhanced neural network DG Kneller, FE Cohen, R Langridge Journal of molecular biology 214 (1), 171-182, 1990 | 938 | 1990 |
| Structure of the recombinant full-length hamster prion protein PrP (29–231): the N terminus is highly flexible DG Donne, JH Viles, D Groth, I Mehlhorn, TL James, FE Cohen, ... Proceedings of the National Academy of Sciences 94 (25), 13452-13457, 1997 | 876 | 1997 |
| Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease C Korth, BCH May, FE Cohen, SB Prusiner Proceedings of the National Academy of Sciences 98 (17), 9836-9841, 2001 | 864 | 2001 |
| Pathologic conformations of prion proteins FE Cohen, SB Prusiner Annual review of biochemistry 67 (1), 793-819, 1998 | 736 | 1998 |
| Structural clues to prion replication FE Cohen, KM Pan, Z Huang, M Baldwin, RJ Fletterick, SB Prusiner Science 264 (5158), 530-531, 1994 | 721 | 1994 |
| Copper binding to the prion protein: structural implications of four identical cooperative binding sites JH Viles, FE Cohen, SB Prusiner, DB Goodin, PE Wright, HJ Dyson Proceedings of the National Academy of Sciences 96 (5), 2042-2047, 1999 | 714 | 1999 |
| Evidence for assembly of prions with left-handed β-helices into trimers C Govaerts, H Wille, SB Prusiner, FE Cohen Proceedings of the National Academy of Sciences 101 (22), 8342-8347, 2004 | 713 | 2004 |
| Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation K Kaneko, L Zulianello, M Scott, CM Cooper, AC Wallace, TL James, ... Proceedings of the national academy of sciences 94 (19), 10069-10074, 1997 | 703 | 1997 |
| Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel RC Moore, IY Lee, GL Silverman, PM Harrison, R Strome, C Heinrich, ... Journal of molecular biology 292 (4), 797-817, 1999 | 698 | 1999 |
| Prediction of protein side-chain rotamers from a backbone-dependent rotamer library: a new homology modeling tool MJ Bower, FE Cohen, RL Dunbrack Jr Journal of molecular biology 267 (5), 1268-1282, 1997 | 696 | 1997 |
| Prion protein selectively binds copper (II) ions J Stöckel, J Safar, AC Wallace, FE Cohen, SB Prusiner Biochemistry 37 (20), 7185-7193, 1998 | 671 | 1998 |
| Sequence-specific polypeptoids: A diverse family of heteropolymers with stable secondary structure K Kirshenbaum, AE Barron, RA Goldsmith, P Armand, EK Bradley, ... Proceedings of the National Academy of Sciences 95 (8), 4303-4308, 1998 | 614 | 1998 |
