Cationic nanoparticles induce nanoscale disruption in living cell plasma membranes J Chen, JA Hessler, K Putchakayala, BK Panama, DP Khan, S Hong, ... The journal of physical chemistry B 113 (32), 11179-11185, 2009 | 256 | 2009 |
A quantitative assessment of nanoparticle− ligand distributions: implications for targeted drug and imaging delivery in dendrimer conjugates DG Mullen, M Fang, A Desai, JR Baker Jr, BG Orr, MM Banaszak Holl Acs Nano 4 (2), 657-670, 2010 | 175 | 2010 |
Cationic poly (amidoamine) dendrimer induces lysosomal apoptotic pathway at therapeutically relevant concentrations TP Thomas, I Majoros, A Kotlyar, D Mullen, MM Banaszak Holl, ... Biomacromolecules 10 (12), 3207-3214, 2009 | 121 | 2009 |
Solid-state NMR reveals the hydrophobic-core location of poly (amidoamine) dendrimers in biomembranes PES Smith, JR Brender, UHN Dürr, J Xu, DG Mullen, MM Banaszak Holl, ... Journal of the American Chemical Society 132 (23), 8087-8097, 2010 | 119 | 2010 |
Stoichiometry and structure of poly (amidoamine) dendrimer− lipid complexes CV Kelly, MG Liroff, LD Triplett, PR Leroueil, DG Mullen, JM Wallace, ... Acs Nano 3 (7), 1886-1896, 2009 | 99 | 2009 |
Heterogeneous ligand–nanoparticle distributions: A major obstacle to scientific understanding and commercial translation DG Mullen, MM Banaszak Holl Accounts of chemical research 44 (11), 1135-1145, 2011 | 90 | 2011 |
The Role of Ganglioside GM1 in Cellular Internalization Mechanisms of Poly(amidoamine) Dendrimers S Hong, R Rattan, IJ Majoros, DG Mullen, JL Peters, X Shi, AU Bielinska, ... Bioconjugate chemistry 20 (8), 1503-1513, 2009 | 89 | 2009 |
Best practices for purification and characterization of PAMAM dendrimer DG Mullen, A Desai, MA van Dongen, M Barash, JR Baker Jr, ... Macromolecules 45 (12), 5316-5320, 2012 | 70 | 2012 |
The implications of stochastic synthesis for the conjugation of functional groups to nanoparticles DG Mullen, AM Desai, JN Waddell, X Cheng, CV Kelly, DQ McNerny, ... Bioconjugate chemistry 19 (9), 1748-1752, 2008 | 67 | 2008 |
The mechanism of polyplex internalization into cells: testing the GM1/caveolin-1 lipid raft mediated endocytosis pathway R Qi, DG Mullen, JR Baker Jr, MM Banaszak Holl Molecular pharmaceutics 7 (1), 267-279, 2010 | 51 | 2010 |
Polycation-induced cell membrane permeability does not enhance cellular uptake or expression efficiency of delivered DNA LE Prevette, DG Mullen, MM Banaszak Holl Molecular pharmaceutics 7 (3), 870-883, 2010 | 48 | 2010 |
Interactions of poly (amidoamine) dendrimers with Survanta lung surfactant: the importance of lipid domains B Erickson, SC DiMaggio, DG Mullen, CV Kelly, PR Leroueil, SA Berry, ... Langmuir 24 (19), 11003-11008, 2008 | 46 | 2008 |
Design, synthesis, and biological functionality of a dendrimer-based modular drug delivery platform DG Mullen, DQ McNerny, A Desai, X Cheng, SC DiMaggio, A Kotlyar, ... Bioconjugate chemistry 22 (4), 679-689, 2011 | 45 | 2011 |
Isolation and characterization of dendrimer with precise numbers of functional groups DG Mullen, EL Borgmeier, AM Desai, MA Van Dongen, M Barash, ... Chemistry (Weinheim an der Bergstrasse, Germany) 16 (35), 10675, 2010 | 44 | 2010 |
RGD dendron bodies; synthetic avidity agents with defined and potentially interchangeable effector sites that can substitute for antibodies DQ McNerny, JF Kukowska-Latallo, DG Mullen, JM Wallace, AM Desai, ... Bioconjugate chemistry 20 (10), 1853-1859, 2009 | 42 | 2009 |
Acetonitrile shortage: Use of isopropanol as an alternative elution system for ultra/high performance liquid chromatography AM Desai, M Andreae, DG Mullen, MMB Holl, JR Baker Jr Analytical Methods 3 (1), 56-58, 2011 | 29 | 2011 |
Dendrimer based modular platforms JR Baker Jr, MMB Holl, XM Cheng, B Huang, D McNemy, DG Mullen, ... US Patent App. 12/645,081, 2010 | 23 | 2010 |
Effect of mass transport in the synthesis of partially acetylated dendrimer: implications for functional ligand− nanoparticle distributions DG Mullen, EL Borgmeier, M Fang, DQ McNerny, A Desai, JR Baker Jr, ... Macromolecules 43 (16), 6577-6587, 2010 | 16 | 2010 |
Origin of broad polydispersion in functionalized dendrimers and its effects on cancer-cell binding affinity JN Waddell, DG Mullen, BG Orr, MM Banaszak Holl, LM Sander Physical Review E—Statistical, Nonlinear, and Soft Matter Physics 82 (3 …, 2010 | 12 | 2010 |
Synthesis and isolation of dendrimer systems JR Baker Jr, MMB Holl, DG Mullen, BG Orr, A Desai, LM Sander, ... US Patent App. 13/392,421, 2012 | 9 | 2012 |