Contemporary strategies for the stabilization of peptides in the α-helical conformation LK Henchey, AL Jochim, PS Arora Current opinion in chemical biology 12 (6), 692-697, 2008 | 362 | 2008 |
An orthosteric inhibitor of the Ras-Sos interaction A Patgiri, KK Yadav, PS Arora, D Bar-Sagi Nature chemical biology 7 (9), 585-587, 2011 | 355 | 2011 |
Assessing helical protein interfaces for inhibitor design BN Bullock, AL Jochim, PS Arora Journal of the American Chemical Society 133 (36), 14220-14223, 2011 | 352 | 2011 |
A hydrogen bond surrogate approach for stabilization of short peptide sequences in α-helical conformation A Patgiri, AL Jochim, PS Arora Accounts of chemical research 41 (10), 1289-1300, 2008 | 292 | 2008 |
A highly stable short α-helix constrained by a main-chain hydrogen-bond surrogate RN Chapman, G Dimartino, PS Arora Journal of the American Chemical Society 126 (39), 12252-12253, 2004 | 283 | 2004 |
Nonpeptidic foldamers from amino acids: Synthesis and characterization of 1, 3-substituted triazole oligomers NG Angelo, PS Arora Journal of the American Chemical Society 127 (49), 17134-17135, 2005 | 264 | 2005 |
Systematic analysis of helical protein interfaces reveals targets for synthetic inhibitors AL Jochim, PS Arora ACS chemical biology 5 (10), 919-923, 2010 | 213 | 2010 |
Systematic targeting of protein–protein interactions AE Modell, SL Blosser, PS Arora Trends in pharmacological sciences 37 (8), 702-713, 2016 | 195 | 2016 |
Enhanced metabolic stability and protein‐binding properties of artificial α helices derived from a hydrogen‐bond surrogate: Application to Bcl‐xL D Wang, W Liao, PS Arora Angewandte Chemie International Edition 44 (40), 6525-6529, 2005 | 193 | 2005 |
Evaluation of biologically relevant short α-helices stabilized by a main-chain hydrogen-bond surrogate D Wang, K Chen, JL Kulp, PS Arora Journal of the American Chemical Society 128 (28), 9248-9256, 2006 | 186 | 2006 |
Comparative ACE2 variation and primate COVID-19 risk AD Melin, MC Janiak, F Marrone III, PS Arora, JP Higham Communications biology 3 (1), 641, 2020 | 185 | 2020 |
Inhibition of Hypoxia Inducible Factor 1 Transcription Coactivator Interaction by a Hydrogen Bond Surrogate α-Helix LK Henchey, S Kushal, R Dubey, RN Chapman, BZ Olenyuk, PS Arora Journal of the American Chemical Society 132 (3), 941-943, 2010 | 173 | 2010 |
Novel RNA catalysts for the Michael reaction G Sengle, A Eisenführ, PS Arora, JS Nowick, M Famulok Chemistry & biology 8 (5), 459-473, 2001 | 170 | 2001 |
Assessment of helical interfaces in protein–protein interactions AL Jochim, PS Arora Molecular BioSystems 5 (9), 924-926, 2009 | 163 | 2009 |
Cellular uptake of N-methylpyrrole/N-methylimidazole polyamide-dye conjugates JM Belitsky, SJ Leslie, PS Arora, TA Beerman, PB Dervan Bioorganic & medicinal chemistry 10 (10), 3313-3318, 2002 | 159 | 2002 |
Rational design of topographical helix mimics as potent inhibitors of protein–protein interactions BB Lao, K Drew, DA Guarracino, TF Brewer, DW Heindel, R Bonneau, ... Journal of the American Chemical Society 136 (22), 7877-7888, 2014 | 145 | 2014 |
Solution-and solid-phase synthesis of triazole oligomers that display protein-like functionality NG Angelo, PS Arora The Journal of Organic Chemistry 72 (21), 7963-7967, 2007 | 132 | 2007 |
Design of artificial transcriptional activators with rigid poly-L-proline linkers PS Arora, AZ Ansari, TP Best, M Ptashne, PB Dervan Journal of the American Chemical Society 124 (44), 13067-13071, 2002 | 132 | 2002 |
In vivo modulation of hypoxia-inducible signaling by topographical helix mimetics BB Lao, I Grishagin, H Mesallati, TF Brewer, BZ Olenyuk, PS Arora Proceedings of the National Academy of Sciences 111 (21), 7531-7536, 2014 | 127 | 2014 |
Anatomy of β-strands at protein–protein interfaces AM Watkins, PS Arora ACS chemical biology 9 (8), 1747-1754, 2014 | 125 | 2014 |