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Luca Fornelli
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Progress in top-down proteomics and the analysis of proteoforms
TK Toby, L Fornelli, NL Kelleher
Annual review of analytical chemistry 9, 499-519, 2016
5882016
Best practices and benchmarks for intact protein analysis for top-down mass spectrometry
DP Donnelly, CM Rawlins, CJ DeHart, L Fornelli, LF Schachner, Z Lin, ...
Nature methods 16 (7), 587-594, 2019
3052019
Principles of electron capture and transfer dissociation mass spectrometry applied to peptide and protein structure analysis
KO Zhurov, L Fornelli, MD Wodrich, ÜA Laskay, YO Tsybin
Chemical Society Reviews 42 (12), 5014-5030, 2013
2262013
Middle-down analysis of monoclonal antibodies with electron transfer dissociation orbitrap fourier transform mass spectrometry
L Fornelli, D Ayoub, K Aizikov, A Beck, YO Tsybin
Analytical chemistry 86 (6), 3005-3012, 2014
2012014
Analysis of intact monoclonal antibody IgG1 by electron transfer dissociation Orbitrap FTMS
L Fornelli, E Damoc, PM Thomas, NL Kelleher, K Aizikov, E Denisov, ...
Molecular & Cellular Proteomics 11 (12), 1758-1767, 2012
1682012
Structural analysis of intact monoclonal antibodies by electron transfer dissociation mass spectrometry
YO Tsybin, L Fornelli, C Stoermer, M Luebeck, J Parra, S Nallet, FM Wurm, ...
Analytical chemistry 83 (23), 8919-8927, 2011
1552011
Top-down characterization of endogenous protein complexes with native proteomics
OS Skinner, NA Haverland, L Fornelli, RD Melani, LHF Do Vale, ...
Nature chemical biology 14 (1), 36-41, 2018
1422018
Accurate sequence analysis of a monoclonal antibody by top-down and middle-down orbitrap mass spectrometry applying multiple ion activation techniques
L Fornelli, K Srzentić, R Huguet, C Mullen, S Sharma, V Zabrouskov, ...
Analytical chemistry 90 (14), 8421-8429, 2018
1332018
Quantitation and identification of thousands of human proteoforms below 30 kDa
KR Durbin, L Fornelli, RT Fellers, PF Doubleday, M Narita, NL Kelleher
Journal of proteome research 15 (3), 976-982, 2016
1192016
Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk
I Ntai, L Fornelli, CJ DeHart, JE Hutton, PF Doubleday, RD LeDuc, ...
Proceedings of the National Academy of Sciences 115 (16), 4140-4145, 2018
982018
In-spray supercharging of peptides and proteins in electrospray ionization mass spectrometry
SM Miladinović, L Fornelli, Y Lu, KM Piech, HH Girault, YO Tsybin
Analytical chemistry 84 (11), 4647-4651, 2012
962012
Interlaboratory study for characterizing monoclonal antibodies by top-down and middle-down mass spectrometry
K Srzentic, L Fornelli, YO Tsybin, JA Loo, H Seckler, JN Agar, ...
Journal of the American Society for Mass Spectrometry 31 (9), 1783-1802, 2020
912020
Advancing top-down analysis of the human proteome using a benchtop quadrupole-orbitrap mass spectrometer
L Fornelli, KR Durbin, RT Fellers, BP Early, JB Greer, RD LeDuc, ...
Journal of proteome research 16 (2), 609-618, 2017
822017
A comprehensive pipeline for translational top-down proteomics from a single blood draw
TK Toby, L Fornelli, K Srzentić, CJ DeHart, J Levitsky, J Friedewald, ...
Nature protocols 14 (1), 119-152, 2019
812019
Mapping proteoforms and protein complexes from king cobra venom using both denaturing and native top-down proteomics
RD Melani, OS Skinner, L Fornelli, GB Domont, PD Compton, NL Kelleher
Molecular & Cellular Proteomics 15 (7), 2423-2434, 2016
802016
Top-down proteomics: Where we are, where we are going?
L Fornelli, TK Toby, LF Schachner, PF Doubleday, K Srzentić, CJ DeHart, ...
Journal of proteomics 175, 3, 2018
762018
An informatic framework for decoding protein complexes by top-down mass spectrometry
OS Skinner, PC Havugimana, NA Haverland, L Fornelli, BP Early, ...
Nature methods 13 (3), 237-240, 2016
762016
Observation of ion coalescence in Orbitrap Fourier transform mass spectrometry
MV Gorshkov, L Fornelli, YO Tsybin
Rapid Communications in Mass Spectrometry 26 (15), 1711-1717, 2012
752012
Unabridged analysis of human histone H3 by differential top-down mass spectrometry reveals hypermethylated proteoforms from MMSET/NSD2 overexpression
Y Zheng, L Fornelli, PD Compton, S Sharma, J Canterbury, C Mullen, ...
Molecular & Cellular Proteomics 15 (3), 776-790, 2016
712016
The Blood Proteoform Atlas: A reference map of proteoforms in human hematopoietic cells
RD Melani, VR Gerbasi, LC Anderson, JW Sikora, TK Toby, JE Hutton, ...
Science 375 (6579), 411-418, 2022
672022
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