Paramjit S. Arora
Paramjit S. Arora
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Contemporary strategies for the stabilization of peptides in the α-helical conformation
LK Henchey, AL Jochim, PS Arora
Current opinion in chemical biology 12 (6), 692-697, 2008
An orthosteric inhibitor of the Ras-Sos interaction
A Patgiri, KK Yadav, PS Arora, D Bar-Sagi
Nature chemical biology 7 (9), 585-587, 2011
Assessing helical protein interfaces for inhibitor design
BN Bullock, AL Jochim, PS Arora
Journal of the American Chemical Society 133 (36), 14220-14223, 2011
A hydrogen bond surrogate approach for stabilization of short peptide sequences in α-helical conformation
A Patgiri, AL Jochim, PS Arora
Accounts of chemical research 41 (10), 1289-1300, 2008
A highly stable short α-helix constrained by a main-chain hydrogen-bond surrogate
RN Chapman, G Dimartino, PS Arora
Journal of the American Chemical Society 126 (39), 12252-12253, 2004
Nonpeptidic foldamers from amino acids: Synthesis and characterization of 1, 3-substituted triazole oligomers
NG Angelo, PS Arora
Journal of the American Chemical Society 127 (49), 17134-17135, 2005
Systematic analysis of helical protein interfaces reveals targets for synthetic inhibitors
AL Jochim, PS Arora
ACS chemical biology 5 (10), 919-923, 2010
Enhanced metabolic stability and protein‐binding properties of artificial α helices derived from a hydrogen‐bond surrogate: Application to Bcl‐xL
D Wang, W Liao, PS Arora
Angewandte Chemie International Edition 44 (40), 6525-6529, 2005
Systematic targeting of protein–protein interactions
AE Modell, SL Blosser, PS Arora
Trends in pharmacological sciences 37 (8), 702-713, 2016
Evaluation of biologically relevant short α-helices stabilized by a main-chain hydrogen-bond surrogate
D Wang, K Chen, JL Kulp, PS Arora
Journal of the American Chemical Society 128 (28), 9248-9256, 2006
Comparative ACE2 variation and primate COVID-19 risk
AD Melin, MC Janiak, F Marrone III, PS Arora, JP Higham
Communications biology 3 (1), 641, 2020
Inhibition of Hypoxia Inducible Factor 1 Transcription Coactivator Interaction by a Hydrogen Bond Surrogate α-Helix
LK Henchey, S Kushal, R Dubey, RN Chapman, BZ Olenyuk, PS Arora
Journal of the American Chemical Society 132 (3), 941-943, 2010
Novel RNA catalysts for the Michael reaction
G Sengle, A Eisenführ, PS Arora, JS Nowick, M Famulok
Chemistry & biology 8 (5), 459-473, 2001
Assessment of helical interfaces in protein–protein interactions
AL Jochim, PS Arora
Molecular BioSystems 5 (9), 924-926, 2009
Cellular uptake of N-methylpyrrole/N-methylimidazole polyamide-dye conjugates
JM Belitsky, SJ Leslie, PS Arora, TA Beerman, PB Dervan
Bioorganic & medicinal chemistry 10 (10), 3313-3318, 2002
Rational design of topographical helix mimics as potent inhibitors of protein–protein interactions
BB Lao, K Drew, DA Guarracino, TF Brewer, DW Heindel, R Bonneau, ...
Journal of the American Chemical Society 136 (22), 7877-7888, 2014
Design of artificial transcriptional activators with rigid poly-L-proline linkers
PS Arora, AZ Ansari, TP Best, M Ptashne, PB Dervan
Journal of the American Chemical Society 124 (44), 13067-13071, 2002
Solution-and solid-phase synthesis of triazole oligomers that display protein-like functionality
NG Angelo, PS Arora
The Journal of Organic Chemistry 72 (21), 7963-7967, 2007
Anatomy of β-strands at protein–protein interfaces
AM Watkins, PS Arora
ACS chemical biology 9 (8), 1747-1754, 2014
In vivo modulation of hypoxia-inducible signaling by topographical helix mimetics
BB Lao, I Grishagin, H Mesallati, TF Brewer, BZ Olenyuk, PS Arora
Proceedings of the National Academy of Sciences 111 (21), 7531-7536, 2014
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