Harshil Dhruv
Harshil Dhruv
Tolero Pharmaceuticals
Verified email at toleropharma.com
Cited by
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Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
VS Viswanathan, MJ Ryan, HD Dhruv, S Gill, OM Eichhoff, ...
Nature 547 (7664), 453-457, 2017
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
MJ Hangauer, VS Viswanathan, MJ Ryan, D Bole, JK Eaton, A Matov, ...
Nature 551 (7679), 247-250, 2017
Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks
JC Chen, MJ Alvarez, F Talos, H Dhruv, GE Rieckhof, A Iyer, KL Diefes, ...
Cell 159 (2), 402-414, 2014
MicroRNA‐328 is associated with (non‐small) cell lung cancer (NSCLC) brain metastasis and mediates NSCLC migration
S Arora, AR Ranade, NL Tran, S Nasser, S Sridhar, RL Korn, JTD Ross, ...
International journal of cancer 129 (11), 2621-2631, 2011
Intravenous delivery of camptothecin-loaded PLGA nanoparticles for the treatment of intracranial glioma
KT Householder, DM DiPerna, EP Chung, GM Wohlleb, HD Dhruv, ...
International journal of pharmaceutics 479 (2), 374-380, 2015
Evaluation of pre-analytical factors affecting plasma DNA analysis
H Markus, T Contente-Cuomo, M Farooq, WS Liang, MJ Borad, ...
Scientific reports 8 (1), 1-10, 2018
Reciprocal activation of transcription factors underlies the dichotomy between proliferation and invasion of glioma cells
HD Dhruv, WSMD Winslow, B Armstrong, S Tuncali, J Eschbacher, ...
PloS one 8 (8), e72134, 2013
Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma
RS McNeill, DA Canoutas, TJ Stuhlmiller, HD Dhruv, DM Irvin, RE Bash, ...
Neuro-oncology 19 (11), 1469-1480, 2017
TROY (TNFRSF19) promotes glioblastoma survival signaling and therapeutic resistance
JC Loftus, H Dhruv, S Tuncali, J Kloss, Z Yang, CA Schumacher, B Cao, ...
Molecular Cancer Research 11 (8), 865-874, 2013
Genomic and phenotypic characterization of a broad panel of patient-derived xenografts reflects the diversity of glioblastoma
RA Vaubel, S Tian, D Remonde, MA Schroeder, AC Mladek, GJ Kitange, ...
Clinical Cancer Research 26 (5), 1094-1104, 2020
Bioresponsive Copolymers of Poly(N-isopropylacrylamide) with Enzyme-Dependent Lower Critical Solution Temperatures
DJ Overstreet, HD Dhruv, BL Vernon
Biomacromolecules 11 (5), 1154-1159, 2010
Phase 0 trial of AZD1775 in first-recurrence glioblastoma patients
N Sanai, J Li, J Boerner, K Stark, J Wu, S Kim, A Derogatis, S Mehta, ...
Clinical Cancer Research 24 (16), 3820-3828, 2018
Integrated genomic analysis of survival outliers in glioblastoma
S Peng, H Dhruv, B Armstrong, B Salhia, C Legendre, J Kiefer, J Parks, ...
Neuro-oncology 19 (6), 833-844, 2017
A novel interaction between Pyk2 and MAP4K4 is integrated with glioma cell migration
JC Loftus, Z Yang, J Kloss, H Dhruv, NL Tran, DL Riggs
Journal of signal transduction 2013, 2013
Protein insertion and patterning of PEG bearing Langmuir monolayers
H Dhruv, R Pepalla, M Taveras, DW Britt
Biotechnology progress 22 (1), 150-155, 2006
Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells
A Roos, HD Dhruv, IT Mathews, LJ Inge, S Tuncali, LK Hartman, D Chow, ...
Oncotarget 8 (7), 12234, 2017
Structural basis and targeting of the interaction between fibroblast growth factor-inducible 14 and tumor necrosis factor-like weak inducer of apoptosis
H Dhruv, JC Loftus, P Narang, JL Petit, M Fameree, J Burton, G Tchegho, ...
Journal of Biological Chemistry 288 (45), 32261-32276, 2013
Differential response of glioma stem cells to arsenic trioxide therapy is regulated by MNK1 and mRNA translation
JB Bell, F Eckerdt, HD Dhruv, D Finlay, S Peng, S Kim, B Kroczynska, ...
Molecular Cancer Research 16 (1), 32-46, 2018
FN14 expression correlates with MET in NSCLC and promotes MET-driven cell invasion
TG Whitsett, SPF Ensign, HD Dhruv, LJ Inge, P Kurywchak, KK Wolf, ...
Clinical & experimental metastasis 31 (6), 613-623, 2014
EGFRvIII–Stat5 signaling enhances glioblastoma cell migration and survival
A Roos, HD Dhruv, S Peng, LJ Inge, S Tuncali, M Pineda, N Millard, ...
Molecular Cancer Research 16 (7), 1185-1195, 2018
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