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Olga Vasiljeva
Olga Vasiljeva
Vice President, CytomX Therapeutics Inc.
Подтвержден адрес электронной почты в домене cytomx.com
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Процитировано
Процитировано
Год
Cysteine cathepsins: from structure, function and regulation to new frontiers
V Turk, V Stoka, O Vasiljeva, M Renko, T Sun, B Turk, D Turk
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1824 (1), 68-88, 2012
14932012
Emerging roles of cysteine cathepsins in disease and their potential as drug targets
O Vasiljeva, T Reinheckel, C Peters, D Turk, V Turk, B Turk
Current pharmaceutical design 13 (4), 387-403, 2007
5622007
Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment
G Mikhaylov, U Mikac, AA Magaeva, VI Itin, EP Naiden, I Psakhye, ...
Nature nanotechnology 6 (9), 594-602, 2011
4292011
Tumor cell–derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer
O Vasiljeva, A Papazoglou, A Krüger, H Brodoefel, M Korovin, ...
Cancer research 66 (10), 5242-5250, 2006
4202006
Tumor-specific activation of an EGFR-targeting probody enhances therapeutic index
LR Desnoyers, O Vasiljeva, JH Richardson, A Yang, EEM Menendez, ...
Science translational medicine 5 (207), 207ra144-207ra144, 2013
2892013
Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity
J Rozman-Pungerčar, N Kopitar-Jerala, M Bogyo, D Turk, O Vasiljeva, ...
Cell Death & Differentiation 10 (8), 881-888, 2003
2422003
Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice
L Sevenich, U Schurigt, K Sachse, M Gajda, F Werner, S Müller, ...
Proceedings of the National Academy of Sciences 107 (6), 2497-2502, 2010
1832010
Dual contrasting roles of cysteine cathepsins in cancer progression: apoptosis versus tumour invasion
O Vasiljeva, B Turk
Biochimie 90 (2), 380-386, 2008
1482008
Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice
O Vasiljeva, M Korovin, M Gajda, H Brodoefel, L Bojic, A Krüger, ...
Oncogene 27 (30), 4191-4199, 2008
1262008
Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans
O Vasiljeva, M Dolinar, JR Pungerčar, V Turk, B Turk
FEBS letters 579 (5), 1285-1290, 2005
1212005
Autocatalytic processing of procathepsin B is triggered by proenzyme activity
JR Pungerčar, D Caglič, M Sajid, M Dolinar, O Vasiljeva, U Požgan, ...
The FEBS journal 276 (3), 660-668, 2009
1142009
A role for stefin B (cystatin B) in inflammation and endotoxemia
K Maher, BJ Kokelj, M Butinar, G Mikhaylov, M Manček-Keber, V Stoka, ...
Journal of biological chemistry 289 (46), 31736-31750, 2014
762014
Nitroxoline impairs tumor progression in vitro and in vivo by regulating cathepsin B activity
B Mirković, B Markelc, M Butinar, A Mitrović, I Sosič, S Gobec, O Vasiljeva, ...
Oncotarget 6 (22), 19027, 2015
702015
Cell type-specific functions of the lysosomal protease cathepsin L in the heart
D Spira, J Stypmann, DJ Tobin, I Petermann, C Mayer, S Hagemann, ...
Journal of biological chemistry 282 (51), 37045-37052, 2007
702007
Selective targeting of tumor and stromal cells by a nanocarrier system displaying lipidated cathepsin B inhibitor
G Mikhaylov, D Klimpel, N Schaschke, U Mikac, M Vizovisek, M Fonovic, ...
Angewandte Chemie 126 (38), 10241-10245, 2014
692014
Recombinant human cathepsin H lacking the mini chain is an endopeptidase
O Vasiljeva, M Dolinar, V Turk, B Turk
Biochemistry 42 (46), 13522-13528, 2003
592003
Non-invasive in vivo imaging of tumour-associated cathepsin B by a highly selective inhibitory DARPin
L Kramer, M Renko, J Završnik, D Turk, MA Seeger, O Vasiljeva, ...
Theranostics 7 (11), 2806, 2017
572017
Stefin B deficiency reduces tumor growth via sensitization of tumor cells to oxidative stress in a breast cancer model
M Butinar, MT Prebanda, J Rajković, B Jerič, V Stoka, C Peters, ...
Oncogene 33 (26), 3392-3400, 2014
572014
Anti-PDL1 antibodies, activatable anti-PDL1 antibodies, and methods of thereof
JW West, L Mei, SJ Moore, MTL Nguyen, DR Hostetter, O Vasiljeva, ...
US Patent 10,336,824, 2019
562019
Activatable antibodies that bind epidermal growth factor receptor and methods of use thereof
HB Lowman, LR Desnoyers, S Liu, JW West, JG Sagert, O Vasiljeva, ...
US Patent 9,120,853, 2015
512015
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Статьи 1–20