| Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo’ E Lavezzo, E Franchin, C Ciavarella, G Cuomo-Dannenburg, L Barzon, ... Nature 584 (7821), 425-429, 2020 | 1016 | 2020 |
| Suppression of COVID-19 outbreak in the municipality of Vo’, Italy E Lavezzo, E Franchin, C Ciavarella, G Cuomo-Dannenburg, L Barzon, ... MedRxiv, 2020 | 378 | 2020 |
| The empirical antibiotic treatment of nosocomial spontaneous bacterial peritonitis: results of a randomized, controlled clinical trial S Piano, S Fasolato, F Salinas, A Romano, M Tonon, F Morando, ... Hepatology 63 (4), 1299-1309, 2016 | 278 | 2016 |
| Drug repurposing for viral infectious diseases: how far are we? B Mercorelli, G Palù, A Loregian Trends in microbiology 26 (10), 865-876, 2018 | 263 | 2018 |
| A point mutation in a herpesvirus polymerase determines neuropathogenicity LB Goodman, A Loregian, GA Perkins, J Nugent, EL Buckles, B Mercorelli, ... PLoS pathogens 3 (11), e160, 2007 | 249 | 2007 |
| Antiviral strategies against influenza virus: towards new therapeutic approaches A Loregian, B Mercorelli, G Nannetti, C Compagnin, G Palù Cellular and molecular life sciences 71, 3659-3683, 2014 | 175 | 2014 |
| Disruption of protein–protein interactions: towards new targets for chemotherapy A Loregian, G Palù Journal of cellular physiology 204 (3), 750-762, 2005 | 145 | 2005 |
| Small molecule inhibitors of influenza A and B viruses that act by disrupting subunit interactions of the viral polymerase G Muratore, L Goracci, B Mercorelli, Á Foeglein, P Digard, G Cruciani, ... Proceedings of the National Academy of Sciences 109 (16), 6247-6252, 2012 | 141 | 2012 |
| The cytomegalovirus DNA polymerase subunit UL44 forms a C clamp-shaped dimer BA Appleton, A Loregian, DJ Filman, DM Coen, JM Hogle Molecular cell 15 (2), 233-244, 2004 | 122 | 2004 |
| Human cytomegalovirus DNA replication: antiviral targets and drugs B Mercorelli, E Sinigalia, A Loregian, G Palù Reviews in medical virology 18 (3), 177-210, 2008 | 106 | 2008 |
| A broad anti-influenza hybrid small molecule that potently disrupts the interaction of polymerase acidic protein–basic protein 1 (PA-PB1) subunits S Massari, G Nannetti, J Desantis, G Muratore, S Sabatini, G Manfroni, ... Journal of Medicinal Chemistry 58 (9), 3830-3842, 2015 | 99 | 2015 |
| Protein–protein interactions as targets for antiviral chemotherapy A Loregian, HS Marsden, G Palu Reviews in medical virology 12 (4), 239-262, 2002 | 99 | 2002 |
| Selective anti-cytomegalovirus compounds discovered by screening for inhibitors of subunit interactions of the viral polymerase A Loregian, DM Coen Chemistry & biology 13 (2), 191-200, 2006 | 92 | 2006 |
| Residues of human cytomegalovirus DNA polymerase catalytic subunit UL54 that are necessary and sufficient for interaction with the accessory protein UL44 A Loregian, BA Appleton, JM Hogle, DM Coen Journal of virology 78 (1), 158-167, 2004 | 91 | 2004 |
| Separation methods for acyclovir and related antiviral compounds A Loregian, R Gatti, G Palu, EF De Palo Journal of Chromatography B: Biomedical Sciences and Applications 764 (1-2 …, 2001 | 83 | 2001 |
| Specific residues in the connector loop of the human cytomegalovirus DNA polymerase accessory protein UL44 are crucial for interaction with the UL54 catalytic subunit A Loregian, BA Appleton, JM Hogle, DM Coen Journal of virology 78 (17), 9084-9092, 2004 | 76 | 2004 |
| Optimization of small-molecule inhibitors of influenza virus polymerase: from thiophene-3-carboxamide to polyamido scaffolds S Lepri, G Nannetti, G Muratore, G Cruciani, R Ruzziconi, B Mercorelli, ... Journal of medicinal chemistry 57 (10), 4337-4350, 2014 | 74 | 2014 |
| Imperial College COVID-19 Response Team E Lavezzo, E Franchin, C Ciavarella, G Cuomo-Dannenburg, L Barzon, ... Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo …, 2020 | 73 | 2020 |
| Inhibition of human cytomegalovirus DNA polymerase by C-terminal peptides from the UL54 subunit A Loregian, R Rigatti, M Murphy, E Schievano, G Palu, HS Marsden Journal of virology 77 (15), 8336-8344, 2003 | 72 | 2003 |
| Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit: differences in structure and function relative … BA Appleton, J Brooks, A Loregian, DJ Filman, DM Coen, JM Hogle Journal of Biological Chemistry 281 (8), 5224-5232, 2006 | 71 | 2006 |
