| Open source drug discovery with the malaria box compound collection for neglected diseases and beyond WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ... PLoS pathogens 12 (7), e1005763, 2016 | 294 | 2016 |
| Purine and pyrimidine pathways as targets in Plasmodium falciparum M Belen Cassera, Y Zhang, K Z Hazleton, V L Schramm Current topics in medicinal chemistry 11 (16), 2103-2115, 2011 | 168 | 2011 |
| The methylerythritol phosphate pathway is functionally active in all intraerythrocytic stages of Plasmodium falciparum MB Cassera, FC Gozzo, LD Fabio, EF Merino, HA Del Portillo, VJ Peres, ... Journal of Biological Chemistry 279 (50), 51749-51759, 2004 | 167 | 2004 |
| Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum NV Dharia, ABS Sidhu, MB Cassera, SJ Westenberger, SER Bopp, ... Genome biology 10, 1-13, 2009 | 165 | 2009 |
| Antiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the malaria box JD Bowman, EF Merino, CF Brooks, B Striepen, PR Carlier, MB Cassera Antimicrobial agents and chemotherapy 58 (2), 811-819, 2014 | 115 | 2014 |
| Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5′-methylthioadenosine phosphorylase I Basu, J Locker, MB Cassera, TJ Belbin, EF Merino, X Dong, I Hemeon, ... Journal of biological chemistry 286 (6), 4902-4911, 2011 | 97 | 2011 |
| Cyclic di-GMP modulates gene expression in Lyme disease spirochetes at the tick-mammal interface to promote spirochete survival during the blood meal and tick-to-mammal … MJ Caimano, S Dunham-Ems, AM Allard, MB Cassera, M Kenedy, ... Infection and immunity 83 (8), 3043-3060, 2015 | 80 | 2015 |
| Acyclic immucillin phosphonates: second-generation inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase KZ Hazleton, MC Ho, MB Cassera, K Clinch, DR Crump, I Rosario, ... Chemistry & biology 19 (6), 721-730, 2012 | 79 | 2012 |
| Plasmodium falciparum Parasites Are Killed by a Transition State Analogue of Purine Nucleoside Phosphorylase in a Primate Animal Model MB Cassera, KZ Hazleton, EF Merino, N Obaldia III, MC Ho, AS Murkin, ... PLoS One 6 (11), e26916, 2011 | 78 | 2011 |
| Metabolomic profiling reveals a finely tuned, starvation-induced metabolic switch in Trypanosoma cruzi epimastigotes MJ Barisón, LN Rapado, EF Merino, EMF Pral, BS Mantilla, L Marchese, ... Journal of Biological Chemistry 292 (21), 8964-8977, 2017 | 75 | 2017 |
| Nanomolar Antimalarial Agents against Chloroquine-Resistant Plasmodium falciparum from Medicinal Plants and Their Structure–Activity Relationships B Zhou, Y Wu, S Dalal, EF Merino, QF Liu, CH Xu, T Yuan, J Ding, ... Journal of natural products 80 (1), 96-107, 2017 | 74 | 2017 |
| Erythrocytic adenosine monophosphate as an alternative purine source in Plasmodium falciparum MB Cassera, KZ Hazleton, PM Riegelhaupt, EF Merino, M Luo, ... Journal of biological chemistry 283 (47), 32889-32899, 2008 | 68 | 2008 |
| Fortunoids A–C, Three Sesquiterpenoid Dimers with Different Carbon Skeletons from Chloranthus fortunei B Zhou, QF Liu, S Dalal, MB Cassera, JM Yue Organic letters 19 (3), 734-737, 2017 | 63 | 2017 |
| Euphorbesulins A–P, Structurally Diverse Diterpenoids from Euphorbia esula B Zhou, Y Wu, S Dalal, MB Cassera, JM Yue Journal of Natural Products 79 (8), 1952-1961, 2016 | 56 | 2016 |
| Antiproliferative and Antiplasmodial Dimeric Phloroglucinols from Mallotus oppositifolius from the Madagascar Dry Forest L Harinantenaina, JD Bowman, PJ Brodie, C Slebodnick, MW Callmander, ... Journal of natural products 76 (3), 388-393, 2013 | 55 | 2013 |
| Antimalarial 5,6-Dihydro-α-pyrones from Cryptocarya rigidifolia: Related Bicyclic Tetrahydro-α-Pyrones Are Artifacts1 Y Liu, LH Rakotondraibe, PJ Brodie, JD Wiley, MB Cassera, JS Miller, ... Journal of natural products 78 (6), 1330-1338, 2015 | 51 | 2015 |
| Isoprenoid precursor biosynthesis is the essential metabolic role of the apicoplast during gametocytogenesis in Plasmodium falciparum JD Wiley, EF Merino, PM Krai, KJ McLean, AK Tripathi, J Vega-Rodríguez, ... Eukaryotic cell 14 (2), 128-139, 2015 | 50 | 2015 |
| Effect of fosmidomycin on metabolic and transcript profiles of the methylerythritol phosphate pathway in Plasmodium falciparum MB Cassera, EF Merino, VJ Peres, EA Kimura, G Wunderlich, AM Katzin Memórias do Instituto Oswaldo Cruz 102, 377-384, 2007 | 46 | 2007 |
| Aphadilactones A–D, four diterpenoid dimers with DGAT inhibitory and antimalarial activities from a Meliaceae plant J Liu, XF He, GH Wang, EF Merino, SP Yang, RX Zhu, LS Gan, H Zhang, ... The Journal of Organic Chemistry 79 (2), 599-607, 2014 | 45 | 2014 |
| A solanesyl-diphosphate synthase localizes in glycosomes of Trypanosoma cruzi M Ferella, A Montalvetti, P Rohloff, K Miranda, J Fang, S Reina, ... Journal of biological chemistry 281 (51), 39339-39348, 2006 | 45 | 2006 |
